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Differences in the organization of the primary motor cortex in people with and without low back pain and associations with motor control and sensory tests
Differences in organization of the primary motor cortex and altered trunk motor control (sensing, processing and motor output) have been reported in...
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Triple dissociation of visual, auditory and motor processing in mouse primary visual cortex
Primary sensory cortices respond to crossmodal stimuli—for example, auditory responses are found in primary visual cortex (V1). However, it remains...
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Underlying interactive neural mechanism of motor learning governed by the cerebellum, the basal ganglia, and motor/sensory cortex: a review from theoretical perspective
The pursuit of effective motion rehabilitation devices has been a prominent focus of research in recent decades. However, the efficacy of such...
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Modulation of intracortical circuits in primary motor cortex during automatic action tendencies
Humans display automatic action tendencies toward emotional stimuli, showing faster automatic behavior (i.e., approaching a positive stimulus and...
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Unsupervised machine learning identifies distinct ALS molecular subtypes in post-mortem motor cortex and blood expression data
Amyotrophic lateral sclerosis (ALS) displays considerable clinical and genetic heterogeneity. Machine learning approaches have previously been...
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Motor cortex excitability in chronic low back pain
Chronic pain is associated with dysfunctional cortical excitability. Research has identified altered intracortical motor cortex excitability in...
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Evoked EEG Responses to TMS Targeting Regions Outside the Primary Motor Cortex and Their Test–Retest Reliability
Transcranial magnetic stimulation (TMS)–evoked electroencephalography (EEG) potentials (TEPs) provide unique insights into cortical excitability and...
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Multitask representations in the human cortex transform along a sensory-to-motor hierarchy
Human cognition recruits distributed neural processes, yet the organizing computational and functional architectures remain unclear. Here, we...
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Intracortical facilitation and inhibition in human primary motor cortex during motor skill acquisition
The primary motor cortex (M1) is critical for movement execution, but its role in motor skill acquisition remains elusive. Here, we examine the role...
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Novel rAAV vector mediated intrathecal HGF delivery has an impact on neuroimmune modulation in the ALS motor cortex with TDP-43 pathology
Recombinant adeno-associated virus (rAAV)-based gene therapies offer an immense opportunity for rare diseases, such as amyotrophic lateral sclerosis...
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From Parametric Representation to Dynamical System: Shifting Views of the Motor Cortex in Motor Control
In contrast to traditional representational perspectives in which the motor cortex is involved in motor control via neuronal preference for kinetics...
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Testing spasticity mechanisms in chronic stroke before and after intervention with contralesional motor cortex 1 Hz rTMS and physiotherapy
BackgroundPrevious studies showed that repetitive transcranial magnetic stimulation (rTMS) reduces spasticity after stroke. However, clinical...
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Motor cortex excitability is reduced during freezing of upper limb movement in Parkinson’s disease
Whilst involvement of the motor cortex in the phenomenon of freezing in Parkinson’s disease has been previously suggested, few empiric studies have...
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Dynamic causal modeling analysis reveals the modulation of motor cortex and integration in superior temporal gyrus during multisensory speech perception
The processing of speech information from various sensory modalities is crucial for human communication. Both left posterior superior temporal gyrus...
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The Secondary Motor Cortex-striatum Circuit Contributes to Suppressing Inappropriate Responses in Perceptual Decision Behavior
The secondary motor cortex (M2) encodes choice-related information and plays an important role in cue-guided actions. M2 neurons innervate the dorsal...
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Local Administrations of Iron Oxide Nanoparticles in the Prefrontal Cortex and Caudate Putamen of Rats Do Not Compromise Working Memory and Motor Activity
Iron oxide nanoparticles (IONPs) have come into focus for their use in medical applications although possible health risks for humans, especially in...
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Discernible effects of tDCS over the primary motor and posterior parietal cortex on different stages of motor learning
Implicit motor learning and memory involve complex cortical and subcortical networks. The induction of plasticity in these network components via...
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Hypohydration alters pre-frontal cortex haemodynamics, but does not impair motor learning
It is unknown how hypohydration influences fine motor performance training and motor learning. Here, 30 participants (aged 19–46 years) were randomly...
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Motor training is improved by concurrent application of slow oscillating transcranial alternating current stimulation to motor cortex
Physical exercise and neurorehabilitation involve repetitive training that can induce changes in motor performance arising from neuroplasticity....
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Knockdown of Astrocytic Monocarboxylate Transporter 4 in the Motor Cortex Leads to Loss of Dendritic Spines and a Deficit in Motor Learning
Monocarboxylate transporters (MCTs) shuttle molecules, including L-lactate, involved in metabolism and cell signaling of the central nervous system....
