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Cerebrospinal fluid-based spatial statistics: towards quantitative analysis of cerebrospinal fluid pseudodiffusivity
BackgroundCerebrospinal fluid (CSF) circulation is essential in removing metabolic wastes from the brain and is an integral component of the...
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Cerebrospinal fluid pH regulation
The cerebrospinal fluid (CSF) fills the brain ventricles and the subarachnoid space surrounding the brain and spinal cord. The fluid compartment of...
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Cerebrospinal Fluid Biomarkers in Huntington’s Disease
Huntington’s disease (HD) is a devastating neurodegenerative disorder caused by a CAG repeat expansion mutation in the HTT gene that leads to...
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The first report of Apiotrichum mycotoxinivorans isolation from human cerebrospinal fluid
Fungal infections due to Apiotrichum mycotoxinivorans are clinically rare. Here, we report a case of invasive blood and cerebrospinal fluid infection...
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A Review of Cerebrospinal Fluid Circulation and the Pathogenesis of Congenital Hydrocephalus
The brain’s ventricles are filled with a colorless fluid known as cerebrospinal fluid (CSF). When there is an excessive accumulation of CSF in the...
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Clinical features, cerebrospinal fluid changes, and prognosis in Chinese patients with autoimmune encephalitis
IntroductionAutoimmune encephalitis (AE) is a rare, treatable disease of the central nervous system (CNS) caused by an antibody-related immune...
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Cerebrospinal fluid-contacting neurons: multimodal cells with diverse roles in the CNS
The cerebrospinal fluid (CSF) is a complex solution that circulates around the CNS, and whose composition changes as a function of an animal’s...
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Diagnosis of pediatric central nervous system tumors using methylation profiling of cfDNA from cerebrospinal fluid
Pediatric central nervous system tumors remain challenging to diagnose. Imaging approaches do not provide sufficient detail to discriminate between...
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Cerebrospinal Fluid from Patients After Craniotomy with the Appearance of Interleukin-6 Storm Can Activate Microglia to Damage the Hypothalamic Neurons in Mice
We monitored CSF (cerebrospinal fluid) for Th1/Th2 inflammatory cytokines in a patient with unexplained postoperative disturbance of consciousness...
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Blood pressure lowering enhances cerebrospinal fluid efflux to the systemic circulation primarily via the lymphatic vasculature
BackgroundInside the incompressible cranium, the volume of cerebrospinal fluid is directly linked to blood volume: a change in either will induce a...
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No difference in extra-axial cerebrospinal fluid volumes across neurodevelopmental and psychiatric conditions in later childhood and adolescence
BackgroundWhile autism spectrum disorder has been associated with various organizational and developmental aberrations in the brain, an increase in...
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Buprenorphine plasma and cerebrospinal fluid concentrations in osteoarthritis patients during low-dose transdermal patch dosing
MethodsFifty-six (56) patients scheduled for arthroplasty, received 7-day extended-release buprenorphine transdermal patches (5 µg/h) for five...
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Haptoglobin Attenuates Cerebrospinal Fluid Hemoglobin-Induced Neurological Deterioration in Sheep
Secondary brain injury (SBI) occurs with a lag of several days post-bleeding in patients with aneurysmal subarachnoid hemorrhage (aSAH) and is a...
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Lysosomal and synaptic dysfunction markers in longitudinal cerebrospinal fluid of de novo Parkinson’s disease
Lysosomal and synaptic dysfunctions are hallmarks in neurodegeneration and potentially relevant as biomarkers, but data on early Parkinson’s disease...
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Altered brain expression and cerebrospinal fluid levels of TIMP4 in cerebral amyloid angiopathy
Cerebral amyloid angiopathy (CAA) is a highly prevalent and progressive pathology, involving amyloid-β (Aβ) deposition in the cerebral blood vessel...
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Highly accurate blood test for Alzheimer’s disease is similar or superior to clinical cerebrospinal fluid tests
With the emergence of Alzheimer’s disease (AD) disease-modifying therapies, identifying patients who could benefit from these treatments becomes...
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Red Blood Cells in the Cerebrospinal Fluid Compartment After Subarachnoid Haemorrhage: Significance and Emerging Therapeutic Strategies
Subarachnoid haemorrhage (SAH) is a subtype of stroke that predominantly impacts younger individuals. It is associated with high mortality rates and...
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Learning from cerebrospinal fluid drug-resistant HIV escape-associated encephalitis: a case report
BackgroundIn the era of antiretroviral therapy (ART), central nervous system (CNS) complications in patients with human immunodeficiency virus (HIV)...
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Cerebrospinal fluid penetration of fosfomycin in patients with ventriculitis: an observational study
BackgroundFor treatment of ventriculitis, vancomycin and meropenem are frequently used as empiric treatment but cerebrospinal fluid (CSF) penetration...
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Impact of thermodynamical rotational flow of cerebrospinal fluid in the presence of elasticity
ObjectiveTo explore the experimental justification of cerebrospinal fluid (CSF) amplitude and elastic fluctuations of ventricles, we extend our...
