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Dorsolateral Prefrontal Cortex Working Memory and Executive Functions
The prefrontal cortex is known to play important roles for performing a variety of higher cognitive functions. Among regions of the prefrontal...
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Dorsolateral Prefrontal Cortex
The prefrontal cortex is known to play an important role in planning and controlling a variety of cognitive functions and in organizing and... -
Timescales of learning in prefrontal cortex
The lateral prefrontal cortex (PFC) in humans and other primates is critical for immediate, goal-directed behaviour and working memory, which are...
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Distributional reinforcement learning in prefrontal cortex
The prefrontal cortex is crucial for learning and decision-making. Classic reinforcement learning (RL) theories center on learning the expectation of...
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Abstract deliberation by visuomotor neurons in prefrontal cortex
During visually guided behavior, the prefrontal cortex plays a pivotal role in mapping sensory inputs onto appropriate motor plans. When the sensory...
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Computational Modeling of the Prefrontal-Cingulate Cortex to Investigate the Role of Coupling Relationships for Balancing Emotion and Cognition
Within the prefrontal-cingulate cortex, abnormalities in coupling between neuronal networks can disturb the emotion-cognition interactions,...
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Transcriptome Analysis and Epigenetics Regulation in the Hippocampus and the Prefrontal Cortex of VPA-Induced Rat Model
Autism spectrum disorders (ASD) are a highly heterogeneous group of neurodevelopmental disorders caused by complex interaction between various genes...
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Attractor dynamics reflect decision confidence in macaque prefrontal cortex
Decisions are made with different degrees of consistency, and this consistency can be linked to the confidence that the best choice has been made....
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Top-down control of vestibular inputs by the dorsolateral prefrontal cortex
The vestibular apparatus provides spatial information on the position of the head in space and with respect to gravity. Low-frequency sinusoidal...
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Laminar Distribution of Cannabinoid Receptor 1 in the Prefrontal Cortex of Nonhuman Primates
Cannabis is an annual herb of the genus Cannabis, with a history of medical use going back thousands of years. However, its abuse causes many...
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Attachment and emotional regulation: examining the role of prefrontal cortex functions, executive functions, and mindfulness in their relationship
Attachment is a prominent area of psychological research, with its relevance linked to executive functions, mindfulness, and emotional regulation....
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Anatomical analyses of collateral prefrontal cortex projections to the basolateral amygdala and the nucleus accumbens core in rats
The basolateral amygdala (BLA) and the nucleus accumbens core (NAcc) share some similar behavioral functions, such as associative learning, Pavlovian...
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Prefrontal Control of Actions and Habits
Habits help to reduce cognitive load and free up resources required for dynamic goal-directed decisions. The prefrontal cortex has been largely... -
Reduced REST Expression in Neural Progenitor Cells, Adult Cortex, and Impaired REST Nuclear Translocation in the Prefrontal Cortex of Ts1Cje Mouse Model of Down Syndrome
AbstractDown syndrome (DS) is a common genetic disorder caused by trisomy of human chromosome 21. DS individuals have neurodevelopmental defects that...
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Do we understand the prefrontal cortex?
Many suggestions have been made as to the functions of the prefrontal (PF) cortex. However, they involve labelling areas using psychological...
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Alcohol-induced damage to the fimbria/fornix reduces hippocampal-prefrontal cortex connection during early abstinence
IntroductionAlcohol dependence is characterized by a gradual reduction in cognitive control and inflexibility to contingency changes. The...
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Sex-specific impacts of prenatal bisphenol A exposure on genes associated with cortical development, social behaviors, and autism in the offspring’s prefrontal cortex
BackgroundRecent studies have shown that prenatal BPA exposure altered the transcriptome profiles of autism-related genes in the offspring’s...
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The Interaction of the Dorsolateral and Ventromedial Prefrontal Cortex During Mind Wandering
Background and AimsMind wandering refers to spontaneously occurring, often disruptive thoughts during an ongoing task or resting state. The...
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Altered connectivity in the cognitive control-related prefrontal cortex in Parkinson’s disease with rapid eye movement sleep behavior disorder
Rapid eye movement sleep behavior disorder (RBD) frequently occurs in Parkinson’s disease (PD), however, the exact pathophysiological mechanism is...
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Autophagy in Neurons of the Prefrontal Cortex and Hippocampus of Rats after Trimethyltin Chloride Intoxication
Ultrastructural studies of the hippocampus and the prefrontal cortex of rats were performed 7, 30, and 50 days after their damage by neurotoxicant...