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Palliative Care and Dementia
Palliative care is an important and relevant approach for people with dementia. Integrating its principles in the care for them and their family... -
Plasma metabolic profiles predict future dementia and dementia subtypes: a prospective analysis of 274,160 participants
BackgroundBlood-based biomarkers for dementia are gaining attention due to their non-invasive nature and feasibility in regular healthcare settings....
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Brain Banking in Dementia Studies
It is now well-established practice in dementia that one clinical entity may be caused by various neurodegenerative disorders, each with different... -
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Addition of inflammation-related biomarkers to the CAIDE model for risk prediction of all-cause dementia, Alzheimer’s disease and vascular dementia in a prospective study
BackgroundIt is of interest whether inflammatory biomarkers can improve dementia prediction models, such as the widely used Cardiovascular Risk...
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AI-based differential diagnosis of dementia etiologies on multimodal data
Differential diagnosis of dementia remains a challenge in neurology due to symptom overlap across etiologies, yet it is crucial for formulating...
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Gut microbiota, circulating cytokines and dementia: a Mendelian randomization study
BackgroundSome studies have shown that gut microbiota may be associated with dementia. However, the causal effects between gut microbiota and...
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The Bilateral Carotid Artery Stenosis (BCAS) Model of Vascular Dementia
Vascular dementia is the second most common form of dementia after Alzheimer’s disease. Chronic cerebral hypoperfusion is a key contributor to the... -
High cognitive reserve attenuates the risk of dementia associated with cardiometabolic diseases
BackgroundCardiometabolic diseases (CMDs) including type 2 diabetes, heart disease, and stroke have been linked to a higher risk of dementia. We...
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Genetic evidence for causal association between migraine and dementia: a mendelian randomization study
BackgroundThere is an association between migraine and dementia, however, their causal relationship remains unclear. This study employed...
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Equine-assisted services for people living with dementia: a systematic review
BackgroundDementia has a significant impact on the social, physical, and psychological wellbeing of people living with dementia, their families and...
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Causal relationship between dietary salt intake and dementia risk: Mendelian randomization study
ObjectiveObservational research has indicated a potential link between dietary salt intake and susceptibility to dementia. However, it is important...
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Pathophysiological Links Between Obesity and Dementia
Obesity is a major global health concern, with prevalence rates rapidly rising due to increased availability of highly processed foods rich in fats...
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Heat-related illness and dementia: a study integrating epidemiological and experimental evidence
BackgroundHeat-related illness (HRI) is commonly considered an acute condition, and its potential long-term consequences are not well understood. We...
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Prevalence and modifiable risk factors for dementia in persons with intellectual disabilities
BackgroundPeople with intellectual disability (ID) without Down syndrome (DS) are presumed to be at higher risk of developing dementia due to their...
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Association of MAFLD and MASLD with all-cause and cause-specific dementia: a prospective cohort study
BackgroundLiver disease and dementia are both highly prevalent and share common pathological mechanisms. We aimed to investigate the associations...
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STEADYNet: Spatiotemporal EEG analysis for dementia detection using convolutional neural network
Dementia is a neuro-degenerative disorder with a high death rate, mainly due to high human error, time, and cost of the current clinical diagnostic...
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Plasma trimethylamine N-oxide (TMAO): associations with cognition, neuroimaging, and dementia
BackgroundThe gut-derived metabolite Trimethylamine N-oxide (TMAO) and its precursors - betaine, carnitine, choline, and deoxycarnitine – have been...
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Paradigm Shift: Multiple Potential Pathways to Neurodegenerative Dementia
Neurodegenerative dementia can result from multiple underlying abnormalities, including neurotransmitter imbalances, protein aggregation, and other...