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  1. Independent inhibitory control mechanisms for aggressive motivation and action

    Social behaviors often consist of a motivational phase followed by action. Here we show that neurons in the ventromedial hypothalamus ventrolateral...

    Tomohito Minakuchi, Eartha Mae Guthman, ... Annegret L. Falkner in Nature Neuroscience
    Article 12 February 2024
  2. Sex-dependent effects of acute stress in adolescence or adulthood on appetitive motivation

    Rationale

    Intensely stressful experiences can lead to long-lasting changes in appetitive and aversive behaviors. In humans, post-traumatic stress...

    Rifka C. Derman, K. Matthew Lattal in Psychopharmacology
    Article 16 May 2024
  3. Sexual Incentive Motivation

    Motivation can be described as the processes that activate, direct, and determine the persistence of goal-directed behavior. A certain level of...
    Patty T. Huijgens, Roy Heijkoop, Eelke M. S. Snoeren in Animal Models of Reproductive Behavior
    Protocol 2023
  4. Motivation-related influences on fNIRS signals during walking exercise: a permutation entropy approach

    Cortical activity is typically indexed by analyzing functional near-infrared spectroscopy (fNIRS) signals in terms of the mean (e.g., mean oxygenated...

    Sarah M. Schwab, Dalton Cooper, ... Pierce Boyne in Experimental Brain Research
    Article 21 September 2023
  5. A neural substrate of sex-dependent modulation of motivation

    While there is emerging evidence of sex differences in decision-making behavior, the neural substrates that underlie such differences remain largely...

    Julia Cox, Adelaide R. Minerva, ... Ilana B. Witten in Nature Neuroscience
    Article 16 January 2023
  6. Sex differences in the social motivation of rats: Insights from social operant conditioning, behavioural economics, and video tracking

    Background

    Social behaviour plays a key role in mental health and wellbeing, and developing greater understanding of mechanisms underlying social...

    Joel S Raymond, Simone Rehn, ... Michael T Bowen in Biology of Sex Differences
    Article Open access 19 July 2024
  7. Uncovering the neurophysiology of mood, motivation and behavioral symptoms in Parkinson’s disease through intracranial recordings

    Neuropsychiatric mood and motivation symptoms (depression, anxiety, apathy, impulse control disorders) in Parkinson’s disease (PD) are highly...

    Lucia Ricciardi, Matthew Apps, Simon Little in npj Parkinson's Disease
    Article Open access 21 September 2023
  8. Emotion, motivation, decision-making, the orbitofrontal cortex, anterior cingulate cortex, and the amygdala

    The orbitofrontal cortex and amygdala are involved in emotion and in motivation, but the relationship between these functions performed by these...

    Edmund T. Rolls in Brain Structure and Function
    Article Open access 13 May 2023
  9. Publics’ knowledge of, attitude to and motivation towards health-related genomics: a scoping review

    The use of genomic data in research and genomic information in clinical care is increasing as technologies advance and sequencing costs decrease....

    Angela Pearce, Lucas A. Mitchell, ... Bronwyn Terrill in European Journal of Human Genetics
    Article Open access 06 February 2024
  10. Prediction of cervical cancer screening: application of the information-motivation-behavioral skills model

    Introduction

    Screening is an effective method for preventing cervical cancer. The present study aimed to determine the predictability of cervical...

    Marzieh Ghasemi, Mitra Savabi-Esfahani, ... Mohammad Satari in BMC Cancer
    Article Open access 19 March 2024
  11. Early resource scarcity alters motivation for natural rewards in a sex- and reinforcer-dependent manner

    Rationale

    Early life adversity impacts reward-related behaviors, including reward seeking for drugs of abuse. However, the effects of early stress on...

    Alexia V. Williams, James Flowers, ... Debra A. Bangasser in Psychopharmacology
    Article 27 October 2022
  12. Effect of a short video on patients’ motivation for dose reduction or cessation of hypnotics

    Recently, addiction to regular doses of hypnotics has become a problem. While many patients report a desire to reduce their dosage, many do not agree...

    Misato Amagai, Motohiro Ozone, ... Masahiro Shigeta in Sleep and Biological Rhythms
    Article Open access 27 January 2023
  13. Obese-associated gut microbes and derived phenolic metabolite as mediators of excessive motivation for food reward

    Background

    Excessive hedonic consumption is one of the main drivers for weight gain. Identifying contributors of this dysregulation would help to...

    Alice de Wouters d’Oplinter, Marko Verce, ... Amandine Everard in Microbiome
    Article Open access 28 April 2023
  14. Cocaine-induced plasticity, motivation, and cue responsivity do not differ in obesity-prone vs obesity-resistant rats; implications for food addiction

    Rationale

    Compared to obesity-resistant rats, obesity-prone rats consume more food, work harder to obtain food, show greater motivational responses to...

    Anish A. Saraswat, Lauren G. Longyear, ... Carrie R. Ferrario in Psychopharmacology
    Article Open access 18 February 2023
  15. Are the main effects of the will to exist, live, survive and fight on optimizing executive function due to its optimizing self-motivation? A longitudinal study

    The study aims to identify the mechanisms underlying the findings that will to exist, live, survive and fight (WTELS-F) optimizes executive...

    Ibrahim Aref Kira, Hanaa Shuwiekh in Cognitive Processing
    Article 17 February 2023
  16. α-Dystrobrevin knockout mice have increased motivation for appetitive reward and altered brain cannabinoid receptor 1 expression

    α-Dystrobrevin (α-DB) is a major component of the dystrophin-associated protein complex (DAPC). Knockout (KO) of α-DB in the brain is associated with...

    Cheryl A. Hawkes, Christopher J. Heath, ... Roxana O. Carare in Acta Neuropathologica Communications
    Article Open access 31 August 2022
  17. EGR3 regulates opioid-related nociception and motivation in male rats

    Chronic pain can be a debilitating condition, leading to profound changes in nearly every aspect of life. However, the reliance on opioids such as...

    Swarup Mitra, Shruthi A. Thomas, ... David M. Dietz in Psychopharmacology
    Article 13 September 2022
  18. Emotion, Motivation, Personality and Their Neurobiological Foundations

    In this chapter we will deal with three basic components of the human psyche: emotions or feelings, motivation and personality. In the spirit of...
    Gerhard Roth, Nicole Strüber in Psychoneuroscience
    Chapter 2023
  19. Metabotropic glutamate group II receptor activation in the ventrolateral dorsal striatum suppresses incentive motivation for cocaine in rats

    Rationale

    After a history of intermittent cocaine intake, rats develop patterns of drug use characteristic of substance use disorder. The dorsal...

    Shaun Yon-Seng Khoo, Anne-Noël Samaha in Psychopharmacology
    Article 15 April 2023
  20. Pharmacological characterisation of the effort for reward task as a measure of motivation for reward in male mice

    Rationale

    Motivational deficits are a common symptom shared across multiple psychiatric and neurodegenerative disorders. Effort-based decision-making...

    Caterina Marangoni, Melissa Tam, ... Megan G. Jackson in Psychopharmacology
    Article Open access 21 July 2023
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