Search
Search Results
-
The mixed legacy of the rat estrous cycle
BackgroundThe rat estrous cycle first characterized by Long and Evans in 1922 profoundly affected the course of endocrine research. Investigators...
-
The Sugen/Hypoxia Rat Model for Pulmonary Hypertension and Right Heart Failure
Pulmonary hypertension (PH) is a devastating disease, characterized by complex remodeling of the pulmonary vasculature. PH is classified into five...
-
Time-Lapse Observation of Cell Dynamics During Angiogenesis Using the Rat Mesentery Culture Model
The ability to track cells and their interactions with other cells during physiological processes offers a powerful tool for scientific discovery. An...
-
Changes of melatonin secretion in the neuropathic pain induced sleep disorder model rat
Chronic pain due to peripheral neuropathy can lead to sleep disorders that significantly worsen the patient's quality of life. Previously, we...
-
Development and Optimization of a Multilayer Rat Purkinje Neuron Culture
Elucidation of the mechanisms involved in neurodegenerative diseases of the cerebellum has been hampered by the lack of robust single cell models to...
-
CoQ10 targeted hippocampal ferroptosis in a status epilepticus rat model
Status epilepticus (SE), the most severe form of epilepsy, leads to brain damage. Uncertainty persists about the mechanisms that lead to the...
-
A consensus protocol for functional connectivity analysis in the rat brain
Task-free functional connectivity in animal models provides an experimental framework to examine connectivity phenomena under controlled conditions...
-
Acute spinal cord injury serum biomarkers in human and rat: a scoping systematic review
Study designScoping systematic review.
ObjectivesTo summarize the available experimental clinical and animal studies for the identification of all...
-
Titanium Dioxide (E171) Induces Toxicity in H9c2 Rat Cardiomyoblasts and Ex Vivo Rat Hearts
Cardiovascular diseases are the leading cause of death worldwide. Food-grade TiO 2 (E171) is the most widely used additive in the food industry....
-
Rat Model of Isoproterenol-Induced Myocardial Injury
Isoproterenol (ISO) administration produces significant biochemical and histological changes including oxidative stress, reactive oxygen species...
-
Detection of in vivo mutagenicity in rat liver samples using error-corrected sequencing techniques
BackgroundMutagenicity, the ability of chemical agents to cause mutations and potentially lead to cancer, is a critical aspect of substance safety...
-
Role of inflammation in a rat model of radiation retinopathy
Radiation retinopathy (RR) is a major side effect of ocular tumor treatment by plaque brachytherapy or proton beam therapy. RR manifests as delayed...
-
Basal release of 6-cyanodopamine from rat isolated vas deferens and its role on the tissue contractility
6-Cyanodopamine is a novel catecholamine released from rabbit isolated heart. However, it is not known whether this catecholamine presents any...
-
Profiling GABA(A) Receptor Subunit Expression in the Hippocampus of PMDD Rat Models Based on TCM Theories
γ-Aminobutyric acid type A receptors (GABAARs) play an important role in cognitive and emotional regulation and are related to the hippocampus....
-
Rat Model of Middle Cerebral Artery Occlusion
Stroke is the third-leading cause of death and the leading cause of acquired adult disability worldwide. Several ischemic stroke models are currently...
-
Characteristics of the Antitumor Effect of Doxorubicin and Pegylated Hyaluronidase on Models of Rat Brain Tumors
Hyaluronidase increases tissue permeability and diffusion of the extracellular fluid by cleaving hyaluronan, the primary component of the...
-
Liquid Chromatography Tandem Mass Spectrometric Method for Quantification of Margetuximab in Rat Plasma and Application to a Pharmacokinetic Study
Margetuximab was approved for the treatment of advanced HER2+ breast cancer. A feasible analytical technique that can measure this drug was...
-
Preoptic and hypothalamic regulation of multi-tiered, chronologically arranged female rat sexual behavior
As in many mammalian behaviors, sexual behavior exhibits structure. Each modular components of the structure, that are linked together over time,...
-
The Extraordinary Biology of the Naked Mole-Rat
This volume focuses on the huge advances in the last 25 years on the use of this animal model for biomedical research (cancer, heart disease and...
-
Baicalein inhibits IL-1β-induced extracellular matrix degradation with decreased MCP-1 expression in primary rat chondrocytes
Baicalein is a flavonoid extracted from the roots of Scutellaria baicalensis and Scutellaria lateriflora . This compound exerts various biochemical...
