Search
Search Results
-
Cerebellar Developmental Disorders and Cerebellar Nuclei
While significant progress has been made in the last 10 years in understanding the development of cerebellar nuclei, they remain a relatively less...
-
Developmental Disorders of the Cerebellum and Neurotrophic Factors
The cerebellum plays a central role in motor control and cognition features such as attention. Thus, a disturbance in cerebellar development results...
-
Nuclear speckleopathies: developmental disorders caused by variants in genes encoding nuclear speckle proteins
Nuclear speckles are small, membrane-less organelles that reside within the nucleus. Nuclear speckles serve as a regulatory hub coordinating complex...
-
Development and Developmental Disorders of the Forebrain
The forebrain comprises those structures that are derived from the most rostral part of the neural plate, i.e. the primary prosencephalon. The...
-
Development and Developmental Disorders of the Cerebral Cortex
The cerebral cortex can be divided into a large isocortex, a much smaller allocortex (the hippocampal formation and the olfactory cortex), and a...
-
Development and Developmental Disorders of the Human Cerebellum
The cerebellum is one of the best studied parts of the brain. The cerebellar cortex is composed of four main types of neurons: granule cells,...
-
Development and Developmental Disorders of the Spinal Cord
Even after its development is complete, the spinal cord remains a rather simple structure with a ventral motor horn, a dorsal sensory horn and an...
-
Development and Developmental Disorders of the Brain Stem
The brain stem is composed of the midbrain (the mesencephalon) and the hindbrain (the rhombencephalon), and is, at least during development,...
-
The developmental timing of spinal touch processing alterations predicts behavioral changes in genetic mouse models of autism spectrum disorders
Altered somatosensory reactivity is frequently observed among individuals with autism spectrum disorders (ASDs). Here, we report that although...
-
Clinical Features, Assessment, and Management of Patients with Developmental and Other Cerebellar Disorders
The cerebellum is essential for processing, modulating, and controlling movement, behavior, social, and cognitive functions. Cerebellar disorders...
-
Molecular mechanisms of environmental pollutant-induced cartilage damage: from developmental disorders to osteoarthritis
The objective of the present study was to review the molecular mechanisms of the adverse effects of environmental pollutants on chondrocytes and...
-
Genetic Aspects of Speech Disorders in Children
Speech disorders remain one of the main challenges in pediatric neurology. The development of genetic diagnostics is producing ever more data on the...
-
Genetic modifiers of rare variants in monogenic developmental disorder loci
Rare damaging variants in a large number of genes are known to cause monogenic developmental disorders (DDs) and have also been shown to cause milder...
-
Genetic determinants of global developmental delay and intellectual disability in Ukrainian children
BackgroundGlobal developmental delay or intellectual disability usually accompanies various genetic disorders as a part of the syndrome, which may...
-
High diagnostic potential of short and long read genome sequencing with transcriptome analysis in exome-negative developmental disorders
Exome sequencing (ES) has become the method of choice for diagnosing rare diseases, while the availability of short-read genome sequencing (SR-GS) in...
-
CNV profiles of Chinese pediatric patients with developmental disorders
PurposeTo examine the overall genomic copy-number variant (CNV) landscape of Chinese pediatric patients with developmental disorders.
...
-
Developmental Impairments of Synaptic Refinement in the Thalamus of a Mouse Model of Fragile X Syndrome
AbstractWhile somatosensory over-reactivity is a common feature of autism spectrum disorders such as fragile X syndrome (FXS), the thalamic...
-
Interrelation Between the Immune and the Nervous Systems in the Context of Cerebellar Development and Developmental Disorders
In recent years, the interplay between the development and function of the central nervous system and the immune system in the homeostatic and...
-
The exocyst complex in neurological disorders
Exocytosis is the process by which secretory vesicles fuse with the plasma membrane to deliver materials to the cell surface or to release cargoes to...
-
Anxiety Disorders
The chapter highlights “anxiety” as a continuum from a normal psychological and functional phenomenon to a pathological state, which in the form of...
