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Impacts of Acrylamide on testis and spermatozoa
Acrylamide (ACR) is an industrial chemical used to produce polyacrylamide, a synthetic polymer with a wide range of applications. Depending on the...
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ALKBH5 in mouse testicular Sertoli cells regulates Cdh2 mRNA translation to maintain blood–testis barrier integrity
BackgroundRNA N 6 -methyladenosine (m 6 A) is involved in mammalian spermatogenesis. In both germ cells and Leydig cells, ALKBH5 regulates...
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Zinc Improves Semen Parameters in High-Fat Diet-Induced Male Rats by Regulating the Expression of LncRNA in Testis Tissue
This study aimed to identify differentially expressed LncRNAs in testis tissue of male rats induced by high-fat diet and their changes after zinc...
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Testis transcriptome profiling identified lncRNAs involved in spermatogenic arrest of cattleyak
Cattleyaks are the crossbred offspring between cattle and yaks, exhibiting the prominent adaptability to the harsh environment as yaks and much...
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Effect of a bradykinin potentiating factor separated from honey bee venom on thyroid gland and testis in hypothyroid white rats
BackgroundAnimal venoms have been known as a source of drugs beneficial to human health. Accordingly, this study was designed to determine the effect...
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PA1 participates in the maintenance of blood–testis barrier integrity via cooperation with JUN in the Sertoli cells of mice
BackgroundThe blood–testis barrier (BTB) is essential to the microenvironment of spermatogenesis, and Sertoli cells provide the cellular basis for...
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Dissecting Collective Cell Behavior in Migrating Testis Myotubes in Drosophila
Collective cell migration has a key role in tissue morphogenesis, wound healing, tissue regeneration, and cancer invasion. In recent years, different...
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“Effect of Sunset Yellow on Testis: Molecular Evaluation, and Protective Role of Coenzyme Q10 in Male Sprague-Dawley Rats”
In recent years, Sunset Yellow (SY) has been widely used as a food additive, sparking debates about its potential toxicity. This research aims to...
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Chronic exposure to aquacultural stressors affects pituitary-testis axis in the Mozambique tilapia Oreochromis mossambicus
Reproduction in fish is modulated by several factors that include environmental and endocrine components. The aim of this study was to elucidate the...
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Y chromosomal noncoding RNAs regulate autosomal gene expression via piRNAs in mouse testis
BackgroundDeciphering the functions of Y chromosome in mammals has been slow owing to the presence of repeats. Some of these repeats transcribe...
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Immature rat testis sustained long-term development using an integrative model
BackgroundXenotransplantation has been primarily performed using fresh donor tissue to study testicular development for about 20 years, and whether...
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The opioid peptide β-endorphin interferes with the pituitary-testis axis in the Mozambique tilapia Oreochromis mossambicus
Although the involvement of β-endorphin (β-ERP) in vertebrate reproduction has been suggested, its role in testicular activity is not clear in fish....
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Seasonal modulation of the testis transcriptome reveals insights into hibernation and reproductive adaptation in Onychostoma macrolepis
The Onychostoma macrolepis have a unique survival strategy, overwintering in caves and returning to the river for reproduction in summer. The current...
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Gpx4, Selenov, and Txnrd3 Are Three Most Testis-Abundant Selenogenes Resistant to Dietary Selenium Concentrations and Actively Expressed During Reproductive Ages in Rats
Almost all selenogenes are expressed in the testis, and those have the highest and constant expressions will be the primary candidates for functional...
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Kindlin-2 in Sertoli cells is essential for testis development and male fertility in mice
Kindlin-2 is known to play important roles in the development of mesoderm-derived tissues including myocardium, smooth muscle, cartilage and blood...
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LncRNA Tug1 maintains blood–testis barrier integrity by modulating Ccl2 expression in high-fat diet mice
Sertoli cells are essential for spermatogenesis in the testicular seminiferous tubules by forming blood–testis barrier (BTB) and creating a unique...
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Effect of Titanium Dioxide and Silver Nanoparticles on Mitochondrial Dynamics in Mouse Testis Tissue
This study was performed to investigate whether the toxicity of nanoparticles (Ag NPs or TiO 2 NPs) affected mitochondrial dynamics (mitochondrial...
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Polyubiquitin gene Ubb is required for upregulation of Piwi protein level during mouse testis development
Testis development, including early embryonic gonad formation and late postnatal spermatogenesis, is essential for the reproduction of higher...
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Improved conditions of a whole testis organ culture system in terms of spermatogonial proliferation levels in marine medaka (Oryzias dancena)
In vitro spermatogenesis can be performed for marine medaka ( Oryzias dancena ) via whole testis organ cultures, but spermatogenesis could only be...
