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A cervical cancer biorepository for pharmacogenomics research in Zimbabwe
BackgroundResearch infrastructures such as biorepositories are essential to facilitate genomics and its growing applications in health research and...
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Genomic landscape, immune characteristics and prognostic mutation signature of cervical cancer in China
PurposeThis study aimed to analyse the genomic alteration profiles and immune characteristics of a cohort of Chinese cervical cancer patients to...
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Impact of NLRP3 gene polymorphisms (rs10754558 and rs10733113) on HPV infection and cervical cancer in southern Chinese population
ObjectiveMutations in the NLRP3gene have previously been linked to certain forms of cancer, but there have not been any specific studies examining...
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Vaginal microbiome community state types and high-risk human papillomaviruses in cervical precancer and cancer in North-central Nigeria
BackgroundHigh risk human papillomaviruses (HR-HPV) have a causal role in cervical oncogenesis, and HIV-mediated immune suppression allows HR-HPV to...
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Failure to follow up abnormal test results associated with cervical cancer in primary and ambulatory care: a systematic review
BackgroundCervical cancer is a preventable and treatable form of cancer yet continues to be the fourth most common cancer among women globally....
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Epidemiology and survival outcomes of HIV-associated cervical cancer in Nigeria
IntroductionInvasive cervical cancer (ICC) is an HIV-associated cancer that is preventable and precancerous stages including early ICC stages could...
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Vaccination and screening strategies to accelerate cervical cancer elimination in Norway: a model-based analysis
BackgroundExperts have proposed an ‘EVEN FASTER’ concept targeting age-groups maintaining circulation of human papillomavirus (HPV). We explored...
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Baseline knowledge on risk factors, symptoms and intended behavior of women and men towards screening and treatment of cervical cancer in rural Uganda: a cross-sectional study
BackgroundKnowledge of risk factors and symptoms of cervical cancer has been found to promote uptake of screening of cervical cancer. Most...
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MiR-1254 suppresses the proliferation and invasion of cervical cancer cells by modulating CD36
BackgroundThis study aimed to elucidate the roles of miR-1254 in cervical cancer progression and to explore the underlying mechanisms.
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The linkage of NF-κB signaling pathway-associated long non-coding RNAs with tumor microenvironment and prognosis in cervical cancer
BackgroundNF-κB signaling pathway participate closely in regulating inflammation and immune response in many cancers. Long non-coding RNAs (lncRNAs)...
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Determinants of cervical cancer screening utilization among women attending health facilities of Dessie town, Northeast Ethiopia
IntroductionDespite the higher burden of cervical cases, screening programs in highly affected developing countries remained low. This made the...
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FAT4 overexpression promotes antitumor immunity by regulating the β-catenin/STT3/PD-L1 axis in cervical cancer
BackgroundFAT4 (FAT Atypical Cadherin 4) is a member of the cadherin-associated protein family, which has been shown to function as a tumor...
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Cervical cancer screening and predictors of screening by diabetes status
PurposeWomen with diabetes have lower survival rates after a cervical cancer diagnosis compared to women without diabetes. Pap smears and human...
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YAP/TAZ-TEAD activity promotes the malignant transformation of cervical intraepithelial neoplasia through enhancing the characteristics and Warburg effect of cancer stem cells
A number of studies have confirmed that Yes-associated protein (YAP)/transcriptional co-activator with PDZ-binding motif (TAZ)-transcriptional...
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DNA methylation-based detection and prediction of cervical intraepithelial neoplasia grade 3 and invasive cervical cancer with the WID™-qCIN test
BackgroundCervical screening using primary human papilloma virus (HPV) testing and cytology is being implemented in several countries. Cytology as...
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Construction of a CCL20-centered circadian-signature based prognostic model in cervical cancer
BackgroundRather low vaccination rates for Human papillomavirus (HPV) and pre-existing cervical cancer patients with limited therapeutic strategies...
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Sociodemographic characteristics and their association with survival in women with cervical cancer
BackgroundIn 2020, the highest incidence and mortality from cervical cancer (CC) were detected in low and middle-income countries. CC remains a...
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Survival status and predictors of mortality among cervical cancer patients at oncologic centers in Addis Ababa, Ethiopia: a follow up study
BackgroundCervical cancer (CC) ranks as the third most commonly diagnosed cancer and the fourth leading cause of cancer-related deaths among women...
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The WID-CIN test identifies women with, and at risk of, cervical intraepithelial neoplasia grade 3 and invasive cervical cancer
BackgroundCervical screening is transitioning from primary cytology to primary human papillomavirus (HPV) testing. HPV testing is highly sensitive...
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Factors related to knowledge, attitudes, and behaviors regarding cervical cancer among Yemeni women
BackgroundCervical cancer (CxCa), although preventable, is still among the most prevalent cancers in women. Mortality from this cancer is high,...
