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Microbial underdogs: exploring the significance of low-abundance commensals in host-microbe interactions
Our understanding of host-microbe interactions has broadened through numerous studies over the past decades. However, most investigations primarily...
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Relative abundance data can misrepresent heritability of the microbiome
BackgroundHost genetics can shape microbiome composition, but to what extent it does, remains unclear. Like any other complex trait, this important...
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Effect of Apolipoprotein E isoforms on the Abundance and Function of P-glycoprotein in Human Brain Microvascular Endothelial Cells
BackgroundIndividuals with Alzheimer’s disease (AD) often require many medications; however, these medications are dosed using regimens recommended...
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Effects of rodent abundance on ticks and Borrelia: results from an experimental and observational study in an island system
BackgroundLyme borreliosis is the most common tick-borne disease in Europe and is often caused by Borrelia afzelii, which is transmitted by Ixodes...
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Presence and abundance of malaria vector species in Miami-Dade County, Florida
BackgroundMalaria outbreaks have sporadically occurred in the United States, with Anopheles quadrimaculatus serving as the primary vector in the...
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Abundance and diversity of Culicoides Latreille (Diptera: Ceratopogonidae) in southern Ontario, Canada
BackgroundCulicoides Latreille (Diptera: Ceratopogonidae) is a genus of hematophagous midges feeding on various vertebrate hosts and serving as a...
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The species and abundance of gut bacteria both positively impact Phortica okadai behavior
BackgroundGut bacteria, which serve as essential modulators, exert a significant impact on insect physiology and behavior and have substantial...
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CD4 T cell epitope abundance in ferritin core potentiates responses to hemagglutinin nanoparticle vaccines
Nanoparticle vaccines based on H. pylori ferritin are increasingly used as a vaccine platform for many pathogens, including RSV, influenza, and...
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Pendrin abundance, subcellular distribution, and function are unaffected by either αENaC gene ablation or by increasing ENaC channel activity
The intercalated cell Cl − /HCO 3 − exchanger, pendrin, modulates ENaC subunit abundance and function. Whether ENaC modulates pendrin abundance and...
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Characterization of environmental drivers influencing the abundance of Anopheles maculipennis complex in Northern Italy
BackgroundIn Italy, malaria was endemic until the 1970s, when it was declared eradicated by WHO. Nowadays, with the persistence of competent mosquito...
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Global abundance patterns, diversity, and ecology of Patescibacteria in wastewater treatment plants
BackgroundMicroorganisms are responsible for nutrient removal and resource recovery in wastewater treatment plants (WWTPs), and their diversity is...
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Environmental influence on abundance and infection patterns of snail intermediate hosts of liver and intestinal flukes in North and Central Vietnam
Liver and intestinal flukes (LIF) are important groups of foodborne zoonotic trematodes (FZTs) in Southeast Asia, including Vietnam. Their complex...
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Increased Fusobacterium tumoural abundance affects immunogenicity in mucinous colorectal cancer and may be associated with improved clinical outcome
AbstractThere is currently an urgent need to identify factors predictive of immunogenicity in colorectal cancer (CRC). Mucinous CRC is a distinct...
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DYNLL1 transcript abundance decreases during oocyte and follicular growth and is associated with fertility in mice
DNA repair efficiency is an important determinant of oocyte quality and female fertility. DYNLL1 (Dynein light chain 1) plays a part in DNA...
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Anopheles larval habitats seasonality and environmental factors affecting larval abundance and distribution in Arjo-Didessa sugar cane plantation, Ethiopia
BackgroundWater resource development projects are essential for increasing agricultural productivity and ensuring food security. However, these...
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Cathepsin B abundance, activity and microglial localisation in Alzheimer’s disease-Down syndrome and early onset Alzheimer’s disease; the role of elevated cystatin B
Cathepsin B is a cysteine protease that is implicated in multiple aspects of Alzheimer’s disease pathogenesis. The endogenous inhibitor of this...
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Detection of low-frequency mutations in clinical samples by increasing mutation abundance via the excision of wild-type sequences
The efficiency of DNA-enrichment techniques is often insufficient to detect mutations that occur at low frequencies. Here we report a DNA-excision...
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Seasonal variation in abundance and blood meal sources of primary and secondary malaria vectors within Kilombero Valley, Southern Tanzania
BackgroundExisting control tools have significantly reduced malaria over the past two decades. However, progress has been stalled due to increased...
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The Abundance of KRAS and RAS Gene Mutations in Cancer
Mutant forms of the RAS genes KRAS, NRAS, and HRAS are important and common drivers of cancer. Recently, two independent teams that integrated cancer...