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A combined spatial score of granzyme B and CD68 surpasses CD8 as an independent prognostic factor in TNM stage II colorectal cancer
BackgroundPrevious assessments of peritumoral inflammatory infiltrate in colorectal cancer (CRC) have focused on the role of CD8 + T lymphocytes. We...
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Registry-derived stage (RD-Stage) for capturing cancer stage at diagnosis for endometrial cancer
BackgroundCapture of cancer stage at diagnosis is important yet poorly reported by health services to population-based cancer registries. In this...
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The Glasgow Microenvironment Score and risk and site of recurrence in TNM I–III colorectal cancer
BackgroundGlasgow Microenvironment Score (GMS) stratifies long-term survival into three groups based on tumour phenotype: peritumoural inflammation...
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Lymphocyte to C-reactive protein ratio could better predict the prognosis of patients with stage IV cancer
BackgroundSystemic inflammation is currently regarded as a hallmark of cancer. This study aimed to accurately clarify the prognostic value of various...
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Development and validation of prognostic nomograms based on De Ritis ratio and clinicopathological features for patients with stage II/III colorectal cancer
BackgroundMetabolic derangements and systemic inflammation are related to the progression of colorectal cancer (CRC) and the prognoses of these...
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Nomogram to predict overall survival of patients receiving radical gastrectomy and incomplete peri-operative adjuvant chemotherapy for stage II/III gastric cancer: a retrospective bi-center cohort study
BackgroundTo establish a nomogram to predict the probability of survival of patients with stage II/III gastric cancer (GC) who received incomplete...
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A population-based validation study of the 8th edition UICC/AJCC TNM staging system for cutaneous melanoma
BackgroundThe 8 th edition UICC/AJCC TNM8 (Tumour, Nodes, Metastasis) melanoma staging system introduced several modifications from the 7 th edition...
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Association of the SHOX2 and RASSF1A methylation levels with the pathological evolution of early-stage lung adenocarcinoma
Background The methylation of SHOX2 and RASSF1A shows promise as a potential biomarker for the early screening of lung cancer, offering a solution to...
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Integrated nomogram based on five stage-related genes and TNM stage to predict 1-year recurrence in hepatocellular carcinoma
BackgroundThe primary tumor, regional lymph nodes and distant metastasis (TNM) stage is an independent risk factor for 1-year hepatocellular...
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Protein prognostic biomarkers in stage II colorectal cancer: implications for post-operative management
Colorectal cancer (CRC) poses a significant threat to many human lives worldwide and survival following resection is predominantly stage dependent....
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Tertiary lymphoid structure score: a promising approach to refine the TNM staging in resected non-small cell lung cancer
BackgroundWe previously proposed an immune cell score (tumour node metastasis (TNM)-Immune cell score) classifier as an add-on to the existing TNM...
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Development and validation of a prognostic nomogram for early stage non-small cell lung cancer: a study based on the SEER database and a Chinese cohort
ObjectiveThis study aimed to construct a nomogram to effectively predict the overall survival (OS) of patients with early-stage non-small-cell lung...
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Tumor infiltrating lymphocyte stratification of prognostic staging of early-stage triple negative breast cancer
The importance of integrating biomarkers into the TNM staging has been emphasized in the 8 th Edition of the American Joint Committee on Cancer (AJCC)...
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Effects of deficient mismatch repair on the prognosis of patients with stage II and stage III colon cancer during different postoperative periods
BackgroundWe evaluated the prognostic role of deficient mismatch repair (dMMR) systems in stage II and stage III colon cancer patients during...
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Higher body mass index was associated with better prognosis in diabetic patients with stage II colorectal cancer
PurposeThe purpose of this study is to analyze the effect of body mass index (BMI) on patients with concurrent colorectal cancer (CRC) and type 2...
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Impact of preoperative white blood cell count on outcomes in different stage colorectal cancer patients undergoing surgical resection: a single-institution retrospective cohort study
PurposeTo explore the association between preoperative WBC count and the long-term survival outcomes and clinical outcomes in different stage...
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Development and validation of a Radiopathomics model based on CT scans and whole slide images for discriminating between Stage I-II and Stage III gastric cancer
ObjectiveThis study aimed to develop and validate an artificial intelligence radiopathological model using preoperative CT scans and postoperative...
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Establishment and validation of a novel nomogram incorporating clinicopathological parameters into the TNM staging system to predict prognosis for stage II colorectal cancer
BackgroundSurvival outcomes are significantly different in stage II colorectal cancer (CRC) patients with diverse clinicopathological features. The...
