Search
Search Results
-
The movement of mitochondria in breast cancer: internal motility and intercellular transfer of mitochondria
As a major energy source for cells, mitochondria are involved in cell growth and proliferation, as well as migration, cell fate decisions, and many...
-
Socialized mitochondria: mitonuclear crosstalk in stress
Traditionally, mitochondria are considered sites of energy production. However, recent studies have suggested that mitochondria are signaling...
-
Mitochondria as secretory organelles and therapeutic cargos
Mitochondria have been primarily considered intracellular organelles that are responsible for generating energy for cell survival. However,...
-
Assessment of Bioenergetics in BAT Mitochondria
High-resolution respirometry is commonly used to quantify mitochondrial respiratory rates. In the respirometry chamber, a change in oxygen... -
Endothelial Mitochondria-Associated Membranes (MAMs) Isolation by Percoll Step Gradients
Mitochondria-associated membranes (MAMs) are regions where the endoplasmic reticulum (ER) interacts with mitochondria and regulate lipid trafficking,... -
Extracellular release in the quality control of the mammalian mitochondria
Mammalian cells release a wealth of materials to their surroundings. Emerging data suggest these materials can even be mitochondria with perturbed...
-
Focusing on mitochondria in the brain: from biology to therapeutics
Mitochondria have multiple functions such as supplying energy, regulating the redox status, and producing proteins encoded by an independent genome....
-
Mitochondria Modulating Therapeutic Approaches in the Management of Huntington’s Disease
Purpose of ReviewMitochondrial dysfunctions are considered epistatic to cellular malfunctions during advancement of neurodegenerative disorders,...
-
Biodistribution of Intravenously Transplanted Mitochondria Conjugated with Graphene Quantum Dots in Diabetic Rats
Mitochondria transplantation has emerged as a successful therapeutic modality to treat several degenerative diseases. However, the biodistribution of...
-
Mitochondria-Targeted Antioxidants and Cancer
Antioxidant therapy in cancer is gaining momentum after witnessing a striking success of mitochondria-targeted antioxidants in oxidative... -
Interaction between mitochondria and microbiota modulating cellular metabolism in inflammatory bowel disease
Inflammatory bowel disease (IBD) is a prototypic complex disease in the gastrointestinal tract that has been increasing in incidence and prevalence...
-
Calcium signaling from sarcoplasmic reticulum and mitochondria contact sites in acute myocardial infarction
Acute myocardial infarction (AMI) is a serious condition that occurs when part of the heart is subjected to ischemia episodes, following partial or...
-
Proteomic analysis of mitochondria associated membranes in renal ischemic reperfusion injury
BackgroundThe mitochondria and endoplasmic reticulum (ER) communicate via contact sites known as mitochondria associated membranes (MAMs). Many...
-
Respiratory Function of Mitochondria in Patients with Coronary Heart Disease with Implantable Cardioverter-Defibrillator
We studied the respiratory activity of mitochondria in peripheral blood leukocytes from 36 patients with coronary heart disease (CHD) and a history...
-
Purification of functional mouse skeletal muscle mitochondria using percoll density gradient centrifugation
ObjectiveOur goal was to isolate purified mitochondria from mouse skeletal muscle using a Percoll density gradient and to assess bioenergetic...
-
Relevance of the endoplasmic reticulum-mitochondria axis in cancer diagnosis and therapy
Dynamic interactions between organelles are responsible for a variety of intercellular functions, and the endoplasmic reticulum (ER)–mitochondrial...
-
Shrimp miR-965 transfers tumoricidal mitochondria
BackgroundMicro RNA of Marsupenaeus japonicas has been known to promote apoptosis of tumor cells. However, the detailed mechanisms are not well...
-
Mitochondria-associated programmed cell death as a therapeutic target for age-related disease
Mitochondria, ubiquitous double-membrane-bound organelles, regulate energy production, support cellular activities, harbor metabolic pathways, and,...
-
Engineered inhaled nanocatalytic therapy for ischemic cerebrovascular disease by inducing autophagy of abnormal mitochondria
Mitochondrial dysfunction and subsequent accumulation of reactive oxygen species (ROS) are key contributors to the pathology of ischemic...
-
BDNF-TrkB Signaling in Mitochondria: Implications for Neurodegenerative Diseases
Brain-derived neurotrophic factor (BDNF) plays a pivotal role in neuronal development, synaptic plasticity, and overall neuronal health by binding to...