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Effect of a short video on patients’ motivation for dose reduction or cessation of hypnotics
Recently, addiction to regular doses of hypnotics has become a problem. While many patients report a desire to reduce their dosage, many do not agree...
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Management of chronic insomnia using hypnotics: a friend or a foe?
Epidemiological studies suggest that 10–15% adults meet the present criteria for the diagnosis of insomnia disorder; however, there may be...
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Screening Methods for the Evaluation of Sedative-Hypnotics
Sedatives cause calmness, drowsiness, and reduced motor coordination, while hypnotics induce/maintain sleep. Due to the discovery of various classes...
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Hypnotics and Sedatives
Sleep is an active physiological process which harmonizes the brain function. A sedative is a drug which reduces activity and alertness by producing...
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The Use of Hypnotics for Insomnia Disorder in Saudi Arabia: A Survey of Patients’ Experiences and Perceptions
PurposeThis study investigated the experiences and perceptions of Saudi patients with insomnia disorder.
MethodA cross-sectional design study (July...
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Roles of sedative-hypnotics in patients with recurrent major depressive disorder: a nationwide population-based 14-year follow-up study in Taiwan
BackgroundThe use of sedatives or hypnotics and the recurrence of depression have not been adequately explored. This study investigated the roles of...
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Impact of zolpidem and lemborexant on sleep and morning symptoms when used as a single dose for polysomnography
This study evaluated the effect of zolpidem and lemborexant on sleep and morning symptoms in patients undergoing type-1 polysomnography for suspected...
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Elevated perceived stress scale (PSS) scores are associated with increased risk of poor sleep assessed by global PSQI scores: cancer and hypnotics-stratified analysis in an adult population-based study
Patients with cancer tend to have an increased risk of sleep disorders. The exact association between cancer and sleep disorders remains uncertain....
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Efficacy of combined use of Suvorexant and Ramelteon in preventing postoperative delirium: a retrospective comparative study
BackgroundSuvorexant and ramelteon have been presented as useful for preventing postoperative delirium. Previous studies reported on the comparison...
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Benzodiazepines, z-Hypnotics, and Risk of Dementia: Special Considerations of Half-Lives and Concomitant Use
The utilization of benzodiazepines (BZDs) and z-hypnotics has substantially increased with the aging of the population, but the risk of BZDs and...
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Complaints of daytime sleepiness, insomnia, hypnotic use, and risk of dementia: a prospective cohort study in the elderly
BackgroundSleep disturbances are common in elderly and occur frequently in dementia. The impact of excessive daytime sleepiness (EDS), insomnia...
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Psychometric properties of the Youth Self-rated Insomnia Scale (YSIS) in adolescent psychiatric patients
The 8-item Youth Self-rated Insomnia Scale (YSIS) was developed to assess insomnia severity in the past month among youths. The YSIS has satisfactory...
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Use of psychotropic medication and risk of road traffic crashes: a registry-based case–control study in Denmark, 1996–2018
RationaleUse of psychotropics is relatively prevalent amongst motor vehicle drivers because mobility is also important for persons suffering from...
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Sleep During Hypnotic Therapy
Insomnia is a significant public health burden with a prevalence rate of 5–50% in the general population. Evidence indicates that histaminergic,...
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Prevalence trends and individual patterns of ADHD medication use in pregnancy in Norway and Sweden, 2010–2019
PurposeThis study aimed to describe recent trends in ADHD medication use in pregnancy in Norway and Sweden, including prevalence, individual...
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Insomnia-related rodent models in drug discovery
Despite the widespread prevalence and important medical impact of insomnia, effective agents with few side effects are lacking in clinics. This is...
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The abuse potential of lemborexant, a dual orexin receptor antagonist, according to the 8 factors of the Controlled Substances Act
RationaleLemborexant (LEM) is a dual orexin receptor antagonist (DORA) approved in multiple countries including the USA, Japan, Canada, Australia,...
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Management of Chronic Insomnia Using Cognitive Behavior Therapy for Insomnia (CBT-I) During COVID-19 Pandemic: Does One Shoe Fit All?
PurposeInsomnia is a highly prevalent disorder that is seen across all age groups causing significant morbidity to the patients. Its prevalence has...
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Pharmacological Management of Insomnia
Insomnia is a highly prevalent condition associated with significant morbidity, reduction in quality of life, and increase in healthcare costs, and...
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Residual effects of zopiclone on driving performance using a standardized driving simulator among healthy volunteers
RationaleThe effects of hypnotics on automobile driving have been attracting increasing attention. However, few driving simulators (DSs) have been...
