Search
Search Results
-
Identification and validation of iron metabolism genes in osteoporosis
BackgroundOsteoporosis is the most common metabolic bone disease in humans. Exploring the expression difference of iron metabolism-related genes in...
-
Contrasting Iron Metabolism in Undifferentiated Versus Differentiated MO3.13 Oligodendrocytes via IL-1β-Induced Iron Regulatory Protein 1
Parkinson’s disease (PD) is a prevalent neurodegenerative disorder characterized by the loss of dopaminergic neurons and the accumulation of iron in...
-
Iron metabolism: backfire of cancer cell stemness and therapeutic modalities
Cancer stem cells (CSCs), with their ability of self-renewal, unlimited proliferation, and multi-directional differentiation, contribute to...
-
Iron Metabolism and Ferroptosis in Early Brain Injury after Subarachnoid Haemorrhage
At present, it appears that the prognosis for subarachnoid haemorrhage (SAH), which has a high death and disability rate, cannot be greatly improved...
-
The Role of Iron Metabolism in Sepsis-associated Encephalopathy: a Potential Target
Sepsis-associated encephalopathy (SAE) is an acute cerebral dysfunction secondary to infection, and the severity can range from mild delirium to deep...
-
Identification of Immune Infiltration and Iron Metabolism–Related Subgroups in Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a prevalent neurodevelopmental disorder with a broad spectrum of symptoms and prognoses. Effective therapy requires...
-
Brain-Iron Cross Talk
This book explores the molecular mechanisms of iron hemostasis in the brain and discusses the cognitive and behavioral implications of iron...
-
Iron metabolism in colorectal cancer: a balancing act
BackgroundColorectal cancer (CRC) is the third most commonly diagnosed cancer and the second deadliest malignancy worldwide. Current dietary habits...
-
Iron metabolism, ferroptosis, and lncRNA in cancer: knowns and unknowns
Cancer cells undergo substantial metabolic alterations to sustain increased energy supply and uncontrolled proliferation. As an essential trace...
-
The Role of Iron Metabolism, Lipid Metabolism, and Redox Homeostasis in Alzheimer’s Disease: from the Perspective of Ferroptosis
In the development of Alzheimer’s disease (AD), cell death is common. Novel cell death form—ferroptosis is discovered in recent years. Ferroptosis is...
-
The role of iron metabolism in chronic diseases related to obesity
Obesity is one of the major public health problems threatening the world, as well as a potential risk factor for chronic metabolic diseases. There is...
-
Iron in Shaping Cancer Biology
Iron is a key micronutrient with a multifaceted role in cell biology, as it is essential for cell survival, cell proliferation, DNA repair, and ATP...
-
Altered iron metabolism as a target for ferroptosis induction in head and neck cancer
Iron is a mineral micronutrient essential for survival and vital functions in many biological processes in living organisms. Iron plays a crucial...
-
Therapy-resistant nature of cancer stem cells in view of iron metabolism
Due to increased resistance to standard chemo/radiotherapies and relapse, highly tumorigenic cancer stem cells (CSCs) have been proposed as a...
-
Construction of iron metabolism-related prognostic features of gastric cancer based on RNA sequencing and TCGA database
BackgroundResearches have manifested that the disorder of iron metabolism is participated in Gastric cancer (GC), but whether iron...
-
Gemfibrozil Alleviates Cognitive Impairment by Inhibiting Ferroptosis of Astrocytes via Restoring the Iron Metabolism and Promoting Antioxidant Capacity in Type 2 Diabetes
Diabetes-associated cognitive dysfunction (DACD) is considered a significant complication of diabetes and manifests as cognitive impairment....
-
Iron and Neuropathies
Iron is an indispensable element for metabolic reactions as it is involved in protein synthesis, brain functions, nerve conduction, and myelination....
-
Genome-wide analysis of a model-derived binge eating disorder phenotype identifies risk loci and implicates iron metabolism
Binge eating disorder (BED) is the most common eating disorder, yet its genetic architecture remains largely unknown. Studying BED is challenging...
-
Iron and Epilepsy
Epilepsy is a disorder defined by repeated, recurrent, and temporary impairment of the brain (CNS) caused by an abnormally rhythmic discharge of...
-
Iron and Multiple Sclerosis
Multiple sclerosis (MS) is a chronic autoimmune neurodegenerative disease followed by demyelination and axonal loss. There had been several reports...
