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High Intensity Interval Training can Ameliorate Hypothalamic Appetite Regulation in Male Rats with Type 2 Diabetes: The Role of Leptin
Disruption of leptin (LEP) signaling in the hypothalamus caused by type 2 diabetes (T2D) can impair appetite regulation. The aim of this study was to...
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Appetite ratings and ghrelin concentrations in young adults after administration of a balanced meal. Does sex matter?
BackgroundSex-based differences in appetite ratings have been observed previously. Ghrelin is the only known orexigenic peptide hormone. Sex...
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Discriminative stimulus effects of an imidazolidine-derived appetite suppressant
GYKI-13380 (4-[3-(cyclopentyloxy)-4-methoxybenzyl]-2-imidazolidinone) was synthesized with the idea to incorporate a phenethylamine-like structure...
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From gut microbiota to host appetite: gut microbiota-derived metabolites as key regulators
Feelings of hunger and satiety are the key determinants for maintaining the life of humans and animals. Disturbed appetite control may disrupt the...
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The Neurobiology of Thirst and Sodium Appetite
Water and salt are essential to life on earth. Multicellular terrestrial organisms must obtain water and salt, circulate them to the cells, and... -
Therapeutic applications of melatonin in disorders related to the gastrointestinal tract and control of appetite
Most animals have large amounts of the special substance melatonin, which is controlled by the light/dark cycle in the suprachiasmatic nucleus....
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Central and Peripheral Biomarkers for the Study of Appetite Regulation in Humans
The largest global epidemic in the twenty-first century is obesity, since more than 700 million adults had obesity in 2015. Obesity is a consequence... -
Central and Peripheral Biomarkers for the Study of Appetite Regulation in Humans
The largest global epidemic in the twenty-first century is obesity, since more than 700 million adults had obesity in 2015. Obesity is a consequence... -
Neuroendocrine control of appetite and metabolism
Body homeostasis is predominantly controlled by hormones secreted by endocrine organs. The central nervous system contains several important...
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Gut Microbiome Regulation of Appetite and Role in Neurological Disorders
All human beings need food for energy and survival. Leptin and ghrelin are two of the most powerful peripheral hormones that manage your hunger and... -
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The effect of glutamine supplementation on serum levels of some inflammatory factors, oxidative stress, and appetite in COVID-19 patients: a case–control study
BackgroundMalnutrition is seen in COVID-19 patients, and reducing malnutrition with appropriate therapies may improve these patients' health. This...
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Effect of Bifidobacterium on olanzapine-induced body weight and appetite changes in patients with psychosis
RationaleGut microbiota plays an important role in host metabolism. Antipsychotic drugs can result in metabolic abnormalities. Probiotics may...
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The Pivotal Role of Neuropeptide Crosstalk from Ventromedial-PACAP to Dorsomedial-Galanin in the Appetite Regulation in the Mouse Hypothalamus
We have previously shown that pituitary adenylate cyclase-activating polypeptide (PACAP) in the ventromedial hypothalamus (VMH) enhances feeding...
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The Neurobiology of Thirst and Sodium Appetite
Water and salt are essential to life on earth. Multicellular terrestrial organisms must obtain water and salt, circulate them to the cells, and... -
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Appetite-enhancing effects of inhaling cinnamon, clove, and fennel essential oils containing phenylpropanoid analogues
Cinnamon, clove, and fennel are commonly used as spices and herbal medicines, and one of their medicinal uses is as aromatic stomachics. We...
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A neural basis for tonic suppression of sodium appetite
Sodium appetite is a powerful form of motivation that can drive ingestion of high, yet aversive concentrations of sodium in animals that are depleted...