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Oxytocin in Lactation and Parturition
This chapter outlines the physiology of the oxytocin system as relevant to our understanding of the milk-ejection reflex, and of the control of... -
Kisspeptin neuron projections to oxytocin neurons are not necessary for parturition in the mouse
Oxytocin is synthesized by hypothalamic supraoptic nucleus (SON) and paraventricular nucleus (PVN) neurons and is released from the posterior...
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IL-33/ST2 axis of human amnion fibroblasts participates in inflammatory reactions at parturition
BackgroundInflammation of the fetal membranes is an indispensable event of labor onset at both term and preterm birth. Interleukin-33 (IL-33) is...
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Amnion-derived serum amyloid A1 participates in sterile inflammation of fetal membranes at parturition
ObjectivesSterile inflammation of fetal membranes is an indispensable event of normal parturition. However, triggers of sterile inflammation are not...
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Genetic effects on the timing of parturition and links to fetal birth weight
The timing of parturition is crucial for neonatal survival and infant health. Yet, its genetic basis remains largely unresolved. We present a...
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The Effect of B9 and B12 Vitamins Deficiency on Hypomethylation of MMP-9 gene Promoter Among Women With Preterm Parturition
Preterm birth is one of the problems that pregnant women may encounter during pregnancy. Over-expression of Matrix metalloproteinases (MMPs) has the...
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Basic Protocols for the Study of Maternal Behavior in Rabbits
Maternal behavior in rabbits is unusual among mammals. During pregnancy, the doe builds a nest and after parturition the only maternal behavior... -
Distinct expression patterns of aquaporin 3 and 5 in ductal and alveolar epithelial cells in mouse mammary glands before and after parturition
Milk osmolarity maintains an isotonic status for suckling infants during lactation. However, it remains unclear how the water content in milk is...
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Placental TLR recognition of salivary and subgingival microbiota is associated with pregnancy complications
BackgroundPre-term birth, the leading cause of neonatal mortality, has been associated with maternal periodontal disease and the presence of oral...
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Characterisation of the koala (Phascolarctos cinereus) pouch microbiota in a captive population reveals a dysbiotic compositional profile associated with neonatal mortality
BackgroundCaptive koala breeding programmes are essential for long-term species management. However, breeding efficacy is frequently impacted by high...
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The Onset of Maternal Behavior in Sheep and Goats: Endocrine, Sensory, Neural, and Experiential Mechanisms
In sheep and goats, the onset of maternal behavior at parturition is characterized by a first phase called maternal responsiveness during which the... -
Culture and Maintenance of Immune Cells to Model Innate Immune Status at the Feto-maternal Interface
The inflammatory process leading to human labor is mostly facilitated by immune cells, which can be studied by isolating and characterizing primary... -
Immersed in a reservoir of potential: amniotic fluid-derived extracellular vesicles
This review aims to encapsulate the current knowledge in extracellular vesicles extracted from amniotic fluid and amniotic fluid derived stem/stromal...
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Metabolic profiling in periparturient dairy cows and its relation with metabolic diseases
ObjectivePeriparturient period is associated with multiple changes including serum concentration of macro minerals and drop in feed intake....
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Emotions Studied by Imaging of the Human Brain: The Somatic and Emotional Motor Systems
The brain has only two goals, survival of the individual and survival of the species. One of the most important tools to accomplish these goals is... -
Basic Protocols to Study Parental Behavior in Rats
Maternal care is an affiliative, motivated, and complex social behavior that has been conserved through evolution to ensure the survival of the... -
Gestational Fisetin Exerts Neuroprotection by Regulating Mitochondria-Directed Canonical Wnt Signaling, BBB Integrity, and Apoptosis in Prenatal VPA-Induced Rodent Model of Autism
AbstractEmbryonic valproic acid (VPA) has been considered a potential risk factor for autism. Majority of studies indicated that targeting...
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Feto-Maternal Interface Organ-on-Chip: A New Technology to Study Ascending Infection
Modeling human pregnancy is challenging as two subjects, the mother and fetus, must be evaluated in tandem. To understand pregnancy, parturition, and... -
Q fever immunology: the quest for a safe and effective vaccine
Q fever is an infectious zoonotic disease, caused by the Gram-negative bacterium Coxiella burnetii . Transmission occurs from livestock to humans...