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Brain Organoid Research
This volume explores multiple methods and approaches used to generate human brain and neuroretinal organoids to address fundamental questions in...
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Investigating nutrient biomarkers of healthy brain aging: a multimodal brain imaging study
The emerging field of Nutritional Cognitive Neuroscience aims to uncover specific foods and nutrients that promote healthy brain aging. Central to...
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Modeling Brain Tumors Using Genetically Edited Brain Organoids
Compared to other parts of the body, tumors in the human central nervous system account for a small proportion of tumors but have a significant...
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The Gliocentric Brain Phenotype Plasticity of the Damaged Brain
The brain is the body’s most vulnerable organ due to the defined roles of neurons within circuits. Neurons are vastly outnumbered by microglia,...
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Link Brain-Wide Projectome to Neuronal Dynamics in the Mouse Brain
Knowledge about the neuronal dynamics and the projectome are both essential for understanding how the neuronal network functions in concert. However,...
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Brain–Computer Interfaces
In the past decades, brain–computer interfaces (BCIs) have been among the fastest-growing technologies and a very prolific research field. Typically,...
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How deep is the brain? The shallow brain hypothesis
Deep learning and predictive coding architectures commonly assume that inference in neural networks is hierarchical. However, largely neglected in...
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Linking Models with Brain Measures
Linking models and brain measures offers a number of advantages over standard analyses. Models that have been evaluated on previous datasets can...
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In Vivo Brain Microdialysis
Many biological molecules in the brain interstitial fluid are involved in neuronal functions. Therefore, measuring the levels of these molecules in...
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Proteomic alterations in the brain and blood–brain barrier during brain Aβ accumulation in an APP knock-in mouse model of Alzheimer’s disease
BackgroundBlood–brain barrier (BBB) dysfunction is supposed to be an early event in the development of Alzheimer’s disease (AD). This study aimed to...
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How to Build a Human Brain
How to Build a Human Braintakes a developmental approach to understanding brain structure and function. It guides readers through the evolution of...
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Blood–brain borders: a proposal to address limitations of historical blood–brain barrier terminology
Many neuroscientists use the term Blood–Brain Barrier (BBB) to emphasize restrictiveness, often equating or reducing the notion of BBB properties to...
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Development of a method for isolating brain capillaries from a single neonatal mouse brain and comparison of proteomic profiles between neonatal and adult brain capillaries
BackgroundThe functions and protein expressions of the blood–brain barrier are changed throughout brain development following birth. This study aimed...
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Brain Leitmotifs The Structure and Activity Patterns of Neuronal Networks
This book tackles the question of why the brain is so difficult to fully understand. In neuroscience, data are acquired and analyzed with astonishing...
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Brain Computational Models
Human brain is a biological tissue, which weighs 1250–1600 gr, with a volume of 1130–1260 cm3, and it totally consists of about more than 2‧1010...
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Regenerative Medicine and Brain Repair
This book presents the latest knowledge, trends, and advances in cell transplantation and innovations in developing microspheres, 3D biomaterial...
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Brain structural covariances in the ageing brain in the UK Biobank
The morphologic properties of brain regions co-vary or correlate with each other. Here we investigated the structural covariances of cortical...
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Subcutaneous injection sites impact brain uptake of blood-brain barrier impermeable paclitaxel
PurposeSystemic absorption is the process of drug movement from the site of drug administration to systemic circulation for therapeutic efficacy....
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Immunohistochemistry of Brain Tissues
Immunohistochemistry (IHC) is the basis of histological or pathological analysis and is widely used to enable the detection and characterization of...
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The Roles of hnRNP Family in the Brain and Brain-Related Disorders
Heterogeneous nuclear ribonucleoproteins (hnRNPs) belong to a complex family of RNA-binding proteins that are essential to control alternative...
