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Why Taste Is Pharmacology
The chapter presents an argument supporting the view that taste, defined as the receptor-mediated signaling of taste cells and consequent sensory...
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Novel Cellular Stress Models with Implications in Understanding and Treating ENT Pathologies
Interaction with the world around us requires extracting meaningful signals to guide behaviour. The mammalian senses of olfaction, vision,...
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Efficacy of sodium bicarbonate ingestion strategies for protecting blinding
Sodium bicarbonate (NaHCO 3 ) is a widely researched ergogenic aid, but the optimal blinding strategy during randomised placebo-controlled trials is...
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Neuropeptides in sensory signal processing
Peptides released from trigeminal fibers fulfill well-understood functions in neuroinflammatory processes and in the modulation of nociceptive signal...
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Encoding Taste: From Receptors to Perception
Taste information is encoded in the gustatory nervous system much as in other sensory systems, with notable exceptions. The concept of adequate...
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To flourish or perish: evolutionary TRiPs into the sensory biology of plant-herbivore interactions
The interactions between plants and their herbivores are highly complex systems generating on one side an extraordinary diversity of plant protection...
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Exposure limits for indoor volatile substances concerning the general population: The role of population-based differences in sensory irritation of the eyes and airways for assessment factors
Assessment factors (AFs) are essential in the derivation of occupational exposure limits (OELs) and indoor air quality guidelines. The factors shall...
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The novel high-frequency variant of TRPV3 p.A628T in East Asians showing faster sensitization in response to chemical agonists
TRPV3, a member of the thermosensitive Ca 2+ -permeable TRPV channel subfamily expressed in skin and sensory nerves, is also activated by chemical...
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Taste buds: cells, signals and synapses
The past decade has witnessed a consolidation and refinement of the extraordinary progress made in taste research. This Review describes recent...
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TRPs in Taste and Chemesthesis
TRP channels are expressed in taste buds, nerve fibers, and keratinocytes in the oronasal cavity. These channels play integral roles in transducing...
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Is fat the sixth taste primary? Evidence and implications
Taste is the chemical sense responsible for the detection of non-volatile chemicals in potential foods. For fat to be considered as one of the taste...
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Just how much of what we taste derives from the sense of smell?
It is frequently asserted that somewhere between 75 and 95 % of what we commonly think of as taste actually comes from the sense of smell. However,...
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TRP Channels as Targets for Modulation of Taste Transduction
The sense of taste endows organisms with the ability to distinguish nutritious from potentially harmful food components and to orchestrate adaptive...
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Peripheral thermosensation in mammals
Our ability to perceive temperature is crucial: it enables us to swiftly react to noxiously cold or hot objects and helps us to maintain a constant...
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TRPV3
Transient receptor potential vanilloid-3 (TRPV3) is a Ca2+-permeable nonselective cation channel widely expressed in skin keratinocytes, as well as...
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Orosensory Perception
This chapter provides an introduction to the sensory systems which determine human perception of foods. Since the same sensory systems are stimulated...
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Sensory irritation as a basis for setting occupational exposure limits
There is a need of guidance on how local irritancy data should be incorporated into risk assessment procedures, particularly with respect to the...
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What Do We Really Know and What Do We Need to Know: Some Controversies, Perspectives, and Surprises
TRP channels comprise one of the most rapid growing research topics in ion channel research, in fields related to ion channels including...
