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Alzheimer’s Disease Methods and Protocols
This volume explores the latest techniques used to study the human brain towards understanding Alzheimer’s Disease and related neurodegenerative...
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Alzheimer’s Disease Research What Has Guided Research So Far and Why It Is High Time for a Paradigm Shift
This book highlights the key phases and central findings of Alzheimer’s Disease research since the introduction of the label ‘Alzheimer’s Disease’ in...
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Alzheimer’s Disease
Alzheimer’s disease is a dramatic pathological occurrence for the patient, his family, caregivers and doctors.
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Biomarkers for Alzheimer’s Disease Drug Development
This fully updated volume provides an up-to-date and comprehensive overview of the current state of technologies helping to accelerate Alzheimer’s...
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Age, sex and Alzheimer’s disease: a longitudinal study of 3xTg-AD mice reveals sex-specific disease trajectories and inflammatory responses mirrored in postmortem brains from Alzheimer’s patients
BackgroundAging and sex are major risk factors for developing late-onset Alzheimer’s disease. Compared to men, women experience worse...
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Deciphering Drug Targets for Alzheimer’s Disease
This book explains the fundamental characteristics and biofunctionality of Alzheimer’s Disease drug targets and provides up-to-date information on...
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Alzheimer’s Disease Research After 1945: The Recommencement
Scientific publishing platforms such as PubMed feature an overwhelming number of entries on “Alzheimer’s disease” compared to other human...
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The Glutamatergic Hypothesis of Alzheimer’s Disease
Glutamate (L-glutamate, L-glutamic acid) is an amino acid and building block of peptides and proteins. In addition, glutamate is the most abundant...
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Drug Delivery Strategies in Alzheimer’s Disease
Over the past few decades, a concern over neurodegenerative disorders is growing proportionately with age, changing lifestyles, hereditary...
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Alzheimer’s Research Goes Deeper: Ultrastructural Electron Microscopy Studies
With the introduction of electron microscopy (EM), the nerve cell’s ultrastructure could be resolved. EM was applied to postmortem tissue of...
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Metabolic Disease and Alzheimer’s Disease
Age-related diseases (ARDs) include inflammatory atherosclerosis and cardiovascular disease in coronary artery disease (CAD), hypertension, type 2...
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Novel Nutraceutical Milk Compound in Alzheimer’s Prevention
Alzheimer’s disease gradually affects the nerves in the brain and leads to gradual memory loss. It is prevalent among the elderly and has negative...
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Cathepsin B abundance, activity and microglial localisation in Alzheimer’s disease-Down syndrome and early onset Alzheimer’s disease; the role of elevated cystatin B
Cathepsin B is a cysteine protease that is implicated in multiple aspects of Alzheimer’s disease pathogenesis. The endogenous inhibitor of this...
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Pathophysiology and Management Approaches in Alzheimer’s Disease
Alzheimer’s disease is recognized as a progressive multifarious neurodegenerative disorder that is pathologically characterized by the deposition of...
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Driving Forces of Alzheimer’s Research Directions
Quite a number of influential factors impact the course of biomedical research. Regarding Alzheimer’s disease, some factors appear to have had a...
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Epigenetic Therapy for Alzheimer’s Disease
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with no effective treatments. Increasing evidence suggests that the epigenetic...
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Gene therapy: an alternative to treat Alzheimer’s disease
Alzheimer’s disease (AD), a neuro-degenerative disease that primarily affects the elderly, is a worldwide phenomenon. Loss of memory, cognitive...
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Alzheimer’s Research Gains Momentum and Spreads Out
In the long shadow of Alzheimer’s research into amyloid and tau biology and function, especially in 2002 and the years to follow, many significant...
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Phytoactive drugs used in the treatment of Alzheimer’s disease and dementia
The prevalence of Alzheimer’s disease and other forms of dementia is increasing worldwide, and finding effective treatments for these conditions is a...
