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Altered DTI scalars in the hippocampus are associated with morphological and structural changes after traumatic brain injury
Blunt and diffuse injury is a highly prevalent form of traumatic brain injury (TBI) which can result in microstructural alterations in the brain. The...
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Detection of mild cognitive impairment in Parkinson’s disease using gradient boosting decision tree models based on multilevel DTI indices
BackgroundCognitive dysfunction is the most common non-motor symptom in Parkinson’s disease (PD), and timely detection of a slight cognitive decline...
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MRI Aspects: Conventional, SWI, and DTI
This chapter will focus on structural magnetic resonance imaging (MRI) in degenerative cerebellar ataxias. First, we will briefly introduce MRI pulse... -
Spectrum-sine interpolation framework for DTI processing
Diffusion tensor imaging (DTI) data interpolation is important for DTI processing, which could affect the precision and computational complexity in...
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DTI Atlases Evaluations
The cerebral atlas of diffusion tensor magnetic resonance image (DT-MRI, shorted as DTI) is one of the key issues in neuroimaging research. It is...
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DTI of chronic spinal cord injury in children without MRI abnormalities (SCIWOMR) and with pathology on MRI and comparison to severity of motor impairment
Study designThis investigation was a cohort study that included: 36 typically developing (TD) children and 19 children with spinal cord lesions who...
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A property-response perspective on modern toxicity assessment and drug toxicity index (DTI)
Toxicity related failures in drug discovery and clinical development have motivated scientists and regulators to develop a wide range of in-vitro,...
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Disrupted frontostriatal connectivity in primary insomnia: a DTI study
Dysfunction of the sleep-wake transition is considered to be associated with the pathology of patients with primary insomnia (PI). Previous animal...
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The hippocampal region is necessary for text comprehension and memorization: a combined VBM/DTI study in neuropsychological patients
According to the Construction-Integration model (Kintsch
1988 ; Kintsch1998 ), two forms of representation are activated during the reading and the... -
Assessment of Mechanically Induced Changes in Helical Fiber Microstructure Using Diffusion Tensor Imaging
Noninvasive methods to detect microstructural changes in collagen-based fibrous tissues are necessary to differentiate healthy from damaged tissues...
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Correlation of Cognitive Reappraisal and the Microstructural Properties of the Forceps Minor: A Deductive Exploratory Diffusion Tensor Imaging Study
Cognitive reappraisal (CR) is a mechanism for emotion regulation, and the prefrontal cortex (PFC) plays a central role in the regulation of emotions....
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Diffusion along perivascular spaces as marker for impairment of glymphatic system in Parkinson’s disease
The brain glymphatic system is involved in the clearance of misfolding α-synuclein, the impaired glymphatic system may contribute to the progression...
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Brain microstructural abnormalities in patients with Wilson’s disease: A systematic review of diffusion tenor imaging studies
IntroductionWilson’s disease (WD) is an autosomal recessive that can lead to high copper concentrations and copper accumulation in bodily organs,...
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The relationship between amyloid pathology, cerebral small vessel disease, glymphatic dysfunction, and cognition: a study based on Alzheimer’s disease continuum participants
BackgroundGlymphatic dysfunction is a crucial pathway for dementia. Alzheimer’s disease (AD) pathologies co-existing with cerebral small vessel...
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Brain white matter microstructural alterations in patients with systemic lupus erythematosus: an automated fiber quantification study
This study aimed to identify damaged segments of brain white matter fiber tracts in patients with systemic lupus erythematosus (SLE) using diffusion...
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A single mild juvenile TBI in male mice leads to regional brain tissue abnormalities at 12 months of age that correlate with cognitive impairment at the middle age
Traumatic brain injury (TBI) has the highest incidence amongst the pediatric population and its mild severity represents the most frequent cases....
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Cerebellar Microstructural Abnormalities in Obsessive–Compulsive Disorder (OCD): a Systematic Review of Diffusion Tensor Imaging Studies
Previous neuroimaging studies have suggested that obsessive–compulsive disorder (OCD) is associated with altered resting-state functional...
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Diverging prefrontal cortex fiber connection routes to the subthalamic nucleus and the mesencephalic ventral tegmentum investigated with long range (normative) and short range (ex-vivo high resolution) 7T DTI
Uncertainties concerning anatomy and function of cortico-subcortical projections have arisen during the recent years. A clear distinction between...
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Influences of amyloid-β and tau on white matter neurite alterations in dementia with Lewy bodies
Dementia with Lewy bodies (DLB) is a neurodegenerative condition often co-occurring with Alzheimer’s disease (AD) pathology. Characterizing white...
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Berberine improves cognitive impairment by alleviating brain atrophy and promoting white matter reorganization in diabetic db/db mice: a magnetic resonance imaging-based study
Diabetic cognitive impairment is a common complication in type 2 diabetes. Berberine (BBR) is an isoquinoline alkaloid that has been shown to have...