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MicroRNA Qubit
We use Schröedinger’s wave equation to show that it is possible to work with physical transformations from microRNA (miRNA) information. Quantum... -
MicroRNA Quantum Computing
Due to the multiple targets of microRNA (miRNA) and messenger RNA (mRNA) interactions and the complexity of protein/protein interactions, the... -
Matrix Multiplication for MicroRNA Qubit
MicroRNA (miRNA) sequences were converted into miRNA qubits according to Schröedinger’s wave equation. Cohered interactions between two miRNA qubits... -
The MicroRNA 2000 Transformer Quantum Computing and Artificial Intelligence for Health
The second edition includes new findings that were only a theory in the first edition, clarifying what is beginning to be proven true. All chapters...
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Therapeutic Target MicroRNA Identification Based on Circular RNA Expression Signature After Intracerebral Hemorrhage
We investigated circular RNA (circRNA) expression pattern from a rat intracerebral hemorrhage (ICH) model and tested therapeutic strategy....
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MicroRNA-126 (MiR-126): key roles in related diseases
In eukaryotes such as humans, some non-coding single-stranded RNAs (ncRNAs) help to regulate the pre- and post-transcriptional expression of certain...
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In silico prioritisation of microRNA-associated common variants in multiple sclerosis
BackgroundGenome-wide association studies (GWAS) have highlighted over 200 autosomal variants associated with multiple sclerosis (MS). However,...
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MicroRNA Profiling from Tears as a Potential Non-invasive Method for Early Detection of Diabetic Retinopathy
Diabetic retinopathy (DR) is a vascular complication of diabetes that can lead to partial or complete loss of vision. Early detection and treatment... -
Peripheral whole blood microRNA expression in relation to vascular function: a population-based study
BackgroundAs key regulators of gene expression, microRNAs affect many cardiovascular mechanisms and have been associated with several cardiovascular...
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The Search for and Functional Analysis of Genetic Variants in microRNA-Binding Sites using Massively Parallel Reporter Assay
A large-scale search for the genetic variants with a bias in the representation of alleles in transcriptome data (AE SNPs) and the binding sites in...
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The Role of MicroRNA in Migraine: A Systemic Literature Review
Migraine is a common primary headache disorder, affecting about 14% of the population. Importantly, it was indicated as the second cause of...
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The MicroRNA Quantum Code Book
This book tells the story of the discovery of microRNA (miRNA) quantum code, the basic theory of biological data science for medical investigation...
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Validation of microRNA Target Genes Using Luciferase Reporter assay and Western Blot Analysis
MicroRNA MicroRNA (miRNA) s regulate gene expressionGene expression by binding to the 3′untranslated region (UTR) of the mRNA of their target genes.... -
Mobile MicroRNAs: Potential for MicroRNA Biogenesis
As shown in Chap. 2 , the short interfering RNA (siRNA) system was thought to be the same as the microRNA (miRNA)... -
Neuroprotective Therapeutic Potential of microRNA-149-5p against Murine Ischemic Stroke
Ischemic stroke resulting from blockade of brain vessels lacks effective treatments, prompting exploration for potential therapies. Among promising...
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A novel microRNA signature for the detection of melanoma by liquid biopsy
BackgroundMelanoma is the deadliest form of skin cancer and metastatic disease is associated with a significant survival rate drop. There is an...
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Small Noncoding RNA, microRNA in Gene Regulation
A large portion of the human genome is devoted to producing noncoding RNA. A majority of ncRNA are involved in complex regulatory networks that... -
MicroRNA Signatures of Tumor Hypoxia
Micro RNAs (miRNAs) are regulatory RNA molecules that can act as oncogenes or tumor suppressors. Over the years, many studies have documented altered... -
Investigating the role of let-7a microRNA in cisplatin sensitivity of A549 lung cancer cells
Lung cancer (LC) is a major cause of death worldwide, and cisplatin is commonly used as a chemotherapeutic drug for the treatment of LC. However,...