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Neuroinflammation
Neuroinflammation is closely intertwined with the release of pro-inflammatory cytokines by microglia and astrocytes. These cytokines have a double...
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Purinergic Signaling in Neuroinflammation
Neuroinflammation is a process induced by the innate immune system and involves the activation of resident immune cells of the CNS, such as...
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Neuroinflammation in Alzheimer’s Disease
Alzheimer’s disease (AD) is one of the significant progressive disorders of the brain, which lead to the destruction of memory and cognitive power in...
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A Potential Role for Neuroinflammation in ADHD
Attention deficit hyperactivity disorder (ADHD) is a neurobehavioural disorder in children and adolescents. Although increases in oxidative stress...
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Ripks and Neuroinflammation
Neuroinflammation is an immune response in the central nervous system and poses a significant threat to human health. Studies have shown that the...
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Promising Markers of Neuroinflammation in Schizophrenia
Abstract —There is no single model for the pathogenesis of schizophrenia, but neuroinflammation is considered a key mechanism in the development of...
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PET Imaging to Measure Neuroinflammation In Vivo
This paper provides an overview of the role of neuroinflammation in Alzheimer’s disease and other neurodegenerative diseases, highlighting the...
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Neuroinflammation in Huntington’s Disease
Huntington’s disease (HD) is a debilitating inherited neurodegenerative disorder characterized by motor, cognitive and psychiatric deficits....
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GPR34 senses demyelination to promote neuroinflammation and pathologies
Sterile neuroinflammation is a major driver of multiple neurological diseases. Myelin debris can act as an inflammatory stimulus to promote...
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Molecular Imaging of Neuroinflammation in Alzheimer’s Disease and Mild Cognitive Impairment
Alzheimer’s disease (AD) is the most prevalent neurocognitive disorder. Due to the ineffectiveness of treatments targeting the amyloid cascade,...
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Mitochondrial stress: a key role of neuroinflammation in stroke
Stroke is a clinical syndrome characterized by an acute, focal neurological deficit, primarily caused by the occlusion or rupture of cerebral blood...
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Acupuncture for Counteracting P2X4 and P2X7 Receptor Involvement in Neuroinflammation
Neuroinflammation refers to an inflammatory change within the brain or spinal cord, mainly characterized by the activation/invasion of the following...
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Neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis
As one of most common and severe mental disorders, major depressive disorder (MDD) significantly increases the risks of premature death and other...
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Neuroinflammation in Obese Children
Obesity is associated with chronic persistent inflammation due to a pool of tissue macrophages that can penetrate the blood—brain barrier and cause...
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Human iPSC-derived glia models for the study of neuroinflammation
Neuroinflammation is a complex biological process that plays a significant role in various brain disorders. Microglia and astrocytes are the key cell...
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Exercise mimetics: a novel strategy to combat neuroinflammation and Alzheimer’s disease
Neuroinflammation is a pathological hallmark of Alzheimer’s disease (AD), characterized by the stimulation of resident immune cells of the brain and...
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Neuroinflammation increases oxygen extraction in a mouse model of Alzheimer’s disease
BackgroundNeuroinflammation, impaired metabolism, and hypoperfusion are fundamental pathological hallmarks of early Alzheimer’s disease (AD)....
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Neuroinflammation and Microglial Activation in Schizophrenia: An Overview
Schizophrenia has been classified recently to be initiated as a neuroinflammatory disorder that may upgrade later into neurodegenerative one. There...
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Post-traumatic Stress Disorder: Focus on Neuroinflammation
Post-traumatic stress disorder (PTSD), gaining increasing attention, is a multifaceted psychiatric disorder that occurs following a stressful or...
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Dimethyl fumarate improves cognitive impairment and neuroinflammation in mice with Alzheimer’s disease
BackgroundNeuroinflammation substantially contributes to the pathology of Alzheimer’s disease (AD), the most common form of dementia. Studies have...
