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Development of Functional Properties in the Early Visual System: New Appreciations of the Roles of Lateral Geniculate Nucleus
In the years following Hubel and Wiesel’s first reports on ocular dominance plasticity and amblyopia, much attention has been focused on... -
Vision for action: thalamic and cortical inputs to the macaque superior parietal lobule
The dorsal visual stream, the cortical circuit that in the primate brain is mainly dedicated to the visual control of actions, is split into two...
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The regulation of the pedunculopontine tegmental nucleus in sleep–wake states
The pedunculopontine tegmental nucleus (PPTg) plays a vital role in sleep/wake states. There are three main kinds of heterogeneous neurons involved:...
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Cell death in the lateral geniculate nucleus, and its possible relationship with nicotinic receptors and sudden infant death syndrome (SIDS)
The role of the lateral geniculate nucleus (LGN) in vision has been extensively studied, yet its extraretinal capacities are still being...
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The Wake Promoting Role of the Mediodorsal Thalamic Nuclei in Rat
Mediodorsal thalamic nucleus (MD) is a higher order thalamic nucleus and plays an important role in memory, olfaction, cognitive functions and sleep...
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Processing of sensory, painful and vestibular stimuli in the thalamus
ObjectivesThe thalamus plays an important role in the mediation and integration of various stimuli (e.g., somatosensory, pain, and vestibular)....
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Activation patterns in male and female forebrain circuitries during food consumption under novelty
The influence of novelty on feeding behavior is significant and can override both homeostatic and hedonic drives due to the uncertainty of potential...
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Input-output specific orchestration of aversive valence in lateral habenula during stress dynamics
Stress has been considered as a major risk factor for depressive disorders, triggering depression onset via inducing persistent dysfunctions in...
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Cerebellar Thalamic and Thalamocortical Projections
Although it is well known that the major output of the cerebellum is directed to the thalamus and ultimately to the cerebral cortex, the anatomical... -
Leveling up: a long-range olivary projection to the medial geniculate without collaterals to the central nucleus of the inferior colliculus in rats
The medial nucleus of the trapezoid body (MNTB) is one of the monaural cell groups situated within the superior olivary complex (SOC), a...
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Molecular Profiling of VGluT1 AND VGluT2 Ventral Subiculum to Nucleus Accumbens Shell Projections
The nucleus accumbens shell is a critical node in reward circuitry, encoding environments associated with reward. Long-range inputs from the ventral...
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Identifying the midline thalamus in humans in vivo
The midline thalamus is critical for flexible cognition, memory, and stress regulation in humans and its dysfunction is associated with several...
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Neuronal and glial vulnerability of the suprachiasmatic nucleus in tauopathies: evidence from human studies and animal models
Tauopathies, a group of neurodegenerative diseases that includes Alzheimer’s disease, commonly lead to disturbances in sleep-wake patterns and...
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Nucleus Reuniens: Circuitry, Function, and Dysfunction
The nucleus reuniens (RE) of the ventral midline thalamus is intimately connected with forebrain structures involved in higher-order functions and... -
Connections of the mouse subfornical region of the lateral hypothalamus (LHsf)
The lateral hypothalamus is a major integrative hub with a complex architecture characterized by intricate and overlapping cellular populations...
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Whole-brain connections of glutamatergic neurons in the mouse lateral habenula in both sexes
BackgroundThe lateral habenula (LHb) is an epithalamus nucleus that is evolutionarily conserved and involved in various physiological functions, such...
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Convergence of monosynaptic inputs from neurons in the brainstem and forebrain on parabrachial neurons that project to the paraventricular nucleus of the thalamus
The paraventricular nucleus of the thalamus (PVT) projects to areas of the forebrain involved in regulating behavior. Homeostatic challenges and...
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Recruitment of hippocampal and thalamic pathways to the central amygdala in the control of feeding behavior under novelty
It is adaptive to restrict eating under uncertainty, such as during habituation to novel foods and unfamiliar environments. However, sustained...
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Metabotropic glutamate group II receptor activation in the ventrolateral dorsal striatum suppresses incentive motivation for cocaine in rats
RationaleAfter a history of intermittent cocaine intake, rats develop patterns of drug use characteristic of substance use disorder. The dorsal...
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Downregulation of CDK5 signaling in the dorsal striatum alters striatal microcircuits implicating the association of pathologies with circadian behavior in mice
Dysfunction of striatal dopaminergic circuits has been implicated in motor impairment and Parkinson’s disease (PD)-related circadian perturbations...