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Chemokines in Cancer Therapy
Chemokines are small cell signalling proteins corresponding to family of cytokines that aid in movement of leukocytes. They are low-molecular-weight...
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How chemokines organize the tumour microenvironment
For our immune system to contain or eliminate malignant solid tumours, both myeloid and lymphoid haematopoietic cells must not only extravasate from...
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Expression of 10 circulating cytokines/chemokines in HBV-related liver disease
BackgroundCytokines/chemokines play essential roles in the occurrence and progression of hepatitis B virus (HBV) infection. This study aimed to...
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Chemokines and Chemokine Receptors in Cancer: An Update
The chemokine family is composed of small chemotactic cytokines and receptors that mediate the infiltration of various immune cells. According to the...
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Circulating Chemokines and Short- and Long-Term Outcomes After Ischemic Stroke
Chemokines are vital in post-cerebral ischemia inflammatory reactions. We investigate the possible relationship between plasma chemokines and...
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Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course
Infection with severe acute respiratory syndrome coronavirus 2 associates with diverse symptoms, which can persist for months. While antiviral...
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Cytokines and Chemokines in Tumor Growth and Progression
The significance of cytokines as signaling molecules, which has long been acknowledged, is expanding as a result of their connection to malignancies...
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Curcumin and chemokines: mechanism of action and therapeutic potential in inflammatory diseases
Chemokines belong to the family of cytokines with chemoattractant properties that regulate chemotaxis and leukocyte migration, as well as the...
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Blood and CSF chemokines in Alzheimer’s disease and mild cognitive impairment: a systematic review and meta-analysis
ObjectiveChemokines, which are chemotactic inflammatory mediators involved in controlling the migration and residence of all immune cells, are...
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The Blood Contents of Pro-Inflammatory Chemokines in Patients with a First Episode of Schizophrenia before Therapy
Abstract —The role of chemokines involved in the processes of neuroinflammation is not well understood in schizophrenia, especially in patients with...
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Role of Chemokines in the Development and Progression of Alzheimer’s Disease
Alzheimer’s disease (AD) is a progressive neurogenerative disorder manifested by gradual memory loss and cognitive decline due to profound damage of...
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Acute stress transiently activates macrophages and chemokines in cervical lymph nodes
Acute restraint stress (RS) is routinely used to study the effects of psychological and/or physiological stress. We evaluated the impact of RS on...
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The roles of CC chemokines in response to radiation
Radiotherapy is an effective regimen for cancer treatment alone or combined with chemotherapy or immunotherapy. The direct effect of radiotherapy...
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Prognostic and Diagnostic Significance of Chemokines and Cytokines in Cancer
A cooperated, powerful, but self-constrained immune reaction to a goal antigen is produced by the immune system's cells in conjunction with...
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The chemokines CXCL8 and CXCL12: molecular and functional properties, role in disease and efforts towards pharmacological intervention
Chemokines are an indispensable component of our immune system through the regulation of directional migration and activation of leukocytes. CXCL8 is...
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Role of Chemokines in Colorectal Cancer
Colorectal cancer (CRC) is one of the most common causes for cancer-related deaths worldwide. Chemokines, structurally related cytokines, are present...
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Interactions of the chemokines CXCL11 and CXCL12 in human tumor cells
BackgroundThe chemokines, CXCL12 and CXCL11, are upregulated in tumors from many organs and control their progression. CXCL12 and CXCL11 affect tumor...
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Immunoprofiling of cytokines, chemokines, and growth factors in female patients with systemic lupus erythematosus– a pilot study
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease affecting different organ systems. This study aimed to determine the...
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Comprehensive analysis of prognostic value and immune infiltration of CXC chemokines in pancreatic cancer
BackgroundThe prognosis of pancreatic cancer is poor, with a 5-year survival rate of less than 10%. Studies have shown that chemokines in the tumour...
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Multiplex Assessment of Serum Chemokines CCL2, CCL5, CXCL1, CXCL10, and CXCL13 Following Traumatic Brain Injury
Chemokines may promote neuroinflammation following traumatic brain injury (TBI), thereby exacerbating secondary injury. This study was designed to...
