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Hypertension care cascades and reducing inequities in cardiovascular disease in low- and middle-income countries
Improving hypertension control in low- and middle-income countries has uncertain implications across socioeconomic groups. In this study, we...
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Overcoming barriers to single-cell RNA sequencing adoption in low- and middle-income countries
The advent of single-cell resolution sequencing and spatial transcriptomics has enabled the delivery of cellular and molecular atlases of tissues and...
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Addressing cancer care in low- to middle-income countries: a call for sustainable innovations and impactful research
Most new cancer cases are currently arising in low- and middle-income countries, where their outcomes are significantly poorer compared to...
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Clinical and Regulatory Challenges and Opportunities for Monoclonal Antibodies in Low- and Middle-Income Countries: Lessons from COVID-19 and Beyond
Monoclonal antibodies are an effective and growing class of pharmaceuticals for the treatment and prevention of a broad range of non-communicable and...
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Economic evaluation of germline genetic testing for breast cancer in low- and middle-income countries: a systematic review
BackgroundBreast cancer (BC) is the most common cancer affecting women globally. Genetic testing serves as a prevention and treatment strategy for...
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Not recommended fixed-dose antibiotic combinations in low- and middle-income countries – the example of Tanzania
BackgroundFixed-dose combinations (FDC) are medicine formulations that combine two or more ingredients in fixed ratios in a single dose form....
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Diagnosis of Childhood Tuberculosis in Low- and Middle-Income Countries
Pediatric tuberculosis (TB) is one of the neglectedDiseaseneglected groups globally. Non-specific symptomsSymptom, the paucibacillary nature of the...
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A practical approach for adoption of a hub and spoke model for cell and gene therapies in low- and middle-income countries: framework and case studies
In the rapidly evolving landscape of biotechnologies, cell and gene therapies are being developed and adopted at an unprecedented pace. However,...
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International cooperation to fight cancer’s late-stage presentation in low- and middle-income countries
Cancer is becoming a massive public health burden in low- and middle-income countries (LMIC). 70% of all cancer deaths globally are attributed to...
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Physician-brief advice for promoting smoking cessation among cancer patients on treatment in low and middle-income countries: a scoping review
IntroductionPhysician-brief advice has been utilized in high-income countries to promote smoking cessation among cancer patients. Empirical evidence...
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Researchers should no longer delay implementation of Pap screening in low and middle income countries pending research into novel screening approaches
A study coordinated by Groesbeck Parham and Mark Schiffman describes a novel approach to single-visit, point-of-care cervical screening and triage...
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Integrated malaria prevention in low- and middle-income countries: a systematic review
BackgroundAs many countries aim to eliminate malaria, use of comprehensive approaches targeting the mosquito vector and environment are needed....
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Priorities for cancer research in low- and middle-income countries: a global perspective
Cancer research currently is heavily skewed toward high-income countries (HICs), with little research conducted in, and relevant to, the problems of...
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Trends in Prescribing Antibiotics Between 2012 and 2022: High-Income Versus Low-Middle-Income Countries
Antimicrobial resistance (AMR) is a major public health threat. This increase in resistance is in line with the high rate of antibiotic consumption,...
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Mental Health Services in Low- and Middle-Income Countries
Mental health services are defined as “the means by which effective interventions for mental health are delivered.” The effectiveness of these...
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Association of severe malaria with cognitive and behavioural outcomes in low- and middle-income countries: a meta-analysis and systematic review
BackgroundMalaria affects 24 million children globally, resulting in nearly 500,000 child deaths annually in low- and middle-income countries...
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Modifiable risk factors for prostate cancer in low- and lower-middle-income countries: a systematic review and meta-analysis
BackgroundMost of the epidemiological data on prostate cancer risk factors come from high-income countries (HIC). Reducing exposure to prostate...
