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Targeting the conserved coronavirus octamer motif GGAAGAGC is a strategy for the development of coronavirus vaccine
BackgroundCoronaviruses are pathogens of humans and animals that cause widespread and costly diseases. The development of effective strategies to...
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2019 Novel Coronavirus
COVID-19 is a viral infection that originated in the Wuhan province of China and subsequently exponentially spread worldwide in 230 countries and...
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Biological characterization of coronavirus noncanonical transcripts in vitro and in vivo
BackgroundIn addition to the well-known coronavirus genomes and subgenomic mRNAs, the existence of other coronavirus RNA species, which are...
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Coronavirus Entry Inhibitors
Coronaviruses (CoVs) are enveloped RNA viruses that widely exist in the environment. Several CoVs possess a strong ability to infect humans, termed...
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Middle East Respiratory Syndrome Coronavirus (MERS-CoV)
Ten years after the severe SARS-CoV outbreak in 2002, another lethal coronavirus outbreak was reported in Middle Eastern countries. Based on the...
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Identification of the protein coding capability of coronavirus defective viral genomes by mass spectrometry
During coronavirus infection, in addition to the well-known coronavirus genomes and subgenomic mRNAs, an abundance of defective viral genomes (DVGs)...
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In search of a pan-coronavirus vaccine: next-generation vaccine design and immune mechanisms
Members of the coronaviridae family are endemic to human populations and have caused several epidemics and pandemics in recent history. In this...
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Genetic Associations with Coronavirus Susceptibility and Disease Severity
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the coronavirus disease 2019 (COVID-19) global public health...
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Coronavirus and the Cytoskeleton of Virus-Infected Cells
The cytoskeleton, which includes actin filaments, microtubules, and intermediate filaments, is one of the most important networks in the cell and...
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Unveiling the biology of defective viral genomes in vitro and in vivo: implications for gene expression and pathogenesis of coronavirus
BackgroundDefective viral genome (DVG) is a truncated version of the full-length virus genome identified in most RNA viruses during infection. The...
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Structure and Dynamics of Depressive Disorders in Patients after the Novel Coronavirus Infection (COVID-19)
Objective . To analyze the dynamics of depressive disorders in patients who have had infections with the novel coronavirus (COVID-19). Materials and...
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A suitable model to investigate acute neurological consequences of coronavirus infection
Objective and designThe present study aimed to investigate the neurochemical and behavioral effects of the acute consequences after coronavirus...
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Mechanism and treatment of olfactory dysfunction caused by coronavirus disease 2019
Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since the...
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What Is the Impact of the Novel Coronavirus and the Vaccination on Guillain–Barre Syndrome?
The COVID-19 pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has resulted in devastating medical and economic...
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Coronavirus infection in chemosensory cells
Clinical manifestations of human coronavirus (HCoV)-related diseases are mostly related to the respiratory system, although secondary complications...
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Prevalence of natural feline coronavirus infection in domestic cats in Fujian, China
Only few studies have investigated the prevalence of feline coronavirus (FCoV) infection in domestic cats in Fujian, China. This is the first study...
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The Coronavirus Disease 2019 (COVID-19) Pandemic
SARS-CoV-2, the coronavirus that causes COVID-19, emerged in late 2019 and caused a historic pandemic. In 3 years, it has infected half the world’s...
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Transcriptional differences between coronavirus disease 2019 and bacterial sepsis
BackgroundCoronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, has led to major public health crises...
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Quantitative assay to analyze neutralization and inhibition of authentic Middle East respiratory syndrome coronavirus
To date, there is no licensed vaccine for Middle East respiratory syndrome coronavirus (MERS-CoV). Therefore, MERS-CoV is one of the diseases...
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Inducible nitric oxide synthase deficiency promotes murine-β-coronavirus induced demyelination
BackgroundMultiple sclerosis (MS) is characterized by neuroinflammation and demyelination orchestrated by activated neuroglial cells, CNS...
