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Reactivation of varicella zoster virus following trigeminal schwannoma resection
Varicella zoster is found exclusively in humans. Infected people with this virus result in chickenpox followed by dormant virus within neural...
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The ultrastructure of macaque mesencephalic trigeminal nucleus neurons
Primary afferents originating from the mesencephalic trigeminal nucleus provide the main source of proprioceptive information guiding mastication,...
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Optogenetic Approach in Trigeminal Neuralgia and Potential Concerns: Preclinical Insights
The integration of optogenetics in the trigeminal pain circuitry broadens and reinforces existing pain investigations. Similar to research on spinal...
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TET1 Participates in Complete Freund’s Adjuvant-induced Trigeminal Inflammatory Pain by Regulating Kv7.2 in a Mouse Model
Trigeminal inflammatory pain is one of the most severe pain-related disorders in humans; however, the underlying mechanisms remain largely unknown....
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Electrophysiological characterization of a CaV3.1 calcium channel mutation linked to trigeminal neuralgia
Trigeminal neuralgia is a rare and debilitating disorder that affects one or more branches of the trigeminal nerve, leading to severe pain attacks...
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Expression of CGRP in the Trigeminal Ganglion and Its Effect on the Polarization of Macrophages in Rats with Temporomandibular Arthritis
Calcitonin gene-related peptide (CGRP) is synthesized and secreted by trigeminal ganglion neurons, and is a key neuropeptide involved in pain and...
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Migraine Type-Dependent Patterns of Brain Activation After Facial and Intranasal Trigeminal Stimulation
In migraine, the trigeminal nerve is intimately involved in the pathophysiology of the disease. We hypothesized that alterations in the sensory...
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Trigeminal nerve stimulation: a current state-of-the-art review
Nearly 5 decades ago, the effect of trigeminal nerve stimulation (TNS) on cerebral blood flow was observed for the first time. This implication...
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Sympathetic control of the coronary circulation during trigeminal nerve stimulation in humans
PurposeWe sought to investigate the sympathetic mechanism controlling coronary circulation during trigeminal nerve stimulation in healthy women.
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Whole Blood Transcriptome Analysis in Patients with Trigeminal Neuralgia: a Prospective Clinical Study
Trigeminal neuralgia (TN) brings a huge burden to patients, without long-term effective treatment. This study aimed to explore the differentially...
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Optogenetic Inhibition of Glutamatergic Neurons in the Dysgranular Posterior Insular Cortex Modulates Trigeminal Neuropathic Pain in CCI-ION Rat
In individuals with chronic neuropathic pain, the posterior insular cortex (PIC) has been found to exhibit increased glutamatergic activity, and the...
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Percutaneous balloon compression for trigeminal neuralgia: experience and surgical techniques from a single institution
ObjectiveThe treatment experience and the technical skill with percutaneous balloon compression (PBC) for treatment of primary trigeminal neuralgia...
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Longitudinal alterations of the cisternal segment of trigeminal nerve and brain pain-matrix regions in patients with trigeminal neuralgia before and after treatment
BackgroundTrigeminal neuralgia (TN) is the most common type of chronic neuropathic facial pain, but the etiology and pathophysiological mechanisms...
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Foxg1 Modulation of the Prkcd Gene in the Lateral Habenula Mediates Trigeminal Neuralgia-Associated Anxiety-Like Behaviors in Mice
Trigeminal Neuralgia (TN) is a debilitating disorder frequently accompanied by mood complications such as depression and anxiety. The current study...
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Electrophysiological and computational analysis of Cav3.2 channel variants associated with familial trigeminal neuralgia
Trigeminal neuralgia (TN) is a rare form of chronic neuropathic pain characterized by spontaneous or elicited paroxysms of electric shock-like or...
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Early Cerebellar Development in Relation to the Trigeminal System
Despite the wealth of knowledge of adult cerebellar connectivity, little is known about the developmental mechanisms that underpin its development....
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ALPK1 Expressed in IB4-Positive Neurons of Mice Trigeminal Ganglions Promotes MIA-Induced TMJ pain
Pain is one of the main reasons for patients with temporomandibular joint (TMJ) disorders seeking medical care. However, there is no effective...
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