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  1. Dorsolateral Prefrontal Cortex Working Memory and Executive Functions

    The prefrontal cortex is known to play important roles for performing a variety of higher cognitive functions. Among regions of the prefrontal...

    Shintaro Funahashi in Brain Science
    Book 2022
  2. Dorsolateral Prefrontal Cortex

    The prefrontal cortex is known to play an important role in planning and controlling a variety of cognitive functions and in organizing and...
    Shintaro Funahashi in Dorsolateral Prefrontal Cortex
    Chapter 2022
  3. Timescales of learning in prefrontal cortex

    The lateral prefrontal cortex (PFC) in humans and other primates is critical for immediate, goal-directed behaviour and working memory, which are...

    Jacob A. Miller, Christos Constantinidis in Nature Reviews Neuroscience
    Article 27 June 2024
  4. Distributional reinforcement learning in prefrontal cortex

    The prefrontal cortex is crucial for learning and decision-making. Classic reinforcement learning (RL) theories center on learning the expectation of...

    Timothy H. Muller, James L. Butler, ... Steven W. Kennerley in Nature Neuroscience
    Article Open access 10 January 2024
  5. Abstract deliberation by visuomotor neurons in prefrontal cortex

    During visually guided behavior, the prefrontal cortex plays a pivotal role in mapping sensory inputs onto appropriate motor plans. When the sensory...

    Julie A. Charlton, Robbe L. T. Goris in Nature Neuroscience
    Article Open access 29 April 2024
  6. Computational Modeling of the Prefrontal-Cingulate Cortex to Investigate the Role of Coupling Relationships for Balancing Emotion and Cognition

    Within the prefrontal-cingulate cortex, abnormalities in coupling between neuronal networks can disturb the emotion-cognition interactions,...

    Jinzhao Wei, Licong Li, ... Xiuling Liu in Neuroscience Bulletin
    Article 13 June 2024
  7. Transcriptome Analysis and Epigenetics Regulation in the Hippocampus and the Prefrontal Cortex of VPA-Induced Rat Model

    Autism spectrum disorders (ASD) are a highly heterogeneous group of neurodevelopmental disorders caused by complex interaction between various genes...

    Lei Chen, Qiang Fu, ... Yong Cheng in Molecular Neurobiology
    Article 17 August 2023
  8. Attractor dynamics reflect decision confidence in macaque prefrontal cortex

    Decisions are made with different degrees of consistency, and this consistency can be linked to the confidence that the best choice has been made....

    Siyu Wang, Rossella Falcone, ... Bruno B. Averbeck in Nature Neuroscience
    Article 05 October 2023
  9. Top-down control of vestibular inputs by the dorsolateral prefrontal cortex

    The vestibular apparatus provides spatial information on the position of the head in space and with respect to gravity. Low-frequency sinusoidal...

    Brendan McCarthy, Sudipta Datta, ... Vaughan G. Macefield in Experimental Brain Research
    Article Open access 30 October 2023
  10. Laminar Distribution of Cannabinoid Receptor 1 in the Prefrontal Cortex of Nonhuman Primates

    Cannabis is an annual herb of the genus Cannabis, with a history of medical use going back thousands of years. However, its abuse causes many...

    Yingying Han, Qianyu Dong, ... Chaolin Ma in Molecular Neurobiology
    Article 07 December 2023
  11. Attachment and emotional regulation: examining the role of prefrontal cortex functions, executive functions, and mindfulness in their relationship

    Attachment is a prominent area of psychological research, with its relevance linked to executive functions, mindfulness, and emotional regulation....

    Nesrin Hisli Sahin, Anthony F. Tasso, Murat Guler in Cognitive Processing
    Article 27 June 2023
  12. Anatomical analyses of collateral prefrontal cortex projections to the basolateral amygdala and the nucleus accumbens core in rats

    The basolateral amygdala (BLA) and the nucleus accumbens core (NAcc) share some similar behavioral functions, such as associative learning, Pavlovian...

    Cheng-Wei Shih, Chun-hui Chang in Brain Structure and Function
    Article 01 November 2023
  13. Prefrontal Control of Actions and Habits

    Habits help to reduce cognitive load and free up resources required for dynamic goal-directed decisions. The prefrontal cortex has been largely...
    Karly M. Turner in Habits
    Chapter 2024
  14. Reduced REST Expression in Neural Progenitor Cells, Adult Cortex, and Impaired REST Nuclear Translocation in the Prefrontal Cortex of Ts1Cje Mouse Model of Down Syndrome

    Abstract

    Down syndrome (DS) is a common genetic disorder caused by trisomy of human chromosome 21. DS individuals have neurodevelopmental defects that...

    Chong-Teik Lim, Xin-Jieh Lam, ... King-Hwa Ling in Neurochemical Journal
    Article 01 March 2024
  15. Do we understand the prefrontal cortex?

    Many suggestions have been made as to the functions of the prefrontal (PF) cortex. However, they involve labelling areas using psychological...

    Richard E. Passingham, Hakwan Lau in Brain Structure and Function
    Article 08 November 2022
  16. Alcohol-induced damage to the fimbria/fornix reduces hippocampal-prefrontal cortex connection during early abstinence

    Introduction

    Alcohol dependence is characterized by a gradual reduction in cognitive control and inflexibility to contingency changes. The...

    Laura Pérez-Cervera, Silvia De Santis, ... Santiago Canals in Acta Neuropathologica Communications
    Article Open access 21 June 2023
  17. Sex-specific impacts of prenatal bisphenol A exposure on genes associated with cortical development, social behaviors, and autism in the offspring’s prefrontal cortex

    Background

    Recent studies have shown that prenatal BPA exposure altered the transcriptome profiles of autism-related genes in the offspring’s...

    Songphon Kanlayaprasit, Thanit Saeliw, ... Tewarit Sarachana in Biology of Sex Differences
    Article Open access 15 May 2024
  18. The Interaction of the Dorsolateral and Ventromedial Prefrontal Cortex During Mind Wandering

    Background and Aims

    Mind wandering refers to spontaneously occurring, often disruptive thoughts during an ongoing task or resting state. The...

    Vahid Nejati, Bahar Zamiran, Michael A. Nitsche in Brain Topography
    Article 18 May 2023
  19. Altered connectivity in the cognitive control-related prefrontal cortex in Parkinson’s disease with rapid eye movement sleep behavior disorder

    Rapid eye movement sleep behavior disorder (RBD) frequently occurs in Parkinson’s disease (PD), however, the exact pathophysiological mechanism is...

    Jinjing Liu, Xiaoya Zou, ... Oumei Cheng in Brain Imaging and Behavior
    Article 18 September 2023
  20. Autophagy in Neurons of the Prefrontal Cortex and Hippocampus of Rats after Trimethyltin Chloride Intoxication

    Ultrastructural studies of the hippocampus and the prefrontal cortex of rats were performed 7, 30, and 50 days after their damage by neurotoxicant...

    I. B. Mikheeva, E. V. Pershina, ... V. I. Arkhipov in Bulletin of Experimental Biology and Medicine
    Article 01 September 2022
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