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Plant-Derived Extracellular Nanovesicles for Disease Therapy
Natural plants and traditional Chinese medicines (TCMs) have been widely used throughout human history and are available in many pharmaceutical... -
Plant-derived exosome-like nanoparticles for microRNA delivery in cancer treatment
Plant-derived exosome-like nanoparticles (PELNs) are natural nanocarriers and effective delivery systems for plant microRNAs (miRNAs). These...
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Protective Effects of Plant-Derived Compounds Against Traumatic Brain Injury
Inflammation in the nervous system is one of the key features of many neurodegenerative diseases. It is increasingly being identified as a critical...
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Impact of Plant-Derived Compounds on Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a fatal illness characterized by progressive motor neuron degeneration. Conventional therapies for ALS are...
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Meta-analysis of the anti-oxidative and anti-inflammatory effects of hypoglycaemic plant-derived medicines
BackgroundThe pivotal role of oxidative stress and inflammation in the pathophysiology of type 2 diabetes mellitus (T2DM) has been firmly...
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Recent Approaches to Combat Toxoplasma Gondii with Plant-Derived Alternatives
Toxoplasmosis is considered as one of the widely distributed and predominant parasitic ailments. This Zoonotic infection caused by Toxoplasma gondii... -
In vitro combination effects of plant-derived quercetin with synthetic bicalutamide on prostate cancer and normal cell lines: in silico comparison
Prostate cancer is the second most frequent and the fifth greatest cause of death in men. Although diet has been connected to the prevalence of...
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Effect of Plant-Derived Immunomodulators on the Immune System
To regulate several immunological changes in the prevention of diseases, immunomodulators are helpful compounds which are derived naturally from... -
The secretome from human-derived mesenchymal stem cells augments the activity of antitumor plant extracts in vitro
Cancer is understood as a multifactorial disease that involve multiple cell types and phenotypes in the tumor microenvironment (TME). The components...
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Robust induction of functional humoral response by a plant-derived Coronavirus-like particle vaccine candidate for COVID-19
Despite the success of existing COVID-19 vaccine platforms, the persistent limitations in global deployment of vaccines and waning immunity exhibited...
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Synthesis of Novel Plant-Derived Encapsulated Radiolabeled Compounds for the Diagnosis of Parkinson’s Disease and the Evaluation of Biological Effects with In Vitro/In Vivo Methods
Parkinson’s disease (PD) is a neurodegenerative disorder that affects millions of individuals globally. It is characterized by the loss of...
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Immune-instructive copolymer scaffolds using plant-derived nanoparticles to promote bone regeneration
BackgroundAge-driven immune signals cause a state of chronic low-grade inflammation and in consequence affect bone healing and cause challenges for...
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Soil-derived bacteria endow Camellia weevil with more ability to resist plant chemical defense
BackgroundHerbivorous insects acquire their gut microbiota from diverse sources, and these microorganisms play significant roles in insect hosts’...
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Searching for plant-derived antivirals against dengue virus and Zika virus
BackgroundThe worldwide epidemics of diseases as dengue and Zika have triggered an intense effort to repurpose drugs and search for novel antivirals...
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Myricetin: a potential plant-derived anticancer bioactive compound—an updated overview
The globe is currently confronting a global fight against the deadliest cancer sickness. Chemotherapy, hormonal therapy, surgery, and radiation...
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Rheumatoid arthritis—recent advances in pathogenesis and the anti-inflammatory effect of plant-derived COX inhibitors
The majority of people with autoimmune disorders, including those with rheumatoid arthritis, osteoarthritis, and tendonitis report pain, stiffness,...
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Antithrombotic and antiplatelet effects of plant-derived compounds: a great utility potential for primary, secondary, and tertiary care in the framework of 3P medicine
Thromboembolism is the third leading vascular disease, with a high annual incidence of 1 to 2 cases per 1000 individuals within the general...
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Plant-Derived Human Vaccines: Recent Developments
The idea of producing vaccines in plants originated in the late 1980s. Initially, it was contemplated that this notion could facilitate the concept...
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An update on the bioactivities and health benefits of two plant-derived lignans, phyllanthin and hypophyllanthin
Polyphenols are notable phytochemicals mostly found in plant-based foods, with many reported health benefits. Only limited information is available...
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Delivery Systems of Plant-Derived Antimicrobials
The use of essential oils as antimicrobial agents is widely applied in medical field, pharmaceutical industry, and food preservation. However,...