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Immune Regulation
Immune regulation is the regulation and control of the immune response by the immune system in order to maintain homeostasis of the organism. Once...
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Dissecting the Immune System through Gene Regulation
The immune system plays a dual role in human health, functioning both as a protector against pathogens and, at times, as a contributor to disease....
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Transcriptional Signatures of a Dynamic Epilepsy Process Reveal Potential Immune Regulation
Epilepsy is a progression of development and advancement over time. However, the molecular features of epilepsy were poorly studied from a dynamic...
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Immune regulation through tryptophan metabolism
Amino acids are fundamental units of molecular components that are essential for sustaining life; however, their metabolism is closely interconnected...
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Immune Homeostasis Methods and Protocols
This volume discusses different aspects of immune homeostasis regulation and its dysregulation during various diseases, including infections,...
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Central regulation of stress-evoked peripheral immune responses
Stress-linked psychiatric disorders, including anxiety and major depressive disorder, are associated with systemic inflammation. Recent studies have...
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Unconventional immune cells in the gut mucosal barrier: regulation by symbiotic microbiota
The mammalian gut is the most densely colonized organ by microbial species, which are in constant contact with the host throughout life. Hosts have...
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Phase separation in immune regulation and immune-related diseases
Phase separation is an emerging paradigm for understanding the biochemical interactions between proteins, DNA, and RNA. Research over the past decade...
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Exploring CCR5 + T regulatory cell subset dysfunction in type 1 diabetes patients: implications for immune regulation
T regulatory lymphocytes (Treg) expressing CCR5 exhibit strong suppression activity in various autoimmune disorders. However, there remains a lack of...
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Microbiota Metabolites and Immune Regulation Affect Ischemic Stroke Occurrence, Development, and Prognosis
The gut microbiota are not only related to the development and occurrence of digestive system disease, but also have a bidirectional relationship...
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Redox regulation of the immune response
The immune-inflammatory response is associated with increased nitro-oxidative stress. The aim of this mechanistic review is to examine: (a) the role...
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PD-1/PD-L1 axis: implications in immune regulation, cancer progression, and translational applications
The PD-1/PD-L1 axis is a complex signaling pathway that has an important role in the immune system cells. Programmed cell death protein 1 (PD-1) acts...
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AP4M1 as a prognostic biomarker associated with cell proliferation, migration and immune regulation in hepatocellular carcinoma
BackgroundAP4M1 is a protein-coding gene that plays a crucial role in transporter activity, recognition, and hereditary-associated diseases, but...
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Microbiota-dependent regulation of costimulatory and coinhibitory pathways via innate immune sensors and implications for immunotherapy
Our bodies are inhabited by trillions of microorganisms. The host immune system constantly interacts with the microbiota in barrier organs, including...
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Immune regulation and prognosis indicating ability of a newly constructed multi-genes containing signature in clear cell renal cell carcinoma
BackgroundClear cell renal cell carcinoma (ccRCC) is the most common renal malignancy, although newly developing targeted therapy and immunotherapy...
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Modeling and Remodeling the Cell: How Digital Twins and HCMV Can Elucidate the Complex Interactions of Viral Latency, Epigenetic Regulation, and Immune Responses
Purpose of ReviewHuman cytomegalovirus (HCMV), while asymptomatic in most, causes significant complications during fetal development, following...
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The Immune System
The mammalian immune system is a defensive system of the body that has evolved over time and includes immune organs, immune cells, and immune...
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Noninvasive ultrasound stimulation to treat myocarditis through splenic neuro-immune regulation
BackgroundThe cholinergic anti-inflammatory pathway (CAP) has been widely studied to modulate the immune response. Current stimulating strategies are...
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RNA Metabolism Governs Immune Function and Response
Inflammation is a complex process that protects our body from various insults such as infection, injury, and stress. Proper inflammation is...
