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Global Tuberculosis Epidemiology
Tuberculosis (TB), despite being curable and preventable, remained on the list of top ten mortalityMortality causes across the globe. TB-HIVTB-HIV...
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Genomics for monitoring and understanding species responses to global climate change
All life forms across the globe are experiencing drastic changes in environmental conditions as a result of global climate change. These...
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Pedunculopontine Chx10+ neurons control global motor arrest in mice
Arrest of ongoing movements is an integral part of executing motor programs. Behavioral arrest may happen upon termination of a variety of...
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Causes and costs of global COVID-19 vaccine inequity
Despite the rapid development of safe and effective COVID-19 vaccines and the widely recognized health and economic benefits of vaccination, there...
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Global burden of MDR-TB and XDR-TB attributable to high fasting plasma glucose from 1990 to 2019: a retrospective analysis based on the global burden of disease study 2019
PurposeHigh fasting plasma glucose (HFPG) has been identified as a risk factor for drug-resistant tuberculosis incidence and mortality. However, the...
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LGDNet: local feature coupling global representations network for pulmonary nodules detection
AbstractDetection of suspicious pulmonary nodules from lung CT scans is a crucial task in computer-aided diagnosis (CAD) systems. In recent years,...
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Global Functional Connectivity is Associated with Mind Wandering Domain of Comfort
The resting-state paradigm is frequently applied to study spontaneous activity of the brain in normal and clinical conditions. To assess the...
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Seedling root system adaptation to water availability during maize domestication and global expansion
The maize root system has been reshaped by indirect selection during global adaptation to new agricultural environments. In this study, we...
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The global burden of cervical cancer requiring surgery: database estimates
BackgroundScaling up surgical services for cervical cancer in low and middle income countries requires quantification of the need for those services....
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Genome-wide ATAC-see screening identifies TFDP1 as a modulator of global chromatin accessibility
Chromatin accessibility is a hallmark of active regulatory regions and is functionally linked to transcriptional networks and cell identity. However,...
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Global diversity and biogeography of DNA viral communities in activated sludge systems
BackgroundActivated sludge (AS) systems in wastewater treatment plants (WWTPs) harbor enormous viruses that regulate microbial metabolism and...
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Involvement of Proteasomal and Endoplasmic Reticulum Stress in Neurodegeneration After Global Brain Ischemia
A brief period of transient global brain ischemia leads to selective ischemic neurodegeneration associated with death of hippocampal CA1 pyramidal...
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Artificial Intelligence for Global Healthcare
The recent world economic challenging status and widened poor-rich gap have established additional risk for the global population, particularly in...
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Closing the antimicrobial stewardship gap - a call for LMICs to embrace the global antimicrobial stewardship accreditation scheme
The escalating challenge of antimicrobial resistance (AMR) poses a considerable concern for global health, particularly impacting low- and...
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Principles and methods for transferring polygenic risk scores across global populations
Polygenic risk scores (PRSs) summarize the genetic predisposition of a complex human trait or disease and may become a valuable tool for advancing...
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The global distribution and environmental drivers of the soil antibiotic resistome
BackgroundLittle is known about the global distribution and environmental drivers of key microbial functional traits such as antibiotic resistance...
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Optimal global spending for group A Streptococcus vaccine research and development
Group A Streptococcus (Strep A) leads to 600,000 deaths and 600 million cases of pharyngitis annually. Although long a promising target for vaccine...
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A simulation-based comparative effectiveness analysis of policies to improve global maternal health outcomes
The Sustainable Development Goals include a target to reduce the global maternal mortality ratio (MMR) to less than 70 maternal deaths per 100,000...
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Elucidating causative gene variants in hereditary Parkinson’s disease in the Global Parkinson’s Genetics Program (GP2)
The Monogenic Network of the Global Parkinson’s Genetics Program (GP2) aims to create an efficient infrastructure to accelerate the identification of...
