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White matter abnormalities in paediatric obsessive–compulsive disorder: a systematic review of diffusion tensor imaging studies
Microstructural alterations in white matter are evident in obsessive–compulsive disorder (OCD) both in adult and paediatric populations. Paediatric...
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A biophysical model for dopamine modulating working memory through reward system in obsessive–compulsive disorder
Dopamine modulates working memory in the prefrontal cortex (PFC) and is crucial for obsessive–compulsive disorder (OCD). However, the mechanism is...
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Epigenetic modifications and obsessive–compulsive disorder: what do we know?
Obsessive–Compulsive Disorder (OCD) is a chronic, severe disabling neuropsychiatric disorder whose pathophysiology is not yet well defined....
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Neurobiology of Obsessive–Compulsive Disorder from Genes to Circuits: Insights from Animal Models
Obsessive-compulsive disorder (OCD) is a chronic, severe psychiatric disorder that has been ranked by the World Health Organization as one of the...
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Serum Erythropoietin and Ischemic-Modified Albumin Levels in Adolescents with Obsessive–Compulsive Disorder
Erythropoietin (EPO) has neuroprotective effects by increasing oxidative stress resistance and stabilizing redox balance. Ischemic-modified albumin...
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MMP-9 and TIMP-1 Levels in Children and Adolescents with Obsessive Compulsive Disorder
AbstractThis study aimed to evaluate matrix metalloproteinase-9(MMP-9), tissue inhibitors of matrix metalloproteinases (TIMP-1) and the ratio of...
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Cerebellar Microstructural Abnormalities in Obsessive–Compulsive Disorder (OCD): a Systematic Review of Diffusion Tensor Imaging Studies
Previous neuroimaging studies have suggested that obsessive–compulsive disorder (OCD) is associated with altered resting-state functional...
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Targeting inflammatory signaling in obsessive compulsive disorder: a promising approach
Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder. Approximately, around 2% to 3% percent of the general population experience...
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Disruption of neural periodicity predicts clinical response after deep brain stimulation for obsessive-compulsive disorder
Recent advances in surgical neuromodulation have enabled chronic and continuous intracranial monitoring during everyday life. We used this...
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Evaluation of Paraoxonase, Arylesterase, Dipeptidyl Peptidase-IV, Oxidative Stress, and Oxidative DNA Damage in Patients with Obsessive-Compulsive Disorder
AbstractSome findings have emerged from the field of oxidative stress in patients with psychiatric disorders. These date also state that oxidative...
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Biomarkers in Obsessive-Compulsive Spectrum Disorders
Obsessive-compulsive disorder (OCD) is characterized by recurrent and persistent thoughts, urges, or images that result in anxiety or distress... -
Obsessive-Compulsive Disorder, PANDAS, and Tourette Syndrome: Immuno-inflammatory Disorders
In the last years, much focus has been given to the possible role of inflammatory and immunologic alterations in the pathophysiology of... -
Obsessive Compulsive Disorders
Obsessive-compulsive disorder (OCD) is a common and debilitating psychiatric condition. Relatively little, however, is understood about the etiology... -
Exploring the structure of the university-students obsessive–compulsive tendency scale in Iranian university students: a network analysis study
IntroductionA risk factor for developing obsessive–compulsive disorder (OCD) in non-clinical samples is obsessive–compulsive tendencies (OCT). An OCT...
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Cortical thickness and surface area in patients with obsessive compulsive disorder and their unaffected siblings
Little is known about the underlying neurobiological mechanisms in patients with obsessive-compulsive disorder (OCD). We aimed to examine cortical...
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A computational network dynamical modeling for abnormal oscillation and deep brain stimulation control of obsessive–compulsive disorder
Obsessive–compulsive disorder (OCD) is associated with multi-nodal abnormalities in brain networks, characterized by recurrent intrusive thoughts...
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Granisetron-mediated augmentation of sertraline therapeutic effect in obsessive-compulsive disorder: a double-blind placebo-controlled, randomized clinical trial
BackgroundMedications currently recommended for the treatment of Obsessive-Compulsive Disorder (OCD) usually relieve the severity of symptoms by as...
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Obsessive-compulsive symptoms and resting-state functional characteristics in pre-adolescent children from the general population
While functional brain characteristics of obsessive-compulsive disorder have been extensively studied, literature on network topology and subnetwork...
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Nutritional Deficiencies in Obsessive-Compulsive Disorder and Possible Treatment Interventions
Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder characterized by intrusive distressing thoughts, images, or impulses (obsessions)...