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Transcriptomic contributions to a modern cytoarchitectonic parcellation of the human cerebral cortex
Transcriptomic contributions to the anatomical, functional, and network layout of the human cerebral cortex (HCC) have become a major interest in...
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Divergent Cellular Energetics, Glutamate Metabolism, and Mitochondrial Function Between Human and Mouse Cerebral Cortex
Disruptions of brain energy and neurotransmitter metabolism are associated with several pathological conditions including neurodegenerative diseases...
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Doublecortin-Expressing Neurons in Human Cerebral Cortex Layer II and Amygdala from Infancy to 100 Years Old
A cohort of morphologically heterogenous doublecortin immunoreactive (DCX +) “immature neurons” has been identified in the cerebral cortex largely...
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How mechanisms of stem cell polarity shape the human cerebral cortex
Apical–basal progenitor cell polarity establishes key features of the radial and laminar architecture of the developing human cortex. The unique...
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Development and Developmental Disorders of the Cerebral Cortex
The cerebral cortex can be divided into a large isocortex, a much smaller allocortex (the hippocampal formation and the olfactory cortex), and a...
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Neuropeptide FF (NPFF)-positive nerve cells of the human cerebral cortex and white matter in controls, selected neurodegenerative diseases, and schizophrenia
We quantified and determined for the first time the distribution pattern of the neuropeptide NPFF in the human cerebral cortex and subjacent white...
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Features of the Development of the Human Cerebral Cortex during the Second Trimester of Gestation
The aim of the present work was to study patterns of the postmigration development of neurons accompanying stratification of the dorsal precentral...
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Cerebral organoids transplantation repairs infarcted cortex and restores impaired function after stroke
Stroke usually causes prolonged or lifelong disability, owing to the permanent loss of infarcted tissue. Although a variety of stem cell...
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Blood vessel remodeling in the cerebral cortex induced by binge alcohol intake in mice
Ethanol is toxic to the brain and causes various neurological disorders. Although ethanol can directly exert toxicity on neurons, it also acts on...
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Comparing mouse and human cingulate cortex organization using functional connectivity
The subdivisions of the extended cingulate cortex of the human brain are implicated in a number of high-level behaviors and affected by a range of...
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Neuroprotective Potential of Tannic Acid Against Neurotoxic Outputs of Monosodium Glutamate in Rat Cerebral Cortex
Glutamate in monosodium glutamate (MSG), which is widely used in the food industry, has an important role in major brain functions such as memory,...
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Overview: Research on the Genetic Architecture of the Developing Cerebral Cortex in Norms and Diseases
The human brain is characterized by high cell numbers, diverse cell types with diverse functions, and intricate connectivity with an exceedingly...
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Neurogenesis of Cerebral Cortex Projection Neurons
The cerebral cortex develops from the dorsal telencephalon (or pallium) at the rostral end of the embryonic neural tube. Neurons in the cerebral...
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Neurogenesis of Cerebral Cortex Projection Neurons
The cerebral cortex develops from the dorsal telencephalon (or pallium) at the rostral end of the embryonic neural tube. Neurons in the cerebral...
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Utilizing human cerebral organoids to model breast cancer brain metastasis in culture
BackgroundMetastasis, the spread, and growth of malignant cells at secondary sites within a patient’s body, accounts for over 90% of cancer-related...
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Organization of the Cortex
The cerebral cortex, also known as the isocortex or neocortex, consists of two hemispheres, each divided into five lobes that correlate with the main...
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Entorhinal cortex astrocytic atrophy in human frontotemporal dementia
The pathophysiology of Fronto Temporal Dementia (FTD) remains poorly understood, specifically the role of astroglia. Our aim was to explore the...
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Defining putative tertiary sulci in lateral prefrontal cortex in chimpanzees using human predictions
Similarities and differences in brain structure and function across species are of major interest in systems neuroscience, comparative biology, and...
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Untargeted Metabolomic Analysis Reveals the Metabolic Disturbances and Exacerbation of Oxidative Stress in the Cerebral Cortex of a BTBR Mouse Model of Autism
The etiology and pathology of autism spectrum disorders (ASDs) are still poorly understood, which largely limit the treatment and diagnosis of ASDs....
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Tbr1 Misexpression Alters Neuronal Development in the Cerebral Cortex
Changes in the transcription factor (TF) expression are critical for brain development, and they may also underlie neurodevelopmental disorders....
