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  1. Sex Differences in Pharmacokinetics

    Because women have been excluded from most clinical trials, assessment of sex differences in pharmacokinetics is available for a minority of...
    Irving Zucker, Brian J. Prendergast in Sex and Gender Effects in Pharmacology
    Chapter 2023
  2. Sex Differences in Vascular Function

    Sex is an important biological variable that impacts several organism functions at the genetic, molecular, and cellular levels. Sex differences are...
    Tiago J. Costa, Rita C. Tostes in Cardiovascular Neuroendocrinology
    Chapter 2023
  3. Sex Differences in Brain Function and Dysfunction

    Does sex matter when it comes to brain function? This volume attempts to answer this very important question which is of relevance to the disciplines...

    Claire Gibson, Liisa A. M. Galea in Current Topics in Behavioral Neurosciences
    Book 2023
  4. Sex Differences in Social Cognition

    Several studies have demonstrated sex differences in empathy and social abilities. This chapter reviews studies on sex differences in the brain,...
    Chapter Open access 2023
  5. Sex Differences in HIV Infection

    Biological sex has wide-ranging impacts on HIV infection spanning differences in acquisition risk, the pathogenesis of untreated infection, impact of...
    Chapter 2023
  6. Sex Differences in Glucose Homeostasis

    Sexual dimorphism has been demonstrated to have an effect on various physiological functions. In this regard, researchers have investigated its...
    Ebru Arioglu-Inan, Gizem Kayki-Mutlu in Sex and Gender Effects in Pharmacology
    Chapter 2023
  7. Sex Differences in Neuroendocrine-Immune Interactions

    The contribution of sex to differences in immune function is integral for our understanding of diseases and disorders; however, systematic study of...
    MiJin Cho, Gladys Shaw, ... Gretchen N. Neigh in Neuroendocrine-Immune System Interactions
    Chapter 2023
  8. Genetics of Sex Differences in Immunity

    Women have a stronger immune response and a higher frequency of most autoimmune diseases than men. While much of the difference between men and women...
    Chapter 2023
  9. Sex-Gender-Based Differences in Metabolic Diseases

    Sexual dimorphism creates different biological and cellular activities and selective regulation mechanisms in males and females, thus generating...
    Ilaria Campesi, Margherita Ruoppolo, ... Michele Costanzo in Sex and Gender Effects in Pharmacology
    Chapter 2023
  10. Sex-Linked Differences in Malaria Risk Across the Lifespan

    Despite the high burden of malaria worldwide, there is surprisingly scarce research on sex-based differences in malaria outside of pregnancy. A more...
    Jessica Briggs, Margaret Murray, ... Prasanna Jagannathan in Sex and Gender Differences in Infection and Treatments for Infectious Diseases
    Chapter 2023
  11. Sex Differences in Dementia

    Background Women in many cohorts have a higher risk for Alzheimer’s disease (AD), the most common form of dementia....
    Eef Hogervorst, Sophie Temple, Emma O’Donnell in Sex Differences in Brain Function and Dysfunction
    Chapter 2022
  12. Sex Differences in Pain and Its Treatment

    Pain is a highly personal experience. Pain is often considered to be a purely neurologic phenomenon, but in actuality, it is a combination of both...
    Chapter 2023
  13. Sex differences and sex-specific regulation of motivated behavior by Melanin-concentrating hormone: a short review

    Recent preclinical research exploring how neuropeptide transmitter systems regulate motivated behavior reveal the increasing importance of sex as a...

    Isabel R. K. Kuebler, Mauricio Suárez, Ken T. Wakabayashi in Biology of Sex Differences
    Article Open access 03 April 2024
  14. Sex Differences in Social Cognition

    In this review we explore the sex differences underlying various types of social cognition. Particular focus will be placed on the behaviors of...
    Pietro Paletta, Noah Bass, ... Elena Choleris in Sex Differences in Brain Function and Dysfunction
    Chapter 2022
  15. Sex Differences in the Evaluation and Treatment of Stroke

    There are differences in the prevalence and strength of risk factors in women, along with sex-specific risk factors such as pregnancy. Women have a...
    Sonia K. Singh, Louise McCullough in Sex and Gender Effects in Pharmacology
    Chapter 2023
  16. Sex Differences in Pain with Emphasis on Neuroimmune Interactions

    To date, the mechanisms underlying how neuroimmune interactions contribute to sex dimorphism of chronic pain remain elusive. Although women suffer...
    Xin Luo, Jasmine Ji, Ru-Rong Ji in Neuroimmune Interactions in Pain
    Chapter 2023
  17. Sex differences in brain protein expression and disease

    Most complex human traits differ by sex, but we have limited insight into the underlying mechanisms. Here, we investigated the influence of...

    Aliza P. Wingo, Yue Liu, ... Thomas S. Wingo in Nature Medicine
    Article Open access 31 August 2023
  18. Sex Differences in Cognition Across Aging

    Sex and gender differences are seen in cognitive disturbances in a variety of neurological and psychiatry diseases. Men are more likely to have...
    Bonnie H. Lee, Jennifer E. Richard, ... Liisa A. M. Galea in Sex Differences in Brain Function and Dysfunction
    Chapter 2022
  19. Sex and gender differences in drug treatment: experiences from the knowledge database Janusmed Sex and Gender

    Background

    Evidence from clinical research indicates that men and women can differ in response to drug treatment. The knowledge database Janusmed Sex...

    Linnéa Karlsson Lind, Diana M. Rydberg, Karin Schenck-Gustafsson in Biology of Sex Differences
    Article Open access 12 May 2023
  20. Biological and Clinical Implications of Sex-Specific Differences in Alzheimer’s Disease

    Mounting evidence indicates that the female sex is a risk factor for Alzheimer’s disease (AD), the most common cause of dementia worldwide. Decades...
    Jose A. Santiago, Judith A. Potashkin in Sex and Gender Effects in Pharmacology
    Chapter 2023
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