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A multicenter noninferior randomized controlled study of sentinel lymph node biopsy alone versus sentinel lymph node biopsy plus lymphadenectomy for patients with stage I endometrial cancer, INSEC trial concept
BackgroundUp to the present time, there has remained a lack of strong evidence as to whether sentinel lymph node biopsy can replace lymphadenectomy...
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Same yet different — how lymph node heterogeneity affects immune responses
Lymph nodes are secondary lymphoid organs in which immune responses of the adaptive immune system are initiated and regulated. Distributed throughout...
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Correlation between Structural Transformations in Mesenteric Lymph Nodes and the Levels MicroRNA during Polychemotherapy of Breast Cancer
We studied interrelationships between the cytoarchitectonics of the mesenteric lymph node and the levels of microRNA-21, microRNA-221/222, and...
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Neonatal LTβR signaling is required for the accumulation of eosinophils in the inflamed adult mesenteric lymph node
Although eosinophils are important contributors to mucosal immune responses, mechanisms that regulate their accumulation in mucosal-associated...
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Mesenteric Adenopathy and Adenitis
Mesenteric adenopathy and adenitis are common causes of abdominal pain, requiring emergency admission to hospital. The term mesenteric adenitis is...
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Primary tumour immune response and lymph node yields in colon cancer
BackgroundThe mechanism underlying improved survival in non-metastatic colon cancer with higher lymph node (LN) yield is unknown. This study aimed to...
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Influence of Surgical Treatment and Neoadjuvant Therapy of Chemically Induced Breast Cancer on Correlation of Cytokine Concentrations in the Lymph with Structural Transformations in the Mesenteric Lymph Nodes
We performed a correlation analysis of the morphometry of mesenteric lymph nodes and cytokines of the thoracic duct lymph in chemically induced...
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Assessment of retroperitoneal lymph node status in locally advanced cervical cancer
BackgroundThe assessment of retroperitoneal lymph node status in patients with locally advanced cervical cancer is still a problem. This study aimed...
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The microbiota is dispensable for the early stages of peripheral regulatory T cell induction within mesenteric lymph nodes
Intestinal Foxp3 + regulatory T cell (Treg) subsets are crucial players in tolerance to microbiota-derived and food-borne antigens, and compelling...
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Mapping patterns of para-aortic lymph node recurrence in cervical cancer: a retrospective cohort analysis
BackgroundTo map anatomic patterns of para-aortic lymph node (PALN) recurrence in cervical cancer patients and validate currently available...
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T-bet and RORα control lymph node formation by regulating embryonic innate lymphoid cell differentiation
The generation of lymphoid tissues during embryogenesis relies on group 3 innate lymphoid cells (ILC3) displaying lymphoid tissue inducer (LTi)...
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Infection with the enteric pathogen C. rodentium promotes islet-specific autoimmunity by activating a lymphatic route from the gut to pancreatic lymph node
In nonobese diabetic (NOD) mice, C. rodentium promotes priming of islet-specific T-cells in pancreatic lymph nodes (PaLN), which is a critical step...
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Portal blood flow–dependent NO-mediated lymph formation in rat jejunum
The higher permeability of the venules in jejunal microcirculation to albumin contributes to the increased mesenteric lymph formation. Recently, we...
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Topographic distribution of lymph node metastasis in patients with stage IB1 cervical cancer: an analysis of 8314 lymph nodes
BackgroundSystematic pelvic lymphadenectomy or whole pelvic irradiation is recommended for the patients with stage IB1 cervical cancer. However, the...
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Cell surface ATP synthase-released H+ and ATP play key roles in cocoa butter intake-mediated regulation of gut immunity through releases of cytokines in rat
Proper food intake is important for maintaining good health in humans. Chocolate is known to exert anti-inflammatory effects; however, the mechanisms...
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The role of sentinel lymph node mapping in colon cancer: detection of micro-metastasis, effect on survival, and driver of a paradigm shift in extent of colon resection
Unlike in breast cancer and melanoma, sentinel lymph node mapping in colon cancer is primarily used as an aid to the pathologist for accurate nodal...
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Ultrasound-guided fine needle aspiration cytology of Para-aortic lymph node metastasis in uterine cervical cancer: diagnostic accuracy and impact on clinical decision making
ObjectiveThe main aim of this study was to ascertain the effectiveness of ultrasound-guided fine needle aspiration cytology (US-FNAC) in the...
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The lymphatic system and sentinel lymph nodes: conduit for cancer metastasis
The lymphatic system is a complicated system consisting of the lymphatic vessels and lymph nodes draining the extracellular fluid containing cellular...
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Structural and Functional Changes in the Mesenteric Lymph Nodes in Humans during Aging
Morphometric analysis of structural and functional changes in the human mesenteric lymph nodes during aging revealed the development of fibrous...
