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Longitudinal microstructural changes in 18 amygdala nuclei resonate with cortical circuits and phenomics
The amygdala nuclei modulate distributed neural circuits that most likely evolved to respond to environmental threats and opportunities. So far, the...
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Dorsal and ventral fronto-amygdala networks underlie risky decision-making in age-related cognitive decline
Older adults often have difficulty in making decisions under uncertainty, increasing the risk of financial exploitation. However, it is still under...
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Disorganized functional architecture of amygdala subregional networks in obsessive-compulsive disorder
A precise understanding of amygdala-centered subtle networks may help refine neurocircuitry models of obsessive-compulsive disorder (OCD). We applied...
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Molecular and cellular evolution of the amygdala across species analyzed by single-nucleus transcriptome profiling
The amygdala, or an amygdala-like structure, is found in the brains of all vertebrates and plays a critical role in survival and reproduction....
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Evidence for postnatal neurogenesis in the human amygdala
The human amygdala is involved in processing of memory, decision-making, and emotional responses. Previous studies suggested that the amygdala may...
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Relationship between nuclei-specific amygdala connectivity and mental health dimensions in humans
There has been increasing interest in using neuroimaging measures to predict psychiatric disorders. However, predictions usually rely on large brain...
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Differential functional organization of amygdala-medial prefrontal cortex networks in macaque and human
Over the course of evolution, the amygdala (AMG) and medial frontal cortex (mPFC) network, involved in behavioral adaptation, underwent structural...
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Neuronal activity in the human amygdala and hippocampus enhances emotional memory encoding
Emotional events comprise our strongest and most valuable memories. Here we examined how the brain prioritizes emotional information for storage...
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Amygdala–pons connectivity is hyperactive and associated with symptom severity in depression
Knowledge of the neural underpinnings of processing sad information and how it differs in people with depression could elucidate the neural...
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EphB2 activation in neural stem cells in the basolateral amygdala facilitates neurogenesis and enhances long-term memory
Many brain diseases lead to a reduction in the number of functional neurons and it would be of value to be able to increase the number of neurons in...
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Global dissociation of the posterior amygdala from the rest of the brain during REM sleep
Rapid-eye-movement sleep (REMS) or paradoxical sleep is associated with intense neuronal activity, fluctuations in autonomic control, body paralysis...
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Treadmill exercise modulates the medial prefrontal-amygdala neural circuit to improve the resilience against chronic restraint stress
Aerobic exercise effectively ameliorates mental disorders including anxiety and depression. Current findings mainly attribute its neural mechanism to...
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Involvement of isoproterenol-induced intracellular Zn2+ dynamics in the basolateral amygdala in conditioned fear memory
Beta-adrenergic receptors in the basolateral amygdala play an essential role in fear memory, while the physiological role of intracellular Zn 2+ ...
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GABAergic circuits of the basolateral amygdala and generation of anxiety after traumatic brain injury
Traumatic brain injury (TBI) has reached epidemic proportions around the world and is a major public health concern in the United States....
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Basolateral and central amygdala orchestrate how we learn whom to trust
Cooperation and mutual trust are essential in our society, yet not everybody is trustworthy. In this fMRI study, 62 healthy volunteers performed a...
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Lateralization of the 5-HT1A receptors in the basolateral amygdala in metabolic and anxiety responses to chronic restraint stress
Behavioral and functional studies describe hemispheric asymmetry in anxiety and metabolic behaviors in responses to stress. However, no study has...
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Stress deficits in reward behaviour are associated with and replicated by dysregulated amygdala-nucleus accumbens pathway function in mice
Reduced reward interest/learning and reward-to-effort valuation are distinct, common symptoms in neuropsychiatric disorders for which chronic stress...
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Encoding of facial features by single neurons in the human amygdala and hippocampus
Faces are salient social stimuli that attract a stereotypical pattern of eye movement. The human amygdala and hippocampus are involved in various...
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Moderate white light exposure enhanced spatial memory retrieval by activating a central amygdala-involved circuit in mice
Light exposure can profoundly affect neurological functions and behaviors. Here, we show that short-term exposure to moderate (400 lux) white light...
