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Immunohistochemical field parcellation of the human hippocampus along its antero-posterior axis
The primate hippocampus includes the dentate gyrus, cornu ammonis (CA), and subiculum. CA is subdivided into four fields (CA1-CA3, plus CA3h/hilus of...
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Static and dynamic functional connectivity variability of the anterior-posterior hippocampus with subjective cognitive decline
BackgroundSubjective cognitive decline (SCD) is a putative Alzheimer’s disease (AD) precursor without objective neuropsychological deficits. The...
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Comparative metabolic profiling of posterior parietal cortex, amygdala, and hippocampus in conditioned fear memory
Fear conditioning and retrieval are suitable models to investigate the biological basis of various mental disorders. Hippocampus and amygdala neurons...
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Social navigation modulates the anterior and posterior hippocampal circuits in the resting brain
Social navigation is a dynamic and complex process that requires the collaboration of multiple brain regions. However, the neural networks for...
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Non-invasive temporal interference electrical stimulation of the human hippocampus
Deep brain stimulation (DBS) via implanted electrodes is used worldwide to treat patients with severe neurological and psychiatric disorders....
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Photothrombotic Model to Create an Infarct in the Hippocampus
Photothrombosis is one of the techniques available to reproduce ischemic injuries in animal models. Most of the studies that use photothrombosis...
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The functional and structural changes in the hippocampus of COVID-19 patients
Since the hippocampus is predominantly susceptible to injuries caused by COVID-19, there are increasing data indicating the likelihood of...
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Neural Correlates of Spatial Navigation in Primate Hippocampus
The hippocampus has been extensively implicated in spatial navigation in rodents and more recently in bats. Numerous studies have revealed that...
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Hippocampus: Molecular, Cellular, and Circuit Features in Anxiety
Anxiety disorders are currently a major psychiatric and social problem, the mechanisms of which have been only partially elucidated. The hippocampus...
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Keratinocyte-Derived Cytokine in the Hippocampus Disrupts Extinction of Conditioned Fear Memory in Tumor-Bearing Mice
While patients with cancer show a higher prevalence of psychiatric disorders than the general population, the mechanism underlying this interaction...
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Deep convolutional neural network for hippocampus segmentation with boundary region refinement
Accurately segmenting the hippocampus from magnetic resonance (MR) brain images is a crucial step in studying brain disorders. However, this task is...
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Disfunction of dorsal raphe nucleus-hippocampus serotonergic-HTR3 transmission results in anxiety phenotype of Neuroplastin 65-deficient mice
Anxiety disorders are the most common psychiatric condition, but the etiology of anxiety disorders remains largely unclear. Our previous studies have...
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Different posterior hippocampus and default mode network modulation in young APOE ε4 carriers: a functional connectome-informed phenotype longitudinal study
To determine the functional connectome change pattern based on subregions of the hippocampus in young APOEε4 carriers during a 3-year follow-up. All...
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Hippocampus-centred grey matter covariance networks predict the development and reversion of mild cognitive impairment
BackgroundMild cognitive impairment (MCI) has been thought of as the transitional stage between normal ageing and Alzheimer’s disease, involving...
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The Impact of Cerebral Ischemia on Antioxidant Enzymes Activity and Neuronal Damage in the Hippocampus
Cerebral ischemia and subsequent reperfusion, leading to reduced blood supply to specific brain areas, remain significant contributors to...
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Intermittent Fasting Improves Social Interaction and Decreases Inflammatory Markers in Cortex and Hippocampus
Autism spectrum disorder (ASD) is a psychiatric condition characterized by reduced social interaction, anxiety, and stereotypic behaviors related to...
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Mechanisms of Functioning of the Connectome Including the Neocortex, Hippocampus, Basal Ganglia, Cerebellum, and Thalamus
Possible mechanisms of the interactions of neuron functioning in the connectome including topographically connected areas of the neocortex,...
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GRK5 Deficiency in the Hippocampus Leads to Cognitive Impairment via Abnormal Microglial Alterations
GRK5 is a member of the G protein-coupled receptor (GPCR) kinase family and is closely associated with heart and nervous system disease. It has been...
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Ablated Sonic Hedgehog Signaling in the Dentate Gyrus of the Dorsal and Ventral Hippocampus Impairs Hippocampal-Dependent Memory Tasks and Emotion in a Rat Model of Depression
Specific memory processes and emotional aberrations in depression can be attributed to the different dorsal–ventral regions of the hippocampus....
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Hippocampus-Dependent Learning Deficit Does Not Correlate with Suppression of Long-Term Post-Tetanic Potentiation by Systemic Blockade of NMDA Receptors
Learning and behavior were more sensitive than LTP-like plasticity to blockade of NMDA receptors (NMDAr). I.p. and intraventricular injections of...
