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  1. Selective vulnerability of hippocampal sub-regions in patients with subcortical vascular mild cognitive impairment

    Early diagnosis of subcortical vascular mild cognitive impairment (svMCI) is clinically essential because it is the most reversible subtype of all...

    Jianxiang Chen, Jianjun Wang, ... Hanqing Lyu in Brain Imaging and Behavior
    Article Open access 20 April 2024
  2. Effects of childhood maltreatment and major depressive disorder on functional connectivity in hippocampal subregions

    Major Depressive Disorder (MDD) with childhood maltreatment is a prevalent clinical phenotype. Prior studies have observed abnormal hippocampal...

    Huiqin Nie, Tong Yu, ... Hongjun Peng in Brain Imaging and Behavior
    Article 07 February 2024
  3. Predictors of hippocampal tauopathy in people with and at risk for human immunodeficiency virus infection

    Combination antiretroviral therapy (cART) has extended lifespans of people living with HIV (PWH), increasing both the risk for age-related...

    Sophie Nader, Esma Karlovich, ... Susan Morgello in Journal of NeuroVirology
    Article 05 November 2023
  4. Changes in microstructural similarity of hippocampal subfield circuits in pathological cognitive aging

    The hippocampal networks support multiple cognitive functions and may have biological roles and functions in pathological cognitive aging (PCA) and...

    Min Fang, Huanghuang Huang, ... Chu-Chung Huang in Brain Structure and Function
    Article 26 December 2023
  5. Hippocampal Malrotation: Is It Epileptogenic?

    Hippocampal malrotation (HIMAL) is an anatomical phenomenon appearing as incomplete rotation of the hippocampus in the course of ontogenesis. The...

    P. Gencpinar, K. Karaali, ... Ö. Duman in Neurophysiology
    Article 12 April 2024
  6. mTORC1-mediated acquisition of reward-related representations by hippocampal somatostatin interneurons

    Plasticity of principal cells and inhibitory interneurons underlies hippocampal memory. Bidirectional modulation of somatostatin cell mTORC1...

    François-Xavier Michon, Isabel Laplante, ... Jean-Claude Lacaille in Molecular Brain
    Article Open access 03 July 2023
  7. Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes

    The hippocampus is critical for memory and cognition and neuropsychiatric disorders, and its subfields differ in architecture and function....

    Nana Liu, Longjiang Zhang, ... Yue Wu in Nature Genetics
    Article 19 June 2023
  8. Prediction of hippocampal electric field in time series induced by TI-DMS with temporal convolutional network

    Temporal interference deep-brain magnetic stimulation (TI-DMS) induces rhythmic electric field (EF) in the hippocampus to normalize cognitive...

    Xiangyang Xu, Bin Deng, ... Guosheng Yi in Cognitive Neurodynamics
    Article 11 February 2024
  9. Functional connectivity changes of the hippocampal subregions in anti-N-methyl-D-aspartate receptor encephalitis

    The hippocampus plays an important role in the pathophysiological mechanism of Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis....

    Yujie Yang, Shishun Fu, ... Xiaofen Ma in Brain Imaging and Behavior
    Article 16 February 2024
  10. Myosin Va-dependent Transport of NMDA Receptors in Hippocampal Neurons

    N-methyl-D-aspartate receptor (NMDAR) trafficking is a key process in the regulation of synaptic efficacy and brain function. However, the molecular...

    Ru Gong, Linwei Qin, ... Wei Lu in Neuroscience Bulletin
    Article Open access 30 January 2024
  11. The fasciola cinereum of the hippocampal tail as an interventional target in epilepsy

    Targeted tissue ablation involving the anterior hippocampus is the standard of care for patients with drug-resistant mesial temporal lobe epilepsy....

    Ryan M. Jamiolkowski, Quynh-Anh Nguyen, ... Ivan Soltesz in Nature Medicine
    Article Open access 17 April 2024
  12. Transient global amnesia and hippocampal diffusion restriction: an overlooked radiological finding

    Transient global amnesia (TGA) is characterized by isolated sudden anterograde amnesia. Diffusion restriction can be observed in the hippocampus on...

    Ilkin Iyigundogdu, Zeynep Kaya, ... Eda Derle in Acta Neurologica Belgica
    Article 06 March 2024
  13. Higher-order interactions between hippocampal CA1 neurons are disrupted in amnestic mice

    Across systems, higher-order interactions between components govern emergent dynamics. Here we tested whether contextual threat memory retrieval in...

    Chen Yan, Valentina Mercaldo, ... Sheena A. Josselyn in Nature Neuroscience
    Article 19 July 2024
  14. Hippocampal representations of foraging trajectories depend upon spatial context

    Animals learn trajectories to rewards in both spatial, navigational contexts and relational, non-navigational contexts. Synchronous reactivation of...

    Wan-Chen Jiang, Shengjin Xu, Joshua T. Dudman in Nature Neuroscience
    Article Open access 29 November 2022
  15. Lactoferrin Has a Protective Effect on Mouse Brain Cells after Acute Gamma Irradiation of the Head

    We studied the effect of human lactoferrin on cells of the hippocampal dentate gyrus of 2-2.5-month-old male C57BL/6 mice after acute gamma...

    M. Yu. Kopaeva, A. B. Cherepov, I. Yu. Zaraiskaya in Bulletin of Experimental Biology and Medicine
    Article 01 December 2023
  16. Meta-Analysis of Hippocampal Volume and Episodic Memory in Preterm and Term Born Individuals

    Preterm birth (< 37 weeks gestation) has been associated with memory deficits, which has prompted investigation of possible alterations in...

    Dana M. McCall, Roya Homayouni, ... Noa Ofen in Neuropsychology Review
    Article 15 April 2023
  17. Glucocorticoid Receptor Down-Regulation Affects Neural Stem Cell Proliferation and Hippocampal Neurogenesis

    Dysregulation of the hypothalamic–pituitary–adrenal axis and abnormalities in the glucocorticoid receptor (GR) have been linked to major depressive...

    Seoyeong Kim, Seonguk Yang, ... Jaewon Lee in Molecular Neurobiology
    Article 18 November 2023
  18. Study of the human hippocampal formation: a method for histological and magnetic resonance correlation in perinatal cases

    Little information is available on the magnetic resonance imaging (MRI) determination of the hippocampal formation (HF) during the perinatal period....

    Joaquín González Fuentes, Sandra Cebada-Sánchez, ... Pilar Marcos in Brain Imaging and Behavior
    Article Open access 06 April 2023
  19. Analysis of Surface Expression of NMDAR Subunits in Primary Hippocampal Neurons

    The expression and activity of ionotropic glutamate receptors control signal transduction at the excitatory synapses in the CNS. The NMDAR comprises...
    Viktor Kuchtiak, Tereza Smejkalova, ... Ales Balik in NMDA Receptors
    Protocol 2024
  20. Social navigation modulates the anterior and posterior hippocampal circuits in the resting brain

    Social navigation is a dynamic and complex process that requires the collaboration of multiple brain regions. However, the neural networks for...

    Xiaoyan Wu, Lu Zhang, ... Ruiwang Huang in Brain Structure and Function
    Article 23 February 2023
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