Search
Search Results
-
Comparison of the effect of autoclaved and non-autoclaved live soil exposure on the mouse immune system
Background. Lack of exposure to the natural microbial diversity of the environment has been linked to dysregulation of the immune system and numerous...
-
Ileal inflammation is reduced due to treatment with a metalloprotease from BmooMP-α-I snake venom in an experimental model of Toxoplasma gondii infection
The selection process for advanced therapies in patients with inflammatory bowel diseases (IBDs) must prioritize safety, especially when considering...
-
Inhibition of caspase pathways limits CD4+ T cell loss and restores host anti-retroviral function in HIV-1 infected humanized mice with augmented lymphoid tissue
The study of HIV infection and pathogenicity in physical reservoirs requires a biologically relevant model. The human immune system (HIS) mouse is an...
-
The Specifics of Adrenergic Innervation of Lymph Nodes from Different Body Regions in Young, Mature, and Old Animals
Adrenergic innervation in the tissue of the cervical, mesenteric, and popliteal lymph nodes in rats of different age groups (from 2-45 days to 24...
-
Lymphatic endothelial cells of the lymph node
The influx and efflux of cells and antigens to and from the draining lymph nodes largely take place through the subcapsular, cortical and medullary...
-
Correlation Analysis of Morphological Changes of Structural and Functional Areas of Mesenteric Lymph Nodes with Cytokines of Lymph of Thoracic Lymphatic Duct in Experimental Breast Cancer
We performed a correlation analysis of the morphometric parameters of mesenteric lymph nodes and cytokine content in the lymph of thoracic duct in...
-
Chronic oral exposure to low-concentration fumonisin B2 significantly exacerbates the inflammatory responses of allergies in mice via inhibition of IL-10 release by regulatory T cells in gut-associated lymphoid tissue
Contamination with fumonisins produced by Fusarium spp. is rapidly growing in both developing and developed countries. The purpose of this study was...
-
Undifferentiated sarcomatoid carcinoma of the pancreas-a single-institution experience with 23 cases
BackgroundThe clinical course and surgical outcomes of undifferentiated sarcomatoid carcinoma of the pancreas (USCP) remain poorly characterized...
-
B-Cell Commitment to IL-10 Production: The VertX Il10egfp Mouse
Although the inflammatory cytokine IL-10 is pivotal in regulatory B-cell function, detecting IL-10-producing B cells by intracellular IL-10 staining...
-
Spatial phenotyping of nodular lymphocyte predominant Hodgkin lymphoma and T-cell/histiocyte-rich large B-cell lymphoma
Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is a rare lymphoma with sparse tumor B-cells and a favorable prognosis. Variant growth...
-
The Immunological Importance of the Mesentery
The mesentery contains large amounts of adipocytes and is actively involved in the storage of lipids as well as the release of various adipokines...
-
The impact of HIV infection on the frequencies, function, spatial localization and heterogeneity of T follicular regulatory cells (TFRs) within human lymph nodes
BackgroundHIV eradication efforts have been unsuccessful partly due to virus persistence in immune sanctuary sites such as germinal centres within...
-
Lymph node stromal cells: cartographers of the immune system
Lymph nodes (LNs) are strategically positioned at dedicated sites throughout the body to facilitate rapid and efficient immunity. Central to the...
-
Morphological Study of Mesenteric Lymph Nodes in Rats with Experimental Breast Cancer Treated with Fragmented Double-Stranded DNA
We performed a morphometric analysis of mesenteric lymph nodes in rats with breast cancer induced by administration of N-methyl-N-nitrosourea. The...
-
MSCs mediate long-term efficacy in a Crohn’s disease model by sustained anti-inflammatory macrophage programming via efferocytosis
Mesenchymal stem cells (MSCs) are novel therapeutics for the treatment of Crohn’s disease. However, their mechanism of action is unclear, especially...
-
Gα13 restricts nutrient driven proliferation in mucosal germinal centers
Germinal centers (GCs) that form in mucosal sites are exposed to gut-derived factors that have the potential to influence homeostasis independent of...
-
Intestinal-derived ILCs migrating in lymph increase IFNγ production in response to Salmonella Typhimurium infection
Innate lymphoid cells (ILCs) are enriched in mucosae and have been described as tissue-resident. Interestingly, ILCs are also present within lymph...
-
Hypofractionated radiotherapy for refractory or relapsed aggressive B-cell lymphoma in the rituximab era
BackgroundRadiotherapy (RT) is an effective and available local treatment for patients with refractory or relapsed (R/R) aggressive B-cell lymphomas....
-
Induction of bronchus-associated lymphoid tissue is an early life adaptation for promoting human B cell immunity
Infants and young children are more susceptible to common respiratory pathogens than adults but can fare better against novel pathogens like severe...
-
The Role of Surgery in Managing Primary and Metastatic Colorectal Cancer
The surgical management of metastatic colorectal cancer (CRC) has evolved dramatically over the last few decades. Proper lymph node evaluation is...
