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Evolution of Pathogenicity and Virulence
Evolutionary biologists define virulence as reduction in host fitness (survival and reproduction) caused by pathogens. The avirulence hypothesis...
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The Coincidental Evolution of Virulence Partially Explains the Virulence in a Generalist Entomopathogenic
PurposeThe parasites’ virulence is labile after jumping to a new host species, and it might derivate in gaining virulence against a new host as a...
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A candidate virulence factor of Eimeria tenella (EtROP30) predicted by virulence enhancement of transgenic Toxoplasma gondii
Difficulties of in vitro culture and genetic manipulation of Eimeria tenella have hindered the screening of virulence factors in this parasite. In...
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Klebsiella pneumoniae Virulence Factors and Biofilm Components: Synthesis, Structure, Function, and Inhibitors
Klebsiella pneumoniae is a Gram-negative pathogen capable of causing a diverse array of infections in humans. It belongs to the group of ESKAPE...
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Pseudomonas aeruginosa Virulence Factors and Biofilm Components: Synthesis, Structure, Function and Inhibitors
Pseudomonas aeruginosa is a versatile opportunistic bacterium reasons for hospital-acquired infections specifically to the patients suffering from...
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Acinetobacter baumannii Virulence Factors and Biofilm Components: Synthesis, Structure, Function, and Inhibitors
Acinetobacter baumannii (A. baumannii) is a Gram-negative opportunistic human pathogen, and the drastic dissemination of multidrug resistance in A....
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Enterococcus faecium Virulence Factors and Biofilm Components: Synthesis, Structure, Function, and Inhibitors
Enterococcus faecium, a Gram-positive bacterium belonging to the family Enterococcaceae is known for its clinical significance due to its ability to...
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Biochemical, Molecular, and Computational Techniques for the Determination of Virulence Factors of ESKAPE Pathogens
Emerging antibiotic resistance and its spreading dynamics have reached an alarming level, a global challenge. Overuse and Misuse of effective...
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Anti-virulence to Counter the AMR Conundrum: Principles and Strategies
Antibiotic resistance for a large diversity of clinically significant pathogens has been observed with increasing frequency over the past several...
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Anti-virulence to Counter the AMR Conundrum: Principles and Strategies
Antibiotic resistance for a large diversity of clinically significant pathogens has been observed with increasing frequency over the past several...
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Mobilizable plasmids drive the spread of antimicrobial resistance genes and virulence genes in Klebsiella pneumoniae
BackgroundKlebsiella pneumoniae is a notorious clinical pathogen and frequently carries various plasmids, which are the main carriers of...
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Virulence evaluation of Israeli Marek’s disease virus isolates from commercial poultry using their meq gene sequence
Fifty-seven Gallid alphaherpesvirus 2 (GaHV-2) isolates, collected during a 30-year period (1990–2019) from commercial poultry flocks affected by...
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Nucleotide at position 66 of NS2A in Japanese encephalitis virus is associated with the virulence and proliferation of virus
Most wild strains of Japanese encephalitis virus (JEV) produce NS1’ protein, which plays an important role in viral infection and immune escape. The...
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Rapid emergence and transmission of virulence-associated mutations in the oral poliovirus vaccine following vaccination campaigns
There is an increasing burden of circulating vaccine-derived polioviruses (cVDPVs) due to the continued use of oral poliovirus vaccine (OPV)....
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Staphylococcus aureus Virulence Factors and Biofilm Components: Synthesis, Structure, Function and Inhibitors
Staphylococcus aureus is classified as an ESKAPE pathogen, possessing both multi-drug resistance and virulence factors. S. aureus exhibits...
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Enterobacter spp. Virulence Factors and Biofilm Components: Synthesis, Structure, Function, and Inhibitors
Enterobacter species are multidrug-resistant opportunistic pathogens that produce a variety of virulence factors (VF) to cause disease. They are...
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Assessment of African swine fever vaccine candidate ASFV-G-∆MGF in a reversion to virulence study
African swine fever (ASF) has gained panzootic dimensions and commercial vaccines are still unavailable. Recently, a series of live attenuated...
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Bacterial Adhesion, Virulence, and Biofilm Formation
The adhesion of bacteria to implanted biomaterial and human tissue surfaces is the first and essential step in the pathogenesis of infection....
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Helicobacter pylori Virulence Factors, Pathogenicity, and Gastric Cancer
Gastric cancer is a common cancer with a high incidence and mortality rate worldwide. Unfortunately, early-stage gastric cancer is asymptomatic....
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Adhesion and virulence properties of native Metarhizium fungal strains from Burkina Faso for the control of malaria vectors
BackgroundLocal strains of the entomopathogenic fungus Metarhizium pingshaense in Burkina Faso have demonstrated remarkable virulence against...
