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Computational Neuroscience: Hippocampus
Extensive computational neuroscience research has addressed the functional role of the hippocampus and associated cortical structures. In this field,...
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Reconstruction of the Hippocampus
The hippocampus is a widely studied brain region thought to play an important role in higher cognitive functions such as learning, memory, and...
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Unlocking the Memory Vault: Dopamine, Novelty, and Memory Consolidation in the Hippocampus
Most everyday memories, including numerous episodic memories formed automatically in the hippocampus, are forgotten. However, some memories are...
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Immunohistochemical field parcellation of the human hippocampus along its antero-posterior axis
The primate hippocampus includes the dentate gyrus, cornu ammonis (CA), and subiculum. CA is subdivided into four fields (CA1-CA3, plus CA3h/hilus of...
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The functional and structural changes in the hippocampus of COVID-19 patients
Since the hippocampus is predominantly susceptible to injuries caused by COVID-19, there are increasing data indicating the likelihood of...
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Propensity score-matched analysis comparing hippocampus-avoidance whole-brain radiotherapy plus simultaneous integrated boost with hippocampus‑avoidance whole-brain radiotherapy alone for multiple brain metastases-a retrospective study in multiple institutions
BackgroundThe optimal treatment for multiple brain metastases has been recently controversially discussed.This study was aimed to explore the...
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Disfunction of dorsal raphe nucleus-hippocampus serotonergic-HTR3 transmission results in anxiety phenotype of Neuroplastin 65-deficient mice
Anxiety disorders are the most common psychiatric condition, but the etiology of anxiety disorders remains largely unclear. Our previous studies have...
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Keratinocyte-Derived Cytokine in the Hippocampus Disrupts Extinction of Conditioned Fear Memory in Tumor-Bearing Mice
While patients with cancer show a higher prevalence of psychiatric disorders than the general population, the mechanism underlying this interaction...
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Altered DTI scalars in the hippocampus are associated with morphological and structural changes after traumatic brain injury
Blunt and diffuse injury is a highly prevalent form of traumatic brain injury (TBI) which can result in microstructural alterations in the brain. The...
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Clinical Correlation of Altered Molecular Signatures in Epileptic Human Hippocampus and Amygdala
Widespread alterations in the expression of various genes could contribute to the pathogenesis of epilepsy. The expression levels of various genes,...
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A Single-Cell Transcriptomic Analysis of the Mouse Hippocampus After Voluntary Exercise
Exercise has been recognized as a beneficial factor for cognitive health, particularly in relation to the hippocampus, a vital brain region...
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Deep convolutional neural network for hippocampus segmentation with boundary region refinement
Accurately segmenting the hippocampus from magnetic resonance (MR) brain images is a crucial step in studying brain disorders. However, this task is...
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Non-invasive temporal interference electrical stimulation of the human hippocampus
Deep brain stimulation (DBS) via implanted electrodes is used worldwide to treat patients with severe neurological and psychiatric disorders....
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Photothrombotic Model to Create an Infarct in the Hippocampus
Photothrombosis is one of the techniques available to reproduce ischemic injuries in animal models. Most of the studies that use photothrombosis...
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Measuring out-of-field dose to the hippocampus in common radiotherapy indications
BackgroundThe high susceptibility of the hippocampus region to radiation injury is likely the causal factor of neurocognitive dysfunctions after...
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Hippocampus: Molecular, Cellular, and Circuit Features in Anxiety
Anxiety disorders are currently a major psychiatric and social problem, the mechanisms of which have been only partially elucidated. The hippocampus...
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Transcriptome Analysis and Epigenetics Regulation in the Hippocampus and the Prefrontal Cortex of VPA-Induced Rat Model
Autism spectrum disorders (ASD) are a highly heterogeneous group of neurodevelopmental disorders caused by complex interaction between various genes...
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Neural Correlates of Spatial Navigation in Primate Hippocampus
The hippocampus has been extensively implicated in spatial navigation in rodents and more recently in bats. Numerous studies have revealed that...
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Smad7 in the hippocampus contributes to memory impairment in aged mice after anesthesia and surgery
BackgroundPostoperative cognitive dysfunction (POCD) is a common neurological complication following anesthesia and surgery. Increasing evidence has...
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Induced expression of rabies glycoprotein in the dorsal hippocampus enhances hippocampal dependent memory in a rat model of Alzheimer’s disease
The Rabies virus is a neurotropic virus that manipulates the natural cell death processes of its host to ensure its own survival and replication....
