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Serotonin syndrome: A pharmacovigilance comparative study of drugs affecting serotonin levels
BackgroundSerotonin syndrome is a rare and potentially fatal adverse drug reaction caused by serotonergic drugs and is due to an increase in...
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Serotonin in the Cerebellum
SerotoninSerotonin (5-hydroxytryptamine, 5-HT) is widely present in the brain, including in the cerebellar cortexCerebellar cortex and cerebellar...
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Serotonin regulation of behavior via large-scale neuromodulation of serotonin receptor networks
Although we understand how serotonin receptors function at the single-cell level, what role different serotonin receptors play in regulating...
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No association between peripheral serotonin-gene-related DNA methylation and brain serotonin neurotransmission in the healthy and depressed state
BackgroundMethylation of serotonin-related genes has been proposed as a plausible gene-by-environment link which may mediate environmental stress,...
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Systematic review of studies using platelet serotonin content to assess bioeffect of serotonin reuptake inhibitors at the serotonin transporter
RationaleAssessment of the bioeffect of serotonin reuptake inhibitors (SRIs, including both selective serotonin reuptake inhibitors (SSRIs) and...
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Serotonin as a biomarker of toxin-induced Parkinsonism
BackgroundLoss of dopaminergic neurons underlies the motor symptoms of Parkinson’s disease (PD). However stereotypical PD symptoms only manifest...
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Linezolid-associated serotonin toxicity: a systematic review
PurposeThis systematic review aims to evaluate the existing evidence associating linezolid to serotonin toxicity when used as monotherapy or when...
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Zacopride stimulates 5-HT4 serotonin receptors in the human atrium
Zacopride (4-amino-5-chloro-2-methoxy-N-(quinuclidin-3-yl)-benzamide) is a potent agonist in human 5-HT 4 serotonin receptors in vitro and in the...
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Focal pharmacological manipulation of serotonin signaling in the amygdala does not alter social behavior
Serotonin signaling plays critical roles in social and emotional behaviors. Likewise, decades of research demonstrate that the amygdala is a prime...
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Mosapride stimulates human 5-HT4-serotonin receptors in the heart
Mosapride (4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl) methyl]-2-morpholinyl]-methyl] benzamide) is a potent agonist at gastrointestinal 5-HT 4 ...
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Effect of gut microbiome on serotonin metabolism: a personalized treatment approach
Several factors including diet, exercise, and medications influence the makeup of the resilient but adaptable gut microbiome. Bacteria in the gut...
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Recent Advances in Nanomaterials Based Optical Sensors for the Detection of Melatonin and Serotonin
In this review paper we discussed the detection of melatonin and serotonin by using various optical methods. Melatonin and serotonin are very...
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Association of Serotonin Receptor Gene Polymorphisms with Regulatory and Adaptive Capacities of Medical Students
Molecular genetic analysis of polymorphic variants of serotonin receptor genes ( HTR2C and HTR2A ) was performed in 89 healthy medical students and...
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Increased histone acetylation levels or a serotonin precursor reinstate the context memory impaired by the serotonin receptor blocker methiothepin
Previously, it was demonstrated that the presumed increase of serotonin (5-HT) release due to the presence of 5-hydroxytryptophan (5-HTP) and changes...
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Content analysis of Reddit posts about coadministration of selective serotonin reuptake inhibitors and psilocybin mushrooms
RationaleTreatments with the serotonergic psychedelic psilocybin are being investigated for multiple neuropsychiatric disorders. Because many...
