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Liver Carcinogenesis Methods and Protocols
This volume discusses the latest advancements in modern methodologies used to study liver carcinogenesis. The first half of this book describes...
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The Parasitism and Tumors Carcinogenesis: A Review Subject
BackgroundMulti-factorial reasons are an induction to cause cancer. Different infections and infestations with viruses, bacteria, and parasites have...
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Environmental impact on carcinogenesis under BRCA1 haploinsufficiency
Cancer is the primary cause of human mortality in Japan since 1981. Although numerous novel therapies have been developed and applied in clinics, the...
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Molecular Mechanisms of Metal-Induced Carcinogenesis
Occupational and environmental exposures to metals are strongly associated with an increased risk of various cancers. Although carcinogenesis caused...
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Emerging paradigms: unmasking the role of oxidative stress in HPV-induced carcinogenesis
The contribution of the human papillomavirus (HPV) to cancer is significant but not exclusive, as carcinogenesis involves complex mechanisms, notably...
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Diffuse subtype-specific gastric carcinogenesis associated with dysregulation of Notch signaling pathways
Gastric tumors are the third leading cause of cancer-related mortality worldwide. This study investigates the effects of Notch signaling pathway...
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Unveiling the gastric microbiota: implications for gastric carcinogenesis, immune responses, and clinical prospects
High-throughput sequencing has ushered in a paradigm shift in gastric microbiota, breaking the stereotype that the stomach is hostile to...
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Lysine-63-linked polyubiquitination: a principal target of cadmium carcinogenesis
Cadmium is an environmental pollutant that constitutes a major danger to human health. It is considered a definite human carcinogen. The lung and...
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Microbial metabolite trimethylamine-N-oxide induces intestinal carcinogenesis through inhibiting farnesoid X receptor signaling
PurposeMicrobial dysbiosis is considered as a hallmark of colorectal cancer (CRC). Trimethylamine-N-oxide (TMAO) as a gut microbiota-dependent...
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Spatiotemporal analysis of tumour-infiltrating immune cells in biliary carcinogenesis
BackgroundIntraductal papillary neoplasms (IPN) and biliary epithelial neoplasia (BilIN) are well‐defined precursor lesions of biliary tract...
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Effect of Polyphenolic Composition BP-C2 on Lung Carcinogenesis Induced by Urethane in Progeny of Irradiated Male BALB/c Mice
We studied the effects of polyphenolic composition BP-C2, comprising molybdenum with lignin derivatives, on lung carcinogenesis induced by urethane...
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The relationship between pepsinogen C and gastric carcinogenesis: a transgene and population study
BackgroundPepsinogen C (PGC) is expressed in chief cells, fundic mucous neck cells, and pyloric gland cells of gastric epithelium and also in breast,...
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Age distribution and a multi-stage theory of carcinogenesis: 70 years on
The Armitage Doll model demonstrates that the impact of age-dependent exposure to carcinogenic factors depends on whether the induced change occurs...
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Bioinformatics analysis of immune characteristics in tumors with alternative carcinogenesis pathways induced by human papillomaviruses
BackgroundHuman papillomaviruses (HPVs) induce a subset of head and neck squamous cell carcinomas (HNSCC) and anogenital cancers, particularly...
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Inducible TgfbR1 and Pten deletion in a model of tongue carcinogenesis and chemoprevention
Head and neck squamous cell carcinoma (HNSCC) is a significant public health problem, with a need for novel approaches to chemoprevention and...
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Correlations of Expression Levels of Lung Cancer Marker Gene Eno2 and Genes of Carcinogenesis and Apoptosis in the Hypothalamus of Mice with Depression-Like Behavior
We experimentally demonstrated that chronic social stress during the development of a depression-like state enhances lung metastasis and modifies the...
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Role of Wisteria floribunda agglutinin binding glycans in carcinogenesis and metastasis of cholangiocarcinoma
Aberrant glycosylation is an important factor in facilitating tumor progression and therapeutic resistance. In this study, using Wisteria floribunda ...
