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Spatiotemporal Patterns of Corticomuscular Interactions in Locomotion
This study addressed the synergistic effects apparent at the cortical and muscular levels during locomotor activity performed under conditions in...
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The mesencephalic locomotor region recruits V2a reticulospinal neurons to drive forward locomotion in larval zebrafish
The mesencephalic locomotor region (MLR) is a brain stem area whose stimulation triggers graded forward locomotion. How MLR neurons recruit...
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Locomotion: Circuits and Physiology
Locomotion is a complex motor behavior needed by animals and humans to move through the environment. All forms of locomotion, including swimming,... -
A Data-Driven Approach to Estimate Human Center of Mass State During Perturbed Locomotion Using Simulated Wearable Sensors
Center of mass (COM) state, specifically in a local reference frame (i.e., relative to center of pressure), is an important variable for controlling...
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D-Ribose-L-Cysteine and L-Dopa Co-Supplementation Attenuates Paraquat-Induced Oxidative Damage and Locomotion Deficit in Drosophila melanogaster
AbstractD-ribose L-cysteine is a glutathione precursor that acts as an antioxidant. In the present study, we investigated the effect of D-ribose...
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Neural Endophenotype Assessment in Zebrafish Larvae Using Optomotor and ZebraBox Locomotion Assessment
Due to the highly conserved genetics across the central nervous system, the easily probed visual system can act as an endophenotype for assessing... -
Capitalizing on skin in orthotics design: the effects of texture on plantar intrinsic foot muscles during locomotion
Foot orthoses (FO) are a commonly prescribed intervention to alter foot function during walking although their effects have been primarily studied in...
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A Simple Method for Quantifying Larval Locomotion in Drosophila melanogaster
The fruit fly Drosophila melanogaster is a powerful genetic model that has been used for many decades to study nervous system function, development,... -
The effect of texture under distinct regions of the foot sole on human locomotion
Sensory feedback from the foot sole plays an important role in shaping human locomotion. While net muscle activity and kinematic changes have been...
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Eye Tracking Application to Understand the Visual Control of Locomotion
Visual information is crucial for safe locomotion because it allows individuals to adjust their stepping patterns to deal with environmental demands.... -
Vaporized nicotine in utero results in reduced birthweight, increased locomotion, and decreased voluntary exercise, dependent on sex and diet in offspring
Rationale Clinical research has shown that prenatal exposure to nicotine may result in increased obesity risk later in life. Preclinical research has...
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Network pharmacology and molecular docking–based investigation of monocyte locomotion inhibitory factor attenuates traumatic brain injury by regulating aquaporin 4 expression
Traumatic brain injury (TBI) is a significant cause of disability and mortality worldwide, and effective treatment options are currently limited....
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Quantification of Parkinsonian Kinematic Patterns in Body-Segment Regions During Locomotion
PurposeDiagnosis and treatment of Parkinson’s Disease (PD) are typically supported by a kinematic gait analysis. Nonetheless, the main drawbacks of...
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Different generalization of fast and slow visuomotor adaptation across locomotion and pointing tasks
Sensorimotor adaptation can involve multiple learning processes with different time courses, and these processes may have different patterns of...
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Deep reinforcement learning for modeling human locomotion control in neuromechanical simulation
Modeling human motor control and predicting how humans will move in novel environments is a grand scientific challenge. Researchers in the fields of...
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Homing tasks and distance matching tasks reveal different types of perceptual variables associated with perceiving self-motion during over-ground locomotion
Self-motion perception refers to the ability to perceive how the body is moving through the environment. Perception of self-motion has been shown to...
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The Putative Drosophila TMEM184B Ortholog Tmep Ensures Proper Locomotion by Restraining Ectopic Firing at the Neuromuscular Junction
TMEM184B is a putative seven-pass membrane protein that promotes axon degeneration after injury. TMEM184B mutation causes aberrant neuromuscular...
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Rrn3 gene knockout affects ethanol-induced locomotion in adult heterozygous zebrafish
Genome-wide analysis has identified the transcription factor, RRN3 (or TIF-1A ), on human chromosome 16p13.11 as a candidate gene associated with...
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Protective Role of Lactobacillus rhamnosus Probiotic in Reversing Cocaine-Induced Oxidative Stress, Glial Activation and Locomotion in Mice
Cocaine abuse is known to cause inflammation, oxidative injury and alterations in the gut microbiota. Although emerging studies have demonstrated the...