Skip to main content
SpringerLink
Log in

The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS): an interface between energy and signal transduction

  • Review
  • Published:
Journal of the Iranian Chemical Society Aims and scope Submit manuscript

Abstract

The bacterial phosphoenolpyruvate (PEP): sugar phosphotransferase system (PTS) mediates the uptake and phosphorylation of carbohydrates, and is involved in signal transduction. It comprises two general phosphotransferase proteins (EI and HPr) and a—species dependent—variable number of sugar-specific enzyme II complexes (IIA, IIB, IIC). EI and HPr transfer phosphoryl groups from PEP to the IIA units. IIA and IIB sequentially transfer phosphates to the sugar, which is translocated by the IIC unit. The ratio of phosphorylated to non-phosphorylated IIA and IIB varies with transport activity, and the phosphorylation state of some of the IIA and IIB serves as signal input for regulation of catabolite repression, intermediate metabolism, gene expression and chemotaxis in response to the availability of carbohydrates and PEP (glycolytic activity). PTS occur in about one-third of all eubacteria and in a few archaebacteria but not in animals and plants. Uniqueness and pleiotropic function make the PTS a potential target for anti-infectives. The PTS transporter for mannose is utilized as a gate for the penetration of bacteriophage lambda DNA across, and insertion of certain bacteriocins (small antimicrobial peptides) into the inner membrane. The PTS of Escherichia coli is in the focus of this review, but occasionally comparisons with other species are made. The topics are: History; Modular design of the E. coli PTS; Structure function and catalytic mechanism of the protein modules; Regulation of and by the PTS; The PTS in pathogenicity and virulence; Computational models; Metabolic engineering.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11
Fig. 12
Fig. 13
Fig. 14

Similar content being viewed by others

References

  1. N.D. Meadow, D.K. Fox, S. Roseman, Annu Rev Biochem 59, 497 (1990)

    Article  CAS  Google Scholar 

  2. P.W. Postma, J.W. Lengeler, G.R. Jacobson, Microbiol Rev 57, 543 (1993)

    CAS  Google Scholar 

  3. P.W. Postma, S. Roseman, Biochim Biophys Acta 457, 213 (1976)

    Article  CAS  Google Scholar 

  4. W. Kundig, S. Gosh, S. Roseman, Proc Natl Acad Sci USA 52, 1067 (1964)

    Article  CAS  Google Scholar 

  5. J. Deutscher, C. Francke, P.W. Postma, Microbiol Mol Biol Rev 70, 939 (2006)

    Article  CAS  Google Scholar 

  6. S. Basu, Glycoconj J 20, 7 (2003)

    Article  Google Scholar 

  7. K.N. Gracy, Biochem Biophys Res Commun 300, 5 (2003)

    Article  Google Scholar 

  8. R.D. Barabote, M.H. Saier Jr, Microbiol Mol Biol Rev 69, 608 (2005)

    Article  CAS  Google Scholar 

  9. G.L. Lorca, R.D. Barabote, V. Zlotopolski, C. Tran, B. Winnen, R.N. Hvorup, A.J. Stonestrom, E. Nguyen, L.W. Huang, D.S. Kim, M.H. Saier Jr, Biochim Biophys Acta 1768, 1342 (2007)

    Article  CAS  Google Scholar 

  10. I.T. Paulsen, L. Nguyen, M.K. Sliwinski, R. Rabus, M.H. Saier Jr, J Mol Biol 301, 75 (2000)

    Article  CAS  Google Scholar 

  11. F. Chauvin, L. Brand, S. Roseman, Res Microbiol 147, 471 (1996)

    Article  CAS  Google Scholar 

  12. A. Fomenkov, A. Valiakhmetov, L. Brand, S. Roseman, Proc Natl Acad Sci USA 95, 8491 (1998)

    Article  CAS  Google Scholar 

  13. C. LiCalsi, T.S. Crocenzi, E. Freire, S. Roseman, J Biol Chem 266, 19519 (1991)

    CAS  Google Scholar 

  14. N.J. Nosworthy, A. Peterkofsky, S. Konig, Y.J. Seok, R.H. Szczepanowski, A. Ginsburg, Biochemistry 37, 6718 (1998)

    Article  CAS  Google Scholar 

  15. P.P. Zhu, R.H. Szczepanowski, N.J. Nosworthy, A. Ginsburg, A. Peterkofsky, Biochemistry 38, 15470 (1999)

    Article  CAS  Google Scholar 

  16. A.E. Oberholzer, P. Schneider, C. Siebold, U. Baumann, B. Erni, J Biol Chem 284, 33169 (2009)

    Article  CAS  Google Scholar 

  17. A. Teplyakov, K. Lim, P.P. Zhu, G. Kapadia, C.C. Chen, J. Schwartz, A. Howard, P.T. Reddy, A. Peterkofsky, O. Herzberg, Proc Natl Acad Sci USA 103, 16218 (2006)

    Article  CAS  Google Scholar 

  18. D.S. Garrett, Y.J. Seok, A. Peterkofsky, G.M. Clore, A.M. Gronenborn, Biochemistry 36, 4393 (1997)

    Article  CAS  Google Scholar 

  19. D.S. Garrett, Y.J. Seok, A. Peterkofsky, A.M. Gronenborn, G.M. Clore, Nat Struct Biol 6, 166 (1999)

    Article  CAS  Google Scholar 

  20. O. Herzberg, C.C. Chen, G. Kapadia, M. McGuire, L.J. Carroll, S.J. Noh, D. Dunaway-Mariano, Proc Natl Acad Sci USA 93, 2652 (1996)

    Article  CAS  Google Scholar 

  21. K. Lim, R.J. Read, C.C. Chen, A. Tempczyk, M. Wei, D. Ye, C. Wu, D. Dunaway-Mariano, O. Herzberg, Biochemistry 46, 14845 (2007)

    Article  CAS  Google Scholar 

  22. L.F. Garcia-Alles, I. Alfonso, B. Erni, Biochemistry 42, 4744 (2003)

    Article  CAS  Google Scholar 

  23. L.F. Garcia-Alles, K. Flükiger, J. Hewel, R. Gutknecht, C. Siebold, S. Schürch, B. Erni, J Biol Chem 277, 6934 (2002)

    Article  CAS  Google Scholar 

  24. C.D. Schwieters, J.Y. Suh, A. Grishaev, R. Ghirlando, Y. Takayama, G.M. Clore, J Am Chem Soc 132, 13026 (2010)

    Article  CAS  Google Scholar 

  25. V. Navdaeva, A. Zurbriggen, S. Waltersperger, P. Schneider, A.E. Oberholzer, P. Bahler, C. Bachler, A. Grieder, U. Baumann, B. Erni, Biochemistry 50, 1184 (2011)

    Article  CAS  Google Scholar 

  26. A.E. Oberholzer, M. Bumann, P. Schneider, C. Bachler, C. Siebold, U. Baumann, B. Erni, J Mol Biol 346, 521 (2005)

    Article  CAS  Google Scholar 

  27. H.V. Patel, K.A. Vyas, R. Savtchenko, S. Roseman, J Biol Chem 281, 17570 (2006)

    Article  CAS  Google Scholar 

  28. O. Misset, M. Brouwer, G.T. Robillard, Biochemistry 19, 883 (1980)

    Article  CAS  Google Scholar 

  29. N. Weigel, M.A. Kukuruzinska, A. Nakazawa, E.B. Waygood, S. Roseman, J Biol Chem 257, 14477 (1982)

    CAS  Google Scholar 

  30. T.A. Karelina, H. Ma, I. Goryanin, O.V. Demin, J Biophys 2011, 579402 (2011)

    CAS  Google Scholar 

  31. V. Venditti, G.M. Clore, J Biol Chem 287, 26989 (2012)

    Article  CAS  Google Scholar 

  32. J.H. Tchieu, V. Norris, J.S. Edwards, M.H. Saier Jr, J Mol Microbiol Biotechnol 3, 329 (2001)

    CAS  Google Scholar 

  33. R. Rabus, J. Reizer, I. Paulsen, M.H. Saier, J Biol Chem 274, 26185 (1999)

    Article  CAS  Google Scholar 

  34. R. Beutler, U. Kämpfer, J. Schaller, B. Erni, Microbiology 147, 249 (2001)

    CAS  Google Scholar 

  35. R. Gutknecht, R. Beutler, L.F. Garcia Alles, U. Baumann, B. Erni, EMBO J 20, 2480 (2001)

    Article  CAS  Google Scholar 

  36. I.T. Paulsen, J. Reizer, R.Z. Jin, E.C. Lin, M.H. Saier, Microbiology 146, 2343 (2000)

    CAS  Google Scholar 

  37. S.H. Huang, Y.H. Chen, G. Kong, S.H. Chen, J. Besemer, M. Borodovsky, A. Jong, Funct Integr Genomics 1, 312 (2001)

    Article  CAS  Google Scholar 

  38. B. Zimmer, A. Hillmann, B. Gorke, FEMS Microbiol Lett 286, 96 (2008)

    Article  CAS  Google Scholar 

  39. B. Anderson, N. Weigel, W. Kundig, S. Roseman, J Biol Chem 246, 7023 (1971)

    CAS  Google Scholar 

  40. N. Weigel, D.A. Powers, S. Roseman, J Biol Chem 257, 14499 (1982)

    CAS  Google Scholar 

  41. W. Kundig, S. Roseman, J Biol Chem 246, 1392 (1971)

    Google Scholar 

  42. P.K. Hammen, E.B. Waygood, R.E. Klevit, Biochemistry 30, 11842 (1991)

    Article  CAS  Google Scholar 

  43. R.E. Klevit, E.B. Waygood, Biochemistry 25, 7774 (1986)

    Article  CAS  Google Scholar 

  44. P.V. Attwood, M.J. Piggott, X.L. Zu, P.G. Besant, Amino Acids 32, 145 (2007)

    Article  CAS  Google Scholar 

  45. P. Rajagopal, E.B. Waygood, R.E. Klevit, Biochemistry 33, 15271 (1994)

    Article  CAS  Google Scholar 

  46. O. Herzberg, R. Klevit, Curr Opin Struct Biol 4, 814 (1994)

    Article  CAS  Google Scholar 

  47. G. Wang, M. Sondej, D.S. Garrett, A. Peterkofsky, G.M. Clore, J Biol Chem 275, 16401 (2000)

    Article  CAS  Google Scholar 

  48. R.H. Geerse, C.R. Ruig, A.R. Schuitema, P.W. Postma, Mol Gen Genet 203, 435 (1986)

    Article  CAS  Google Scholar 

  49. J. Reizer, A. Reizer, M.H. Saier, Microbiology 141, 961 (1995)

    Article  CAS  Google Scholar 

  50. J. Stülke, M. Arnaud, G. Rapoport, I. Martin-Verstraete, Mol Microbiol 28, 865 (1998)

    Article  Google Scholar 

  51. Y.J. Seok, M. Sondej, P. Badawi, M.S. Lewis, M.C. Briggs, H. Jaffe, A. Peterkofsky, J Biol Chem 272, 26511 (1997)

    Article  CAS  Google Scholar 

  52. S. Nessler, Biochim Biophys Acta 1754, 126 (2005)

    Article  CAS  Google Scholar 

  53. S. Nessler, S. Fieulaine, S. Poncet, A. Galinier, J. Deutscher, J. Janin, J Bacteriol 185, 4003 (2003)

    Article  CAS  Google Scholar 

  54. J.A. Marquez, S. Hasenbein, B. Koch, S. Fieulaine, S. Nessler, R.B. Russell, W. Hengstenberg, K. Scheffzek, Proc Natl Acad Sci USA 99, 3458 (2002)

    Article  CAS  Google Scholar 

  55. I. Mijakovic, S. Poncet, A. Galinier, V. Monedero, S. Fieulaine, J. Janin, S. Nessler, J.A. Marquez, K. Scheffzek, S. Hasenbein, W. Hengstenberg, J. Deutscher, Proc Natl Acad Sci USA 99, 13442 (2002)

    Article  CAS  Google Scholar 

  56. A.B. Chang, R. Lin, S.W. Keith, C.V. Tran, M.H. Saier Jr, Mol Membr Biol 21, 171 (2004)

    Article  CAS  Google Scholar 

  57. M.H. Saier Jr, Adv Microb Physiol 40, 81 (1998)

    Article  CAS  Google Scholar 

  58. K.Y. Hu, M.H. Saier Jr, Res Microbiol 153, 405 (2002)

    Article  CAS  Google Scholar 

  59. T.X. Nguyen, M.R. Yen, R.D. Barabote, M.H. Saier Jr, J Mol Microbiol Biotechnol 11, 345 (2006)

    Article  CAS  Google Scholar 

  60. Y. Cao, X. Jin, E.J. Levin, H. Huang, Y. Zong, M. Quick, J. Weng, Y. Pan, J. Love, M. Punta, B. Rost, W.A. Hendrickson, J.A. Javitch, K.R. Rajashankar, M. Zhou, Nature 473, 50 (2011)

    Article  CAS  Google Scholar 

  61. L.A. Kelley, M.J. Sternberg, Nat Protoc 4, 363 (2009)

    Article  CAS  Google Scholar 

  62. B. Erni, B. Zanolari, P. Graff, H.P. Kocher, J Biol Chem 264, 18733 (1989)

    CAS  Google Scholar 

  63. B. Erni, B. Zanolari, H.P. Kocher, J Biol Chem 262, 5238 (1987)

    CAS  Google Scholar 

  64. W. Kundig, S. Roseman, J Biol Chem 246, 1407 (1971)

    CAS  Google Scholar 

  65. B. Erni, H. Trachsel, P.W. Postma, J.P. Rosenbusch, J Biol Chem 257, 13726 (1982)

    CAS  Google Scholar 

  66. G.R. Jacobson, C.A. Lee, M.H. Saier Jr, J Biol Chem 254, 249 (1979)

    CAS  Google Scholar 

  67. C.A. Lee, M.H. Saier Jr, J Biol Chem 258, 10761 (1983)

    CAS  Google Scholar 

  68. G.T. Robillard, J. Broos, Biochim Biophys Acta 1422, 73 (1999)

    Article  CAS  Google Scholar 

  69. U. Waeber, A. Buhr, T. Schunk, B. Erni, FEBS Lett 324, 109 (1993)

    Article  CAS  Google Scholar 

  70. Erni B (2001) In: Winkelmann G (ed) Microbial transport systems. Wiley-VCH, Weinheim, p 115

  71. H.H. Pas, G.T. Robillard, Biochemistry 27, 5835 (1988)

    Article  CAS  Google Scholar 

  72. J. Broos, G.B. Strambini, M. Gonnelli, E.P. Vos, M. Koolhof, G.T. Robillard, Biochemistry 39, 10877 (2000)

    Article  CAS  Google Scholar 

  73. W. Meijberg, G.K. Schuurman-Wolters, G.T. Robillard, Biochemistry 35, 2759 (1996)

    Article  CAS  Google Scholar 

  74. W. Meijberg, G.K. Schuurman-Wolters, G.T. Robillard, J Biol Chem 273, 7949 (1998)

    Article  CAS  Google Scholar 

  75. W. Meijberg, G.K. Schuurman-Wolters, H. Boer, R.M. Scheek, G.T. Robillard, J Biol Chem 273, 20785 (1998)

    Article  CAS  Google Scholar 

  76. B.A. Van Montfort, G.K. Schuurman-Wolters, J. Wind, J. Broos, G.T. Robillard, B. Poolman, J Biol Chem 277, 14717 (2002)

    Article  CAS  Google Scholar 

  77. G. Veldhuis, E. Gabellieri, E.P. Vos, B. Poolman, G.B. Strambini, J. Broos, J Biol Chem 280, 35148 (2005)

    Article  CAS  Google Scholar 

  78. B.A. Van Montfort, G.K. Schuurman-Wolters, R.H. Duurkens, R. Mensen, B. Poolman, G.T. Robillard, J Biol Chem 276, 12756 (2001)

    Article  Google Scholar 

  79. J.S. Lolkema, D.S. Dijkstra, G.T. Robillard, Biochemistry 31, 5514 (1992)

    Article  CAS  Google Scholar 

  80. H.H. Pas, R.H. Hoeve-Duurkens, G.T. Robillard, Biochemistry 27, 5520 (1988)

    Article  CAS  Google Scholar 

  81. M. Opacic, E.P. Vos, B.H. Hesp, J. Broos, J Biol Chem 285, 25324 (2010)

    Article  CAS  Google Scholar 

  82. G. Veldhuis, J. Broos, B. Poolman, R.M. Scheek, Biophys J 89, 201 (2005)

    Article  CAS  Google Scholar 

  83. J.E. Sugiyama, S. Mahmoodian, G.R. Jacobson, Proc Natl Acad Sci USA 88, 9603 (1991)

    Article  CAS  Google Scholar 

  84. R.I. Koning, W. Keegstra, G.T. Oostergetel, G. Schuurman-Wolters, G.T. Robillard, A. Brisson, J Mol Biol 287, 845 (1999)

    Article  CAS  Google Scholar 

  85. D.S. Dijkstra, J. Broos, G.T. Robillard, Anal Biochem 240, 142 (1996)

    Article  CAS  Google Scholar 

  86. E.B. Vervoort, J.B. Bultema, G.K. Schuurman-Wolters, E.R. Geertsma, J. Broos, B. Poolman, J Mol Biol 346, 733 (2005)

    Article  CAS  Google Scholar 

  87. A. Buhr, B. Erni, J Biol Chem 268, 11599 (1993)

    CAS  Google Scholar 

  88. M.H. Saier, M. Yamada, K. Suda, B. Erni, B. Rak, J.S. Lengeler, G. Rapoport, E.B. Waygood, Biochimie 70, 1743 (1988)

    Article  CAS  Google Scholar 

  89. R. Beutler, M. Kaufmann, F. Ruggiero, B. Erni, Biochemistry 39, 3745 (2000)

    Article  CAS  Google Scholar 

  90. R. Beutler, F. Ruggiero, B. Erni, Proc Natl Acad Sci USA 97, 1477 (2000)

    Article  CAS  Google Scholar 

  91. R. Gutknecht, R. Lanz, B. Erni, J Biol Chem 273, 12234 (1998)

    Article  CAS  Google Scholar 

  92. K. Melen, A. Krogh, G. von Heijne, J Mol Biol 327, 735 (2003)

    Article  CAS  Google Scholar 

  93. S. Yagur-Kroll, O. Amster-Choder, J Biol Chem 280, 19306 (2005)

    Article  CAS  Google Scholar 

  94. H. Boer, R.H. Ten Hoeve-Duurkens, G.T. Robillard, Biochemistry 35, 12901 (1996)

    Article  CAS  Google Scholar 

  95. Q.P. Weng, G.R. Jacobson, Biochemistry 32, 11211 (1993)

    Article  CAS  Google Scholar 

  96. Q.P. Weng, J. Elder, G.R. Jacobson, J Biol Chem 267, 19529 (1992)

    CAS  Google Scholar 

  97. R. Lanz, B. Erni, J Biol Chem 273, 12239 (1998)

    Article  CAS  Google Scholar 

  98. A. Buhr, G.A. Daniels, B. Erni, J Biol Chem 267, 3847 (1992)

    CAS  Google Scholar 

  99. G.J.G. Ruijter, G. van Meurs, M.A. Verwey, P.W. Postma, K. Van Dam, J Bacteriol 174, 2843 (1992)

    CAS  Google Scholar 

  100. M.S. Johnson, E.H. Rowsell, B.L. Taylor, FEBS Lett 374, 161 (1995)

    Article  CAS  Google Scholar 

  101. H.L. Kornberg, L.T. Lambourne, A.A. Sproul, Proc Natl Acad Sci USA 97, 1808 (2000)

    Article  CAS  Google Scholar 

  102. H. Oh, Y. Park, C. Park, J Biol Chem 274, 14006 (1999)

    Article  CAS  Google Scholar 

  103. G.S. Begley, K.A. Warner, J.C. Arents, P.W. Postma, G.R. Jacobson, J Bacteriol 178, 940 (1996)

    CAS  Google Scholar 

  104. L. Notley-McRobb, T. Ferenci, J Bacteriol 182, 4437 (2000)

    Article  CAS  Google Scholar 

  105. J. Van der Vlag, P.W. Postma, Mol Gen Genet 248, 236 (1995)

    Article  Google Scholar 

  106. A.P. Vogler, C.P. Broekhuizen, A. Schuitema, J.W. Lengeler, P.W. Postma, Mol Microbiol 2, 719 (1988)

    Article  CAS  Google Scholar 

  107. M. Cai, D.C. Williams Jr, G. Wang, B.R. Lee, A. Peterkofsky, G.M. Clore, J Biol Chem 278, 25191 (2003)

    Article  CAS  Google Scholar 

  108. G. Cornilescu, B.R. Lee, C.C. Cornilescu, G. Wang, A. Peterkofsky, G.M. Clore, J Biol Chem 277, 42289 (2002)

    Article  CAS  Google Scholar 

  109. D.S. Garrett, Y.J. Seok, D.I. Liao, A. Peterkofsky, A.M. Gronenborn, G.M. Clore, Biochemistry 36, 2517 (1997)

    Article  CAS  Google Scholar 

  110. J. Hu, K. Hu, D.C. Williams Jr, M.E. Komlosh, M. Cai, G.M. Clore, J Biol Chem 283, 11024 (2008)

    Article  CAS  Google Scholar 

  111. P.M. Legler, M. Cai, A. Peterkofsky, G.M. Clore, J Biol Chem 279, 39115 (2004)

    Article  CAS  Google Scholar 

  112. A. Peterkofsky, G. Wang, D.S. Garrett, B.R. Lee, Y.J. Seok, G.M. Clore, J Mol Microbiol Biotechnol 3, 347 (2001)

    CAS  Google Scholar 

  113. J.Y. Suh, M. Cai, D.C. Williams Jr, G.M. Clore, J Biol Chem 281, 8939 (2006)

    Article  CAS  Google Scholar 

  114. D.C. Williams Jr, M. Cai, J.Y. Suh, A. Peterkofsky, G.M. Clore, J Biol Chem 280, 20775 (2005)

    Article  CAS  Google Scholar 

  115. J.H. Hurley, H.R. Faber, D. Worthylake, N.D. Meadow, S. Roseman, D.W. Pettigrew, S.J. Remington, Science 259, 673 (1993)

    Article  CAS  Google Scholar 

  116. T.W. Nam, H.I. Jung, Y.J. An, Y.H. Park, S.H. Lee, Y.J. Seok, S.S. Cha, Proc Natl Acad Sci USA 105, 3751 (2008)

    Article  CAS  Google Scholar 

  117. A. Zurbriggen, J.M. Jeckelmann, S. Christen, C. Bieniossek, U. Baumann, B. Erni, J Biol Chem 283, 35789 (2008)

    Article  CAS  Google Scholar 

  118. M.M. McEvoy, F.W. Dahlquist, Curr Opin Struct Biol 7, 793 (1997)

    Article  CAS  Google Scholar 

  119. R.L.M. Van Montfort, T. Pijning, K.H. Kalk, J. Reizer, M.H. Saier, M.M.G.M. Thunnissen, G.T. Robillard, B.W. Dijkstra, Structure 5, 217 (1997)

    Article  Google Scholar 

  120. I.M. Nooren, J.M. Thornton, J Mol Biol 325, 991 (2003)

    Article  CAS  Google Scholar 

  121. D.S. Garrett, Y.J. Seok, A. Peterkofsky, G.M. Clore, A.M. Gronenborn, Protein Sci 7, 789 (1998)

    Article  CAS  Google Scholar 

  122. J.G. Pelton, D.A. Torchia, N.D. Meadow, S. Roseman, Protein Sci 2, 543 (1993)

    Article  CAS  Google Scholar 

  123. A.A. Van Dijk, L.C. de Lange, W.W. Bachovchin, G.T. Robillard, Biochemistry 29, 8164 (1990)

    Article  Google Scholar 

  124. A.A. Van Dijk, R.M. Scheek, K. Dijkstra, G.K. Wolters, G.T. Robillard, Biochemistry 31, 9063 (1992)

    Article  Google Scholar 

  125. M. Meins, P. Jeno, D. Muller, W.J. Richter, J.P. Rosenbusch, B. Erni, J Biol Chem 268, 11604 (1993)

    CAS  Google Scholar 

  126. M. Eberstadt, S.G. Grdadolnik, G. Gemmecker, H. Kessler, A. Buhr, B. Erni, Biochemistry 35, 11286 (1996)

    Article  CAS  Google Scholar 

  127. G. Gemmecker, M. Eberstadt, A. Buhr, R. Lanz, S.G. Grdadolnik, H. Kessler, B. Erni, Biochemistry 36, 7408 (1997)

    Article  CAS  Google Scholar 

  128. G.S. Begley, D.E. Hansen, G.R. Jacobson, J.R. Knowles, Biochemistry 21, 5552 (1982)

    Article  CAS  Google Scholar 

  129. E.G. Mueller, S.S. Khandekar, J.R. Knowles, G.R. Jacobson, Biochemistry 29, 6892 (1990)

    Article  CAS  Google Scholar 

  130. C. Jardin, A.H. Horn, G. Schurer, H. Sticht, J Phys Chem B 112, 13391 (2008)

    Article  CAS  Google Scholar 

  131. R.L.M. Van Montfort, T. Pijning, K.H. Kalk, I. Hangyi, M.L.C.E. Kouwijzer, G.T. Robillard, B.W. Dijkstra, Structure 6, 377 (1998)

    Article  Google Scholar 

  132. N.K. Williams, E. Liepinsh, S.J. Watt, P. Prosselkov, J.M. Matthews, P. Attard, J.L. Beck, N.E. Dixon, G. Otting, J Mol Biol 346, 1095 (2005)

    Article  CAS  Google Scholar 

  133. J.Y. Suh, J. Iwahara, G.M. Clore, Proc Natl Acad Sci USA 104, 3153 (2007)

    Article  CAS  Google Scholar 

  134. S.J. Curtis, W. Epstein, J Bacteriol 122, 1189 (1975)

    CAS  Google Scholar 

  135. C.L. Bouma, S. Roseman, J Biol Chem 271, 33468 (1996)

    Article  CAS  Google Scholar 

  136. B. Erni, B. Zanolari, J Biol Chem 260, 15495 (1985)

    CAS  Google Scholar 

  137. N. Williams, D.K. Fox, C. Shea, S. Roseman, Proc Natl Acad Sci USA 83, 8934 (1986)

    Article  CAS  Google Scholar 

  138. F. Huber, B. Erni, Eur J Biochem 239, 810 (1996)

    Article  CAS  Google Scholar 

  139. Y. Shi, Y.X. Li, Y.Y. Li, BMC Bioinformatics 11(Suppl 11), S9 (2010)

    Article  Google Scholar 

  140. R. Gutknecht, K. Flükiger, R. Lanz, B. Erni, J Biol Chem 274, 6091 (1999)

    Article  CAS  Google Scholar 

  141. B. Stolz, M. Huber, Z. Markovic-Housley, B. Erni, J Biol Chem 268, 27094 (1993)

    CAS  Google Scholar 

  142. R.S. Nunn, Z. Markovic-Housley, J.C. Génovésio-Taverne, K. Flükiger, P.J. Rizkallah, J.N. Jansonius, T. Schirmer, B. Erni, J Mol Biol 259, 502 (1996)

    Article  CAS  Google Scholar 

  143. G.L. Orriss, B. Erni, T. Schirmer, J Mol Biol 327, 1111 (2003)

    Article  CAS  Google Scholar 

  144. S. Schauder, R.S. Nunn, R. Lanz, B. Erni, T. Schirmer, J Mol Biol 276, 591 (1998)

    Article  CAS  Google Scholar 

  145. B. Erni, C. Siebold, S. Christen, A. Srinivas, A. Oberholzer, U. Baumann, Cell Mol Life Sci 63, 890 (2006)

    Article  CAS  Google Scholar 

  146. L.N. Kinch, S. Cheek, N.V. Grishin, Protein Sci 14, 360 (2005)

    Article  CAS  Google Scholar 

  147. C. Siebold, L.F. Garcia-Alles, B. Erni, U. Baumann, Proc Natl Acad Sci USA 100, 8188 (2003)

    Article  CAS  Google Scholar 

  148. Q. Mao, T. Schunk, K. Flükiger, B. Erni, J Biol Chem 270, 5258 (1995)

    Article  CAS  Google Scholar 

  149. L.F. Garcia-Alles, A. Zahn, B. Erni, Biochemistry 41, 10077 (2002)

    Article  CAS  Google Scholar 

  150. J. Elliott, W. Arber, Mol Gen Genet 161, 1 (1978)

    Article  CAS  Google Scholar 

  151. N.D. Maynard, E.W. Birch, J.C. Sanghvi, L. Chen, M.V. Gutschow, M.W. Covert, PLoS Genet 6, e1001017 (2010)

    Article  CAS  Google Scholar 

  152. P.A. Gurnev, A.B. Oppenheim, M. Winterhalter, S.M. Bezrukov, J Mol Biol 359, 1447 (2006)

    Article  CAS  Google Scholar 

  153. S.W. Emmons, V. MacCosham, R.L. Baldwin, J Mol Biol 91, 133 (1975)

    Article  CAS  Google Scholar 

  154. Katsura I (1983) In: Hendrix RW (ed) Lambda II. Cold Spring Harbor Laboratory, New York, p 331

  155. C.A. Roessner, G.M. Ihler, J Bacteriol 157, 165 (1984)

    CAS  Google Scholar 

  156. D. Scandella, W. Arber, Virology 69, 206 (1976)

    Article  CAS  Google Scholar 

  157. M. Esquinas-Rychen, B. Erni, J Mol Microbiol Biotechnol 3, 361 (2001)

    CAS  Google Scholar 

  158. M. Hassan, M. Kjos, I.F. Nes, D.B. Diep, F. Lotfipour, J Appl Microbiol 113, 723 (2012)

    Article  CAS  Google Scholar 

  159. E. Strahsburger, M. Baeza, O. Monasterio, R. Lagos, Antimicrob Agents Chemother 49, 3083 (2005)

    Article  CAS  Google Scholar 

  160. Y. Hechard, C. Pelletier, Y. Cenatiempo, J. Frere, Microbiology 147, 1575 (2001)

    CAS  Google Scholar 

  161. M. Ramnath, M. Beukes, K. Tamura, J.W. Hastings, Appl Environ Microbiol 66, 3098 (2000)

    Article  CAS  Google Scholar 

  162. E. Rodriguez, M. Lavina, Antimicrob Agents Chemother 47, 181 (2003)

    Article  CAS  Google Scholar 

  163. F. Gerard, N. Pradel, L.F. Wu, J Bacteriol 187, 1945 (2005)

    Article  CAS  Google Scholar 

  164. C. Gabrielsen, D.A. Brede, P.E. Hernandez, I.F. Nes, D.B. Diep, Antimicrob Agents Chemother 56, 2908 (2012)

    Article  CAS  Google Scholar 

  165. S. Bieler, F. Silva, C. Soto, D. Belin, J Bacteriol 188, 7049 (2006)

    Article  CAS  Google Scholar 

  166. S. Bieler, F. Silva, D. Belin, Res Microbiol 161, 706 (2010)

    Article  CAS  Google Scholar 

  167. S.I. Patzer, M.R. Baquero, D. Bravo, F. Moreno, K. Hantke, Microbiology 149, 2557 (2003)

    Article  CAS  Google Scholar 

  168. D.B. Diep, M. Skaugen, Z. Salehian, H. Holo, I.F. Nes, Proc Natl Acad Sci USA 104, 2384 (2007)

    Article  CAS  Google Scholar 

  169. M. Kjos, I.F. Nes, D.B. Diep, Appl Environ Microbiol 77, 3335 (2011)

    Article  CAS  Google Scholar 

  170. J. Nissen-Meyer, C. Oppegard, P. Rogne, H.S. Haugen, P.E. Kristiansen, Probiotics Antimicrob Proteins 2, 52 (2010)

    Article  CAS  Google Scholar 

  171. M. Kjos, I.F. Nes, D.B. Diep, Microbiology 155, 2949 (2009)

    Article  CAS  Google Scholar 

  172. M. Kjos, Z. Salehian, I.F. Nes, D.B. Diep, J Bacteriol 192, 5906 (2010)

    Article  CAS  Google Scholar 

  173. R.Z. Jin, E.C.C. Lin, J Gen Microbiol 130, 83 (1984)

    CAS  Google Scholar 

  174. F.R. Blattner, G. Plunkett III, C.A. Bloch, N.T. Perna, V. Burland, M. Riley, J. Collado-Vides, J.D. Glasner, C.K. Rode, G.F. Mayhew, J. Gregor, N.W. Davis, H.A. Kirkpatrick, M.A. Goeden, D.J. Rose, B. Mau, Y. Shao, Science 277, 1453 (1997)

    Article  CAS  Google Scholar 

  175. R. Daniel, K. Stuertz, G. Gottschalk, J Bacteriol 177, 4392 (1995)

    CAS  Google Scholar 

  176. A.E. Oberholzer, P. Schneider, U. Baumann, B. Erni, J Mol Biol 359, 539 (2006)

    Article  CAS  Google Scholar 

  177. C. Siebold, I. Arnold, L.F. Garcia-Alles, U. Baumann, B. Erni, J Biol Chem 278, 48236 (2003)

    Article  CAS  Google Scholar 

  178. C. Bachler, K. Flukiger-Bruhwiler, P. Schneider, P. Bahler, B. Erni, J Biol Chem 280, 18321 (2005)

    Article  CAS  Google Scholar 

  179. L.F. Garcia-Alles, C. Siebold, T.L. Nyffeler, K. Flukiger-Bruhwiler, P. Schneider, H.B. Burgi, U. Baumann, B. Erni, Biochemistry 43, 13037 (2004)

    Article  CAS  Google Scholar 

  180. A.N. Lupas, J. Martin, Curr Opin Struct Biol 12, 746 (2002)

    Article  CAS  Google Scholar 

  181. J. Schumacher, N. Joly, M. Rappas, X. Zhang, M. Buck, J Struct Biol 156, 190 (2006)

    Article  CAS  Google Scholar 

  182. C. Bachler, P. Schneider, P. Bahler, A. Lustig, B. Erni, EMBO J 24, 283 (2005)

    Article  CAS  Google Scholar 

  183. M. Molin, J. Norbeck, A. Blomberg, J Biol Chem 278, 1415 (2003)

    Article  CAS  Google Scholar 

  184. N. Akhtar, A. Blomberg, L. Adler, FEBS Lett 403, 173 (1997)

    Article  CAS  Google Scholar 

  185. J. Norbeck, A. Blomberg, J Biol Chem 272, 5544 (1997)

    Article  CAS  Google Scholar 

  186. S. Christen, A. Srinivas, P. Bahler, A. Zeller, D. Pridmore, C. Bieniossek, U. Baumann, B. Erni, J Biol Chem 281, 23129 (2006)

    Article  CAS  Google Scholar 

  187. B.M. Hogema, J.C. Arents, R. Bader, K. Eijkemans, H. Yoshida, H. Takahashi, H. Alba, P.W. Postma, Mol Microbiol 30, 487 (1998)

    Article  CAS  Google Scholar 

  188. A. Kremling, K. Bettenbrock, E.D. Gilles, Bioinformatics 24, 704 (2008)

    Article  CAS  Google Scholar 

  189. K. Bettenbrock, T. Sauter, K. Jahreis, A. Kremling, J.W. Lengeler, E.D. Gilles, J Bacteriol 189, 6891 (2007)

    Article  CAS  Google Scholar 

  190. A. Kremling, K. Bettenbrock, E.D. Gilles, BMC Syst Biol 1, 42 (2007)

    Article  CAS  Google Scholar 

  191. N.D. Meadow, R.L. Mattoo, R.S. Savtchenko, S. Roseman, Biochemistry 44, 12790 (2005)

    Article  CAS  Google Scholar 

  192. N.D. Meadow, R.S. Savtchenko, A. Nezami, S. Roseman, J Biol Chem 280, 41872 (2005)

    Article  CAS  Google Scholar 

  193. J.M. Rohwer, N.D. Meadow, S. Roseman, H.V. Westerhoff, P.W. Postma, J Biol Chem 275, 34909 (2000)

    Article  CAS  Google Scholar 

  194. J.M. Gancedo, Microbiol Mol Biol Rev 62, 334 (1998)

    CAS  Google Scholar 

  195. M. Liu, T. Durfee, J.E. Cabrera, K. Zhao, D.J. Jin, F.R. Blattner, J Biol Chem 280, 15921 (2005)

    Article  CAS  Google Scholar 

  196. U. Lendenmann, T. Egli, Microbiology 141, 71 (1995)

    Article  CAS  Google Scholar 

  197. D.W. Pettigrew, N.D. Meadow, S. Roseman, S.J. Remington, Biochemistry 37, 4875 (1998)

    Article  CAS  Google Scholar 

  198. M. Kuroda, N. Osaki, M. Tsuda, T. Tsuchiya, Chem Pharm Bull (Tokyo) 40, 1637 (1992)

    Article  CAS  Google Scholar 

  199. M. Kuroda, S. de Waard, K. Mizushima, M. Tsuda, P. Postma, T. Tsuchiya, J Biol Chem 267, 18336 (1992)

    CAS  Google Scholar 

  200. M. Sondej, A.B. Weinglass, A. Peterkofsky, H.R. Kaback, Biochemistry 41, 5556 (2002)

    Article  CAS  Google Scholar 

  201. M. Sondej, J.L. Vazquez-Ibar, A. Farshidi, A. Peterkofsky, H.R. Kaback, Biochemistry 42, 9153 (2003)

    Article  CAS  Google Scholar 

  202. A. Stein, M. Seifert, R. Volkmer-Engert, J. Siepelmeyer, K. Jahreis, E. Schneider, Eur J Biochem 269, 4074 (2002)

    Article  CAS  Google Scholar 

  203. J. Van der Vlag, R. Van’t Hof, K. Van Dam, P.W. Postma, Eur J Biochem 230, 170 (1995)

    Article  Google Scholar 

  204. V.N. Gershanovitch, N.V. Yourovitskaya, L.V. Komissarova, T.N. Bolshakova, R.S. Erlagaeva, G.I. Bourd, Mol Gen Genet 140, 81 (1975)

    Article  CAS  Google Scholar 

  205. M.C. Jones-Mortimer, H.L. Kornberg, FEBS Lett 48, 93 (1974)

    Article  CAS  Google Scholar 

  206. M.H. Saier, S. Roseman, J Biol Chem 247, 972 (1972)

    CAS  Google Scholar 

  207. B.J. Scholte, P.W. Postma, J Bacteriol 141, 751 (1980)

    CAS  Google Scholar 

  208. M. de Boer, C.P. Broekhuizen, P.W. Postma, J Bacteriol 167, 393 (1986)

    Google Scholar 

  209. S.O. Nelson, P.W. Postma, Eur J Biochem 139, 29 (1984)

    Article  CAS  Google Scholar 

  210. S.O. Nelson, J.K. Wright, P.W. Postma, EMBO J 2, 715 (1983)

    CAS  Google Scholar 

  211. T. Osumi, M.H. Saier Jr, Ann Microbiol (Paris) 133, 269 (1982)

    CAS  Google Scholar 

  212. T. Osumi, M.H. Saier Jr, Proc Natl Acad Sci USA 79, 1457 (1982)

    Article  CAS  Google Scholar 

  213. M. Feese, D.W. Pettigrew, N.D. Meadow, S. Roseman, S.J. Remington, Proc Natl Acad Sci USA 91, 3544 (1994)

    Article  CAS  Google Scholar 

  214. M.D. Feese, L. Comolli, N.D. Meadow, S. Roseman, S.J. Remington, Biochemistry 36, 16087 (1997)

    Article  CAS  Google Scholar 

  215. E. Krin, O. Sismeiro, A. Danchin, P.N. Bertin, Microbiology 148, 1553 (2002)

    CAS  Google Scholar 

  216. L. Notley-McRobb, A. Death, T. Ferenci, Microbiology 143(Pt 6), 1909 (1997)

    Article  CAS  Google Scholar 

  217. P. Reddy, M. Kamireddi, J Bacteriol 180, 732 (1998)

    CAS  Google Scholar 

  218. J.U. Linder, Biochem J 415, 449 (2008)

    Article  CAS  Google Scholar 

  219. Y.H. Park, B.R. Lee, Y.J. Seok, A. Peterkofsky, J Biol Chem 281, 6448 (2006)

    Article  CAS  Google Scholar 

  220. P. Reddy, J. Hoskins, K. McKenney, Anal Biochem 231, 282 (1995)

    Article  CAS  Google Scholar 

  221. H. Sharma, S. Yu, J. Kong, J. Wang, T.A. Steitz, Proc Natl Acad Sci USA 106, 16604 (2009)

    Article  CAS  Google Scholar 

  222. H. de Reuse, A. Kolb, A. Danchin, J Mol Biol 226, 623 (1992)

    Article  Google Scholar 

  223. H. de Reuse, A. Danchin, J Bacteriol 170, 3827 (1988)

    Google Scholar 

  224. K. Kimata, T. Inada, H. Tagami, H. Aiba, Mol Microbiol 29, 1509 (1998)

    Article  CAS  Google Scholar 

  225. K. Kimata, H. Takahashi, T. Inada, P. Postma, H. Aiba, Proc Natl Acad Sci USA 94, 12914 (1997)

    Article  CAS  Google Scholar 

  226. J. Plumbridge, Mol Microbiol 33, 260 (1999)

    Article  CAS  Google Scholar 

  227. A.W. Rephaeli, M.H. Saier, J Bacteriol 141, 658 (1980)

    CAS  Google Scholar 

  228. S. Seeto, L. Notley-McRobb, T. Ferenci, Res Microbiol 155, 211 (2004)

    Article  CAS  Google Scholar 

  229. D. Shin, S. Lim, Y.J. Seok, S. Ryu, J Biol Chem 276, 25871 (2001)

    Article  CAS  Google Scholar 

  230. Y. Tanaka, K. Kimata, T. Inada, H. Tagami, H. Aiba, Genes Cells 4, 391 (1999)

    Article  CAS  Google Scholar 

  231. H. Aiba, M. Kawamukai, A. Ishihama, Nucleic Acids Res 11, 3451 (1983)

    Article  CAS  Google Scholar 

  232. T. Inada, H. Takahashi, T. Mizuno, H. Aiba, Mol Gen Genet 253, 198 (1996)

    Article  CAS  Google Scholar 

  233. M. Kawamukai, J. Kishimoto, R. Utsumi, M. Himeno, T. Komano, H. Aiba, J Bacteriol 164, 872 (1985)

    CAS  Google Scholar 

  234. K. Mori, H. Aiba, J Biol Chem 260, 14838 (1985)

    CAS  Google Scholar 

  235. A. Hanamura, H. Aiba, Mol Microbiol 6, 2489 (1992)

    Article  CAS  Google Scholar 

  236. A. Hanamura, H. Aiba, Nucleic Acids Res 19, 4413 (1991)

    Article  CAS  Google Scholar 

  237. T. Shimada, N. Fujita, K. Yamamoto, A. Ishihama, PLoS ONE 6, e20081 (2011)

    Article  CAS  Google Scholar 

  238. O. Resendis-Antonio, J.A. Freyre-Gonzalez, R. Menchaca-Mendez, R.M. Gutierrez-Rios, A. Martinez-Antonio, C. Avila-Sanchez, J. Collado-Vides, Trends Genet 21, 16 (2005)

    Article  CAS  Google Scholar 

  239. T.F. Cooper, S.K. Remold, R.E. Lenski, D. Schneider, PLoS Genet 4, e35 (2008)

    Article  CAS  Google Scholar 

  240. G. Gosset, Z. Zhang, S. Nayyar, W.A. Cuevas, M.H. Saier Jr, J Bacteriol 186, 3516 (2004)

    Article  CAS  Google Scholar 

  241. K. Hollands, S.J. Busby, G.S. Lloyd, FEMS Microbiol Lett 274, 89 (2007)

    Article  CAS  Google Scholar 

  242. D. Thieffry, A.M. Huerta, E. Perez-Rueda, J. Collado-Vides, BioEssays 20, 433 (1998)

    Article  CAS  Google Scholar 

  243. D. Thieffry, H. Salgado, A.M. Huerta, J. Collado-Vides, Bioinformatics 14, 391 (1998)

    Article  CAS  Google Scholar 

  244. G. Gonzalez-Gil, R. Kahmann, G. Muskhelishvili, EMBO J 17, 2877 (1998)

    Article  CAS  Google Scholar 

  245. W. Nasser, R. Schneider, A. Travers, G. Muskhelishvili, J Biol Chem 276, 17878 (2001)

    Article  CAS  Google Scholar 

  246. Y. Nishio, Y. Usuda, K. Matsui, H. Kurata, Mol Syst Biol 4, 160 (2008)

    Article  CAS  Google Scholar 

  247. N. Amin, A. Peterkofsky, J Biol Chem 270, 11803 (1995)

    Article  CAS  Google Scholar 

  248. R. Imamura, K. Yamanaka, T. Ogura, S. Hiraga, N. Fujita, A. Ishihama, H. Niki, J Biol Chem 271, 25423 (1996)

    Article  CAS  Google Scholar 

  249. Y. Sasakura, T. Yoshimura-Suzuki, H. Kurokawa, T. Shimizu, Acc Chem Res 39, 37 (2006)

    Article  CAS  Google Scholar 

  250. T. Yoshimura-Suzuki, I. Sagami, N. Yokota, H. Kurokawa, T. Shimizu, J Bacteriol 187, 6678 (2005)

    Article  CAS  Google Scholar 

  251. T. Eppler, W. Boos, Mol Microbiol 33, 1221 (1999)

    Article  CAS  Google Scholar 

  252. T. Eppler, P. Postma, A. Schutz, U. Volker, W. Boos, J Bacteriol 184, 3044 (2002)

    Article  CAS  Google Scholar 

  253. B.M. Hogema, J.C. Arents, T. Inada, H. Aiba, K. Van Dam, P.W. Postma, Mol Microbiol 24, 857 (1997)

    Article  CAS  Google Scholar 

  254. A. Iwamoto, S. Lemire, T. Yonesaki, Mol Microbiol 70, 1570 (2008)

    Article  CAS  Google Scholar 

  255. A. Nanchen, A. Schicker, O. Revelles, U. Sauer, J Bacteriol 190, 2323 (2008)

    Article  CAS  Google Scholar 

  256. Y.J. Seok, B.M. Koo, M. Sondej, A. Peterkofsky, J Mol Microbiol Biotechnol 3, 385 (2001)

    CAS  Google Scholar 

  257. R.A. Roehl, R.T. Vinopal, J Bacteriol 142, 120 (1980)

    CAS  Google Scholar 

  258. K. Hosono, H. Kakuda, S. Ichihara, Biosci Biotechnol Biochem 59, 256 (1995)

    Article  CAS  Google Scholar 

  259. A. Negrete, N. Majdalani, J.N. Phue, J. Shiloach, Nature Biotechnol. 2011)

  260. J.Y. Jeong, Y.J. Kim, N. Cho, D. Shin, T.W. Nam, S. Ryu, Y.J. Seok, J Biol Chem 279, 38513 (2004)

    Article  CAS  Google Scholar 

  261. S.J. Lee, W. Boos, J.P. Bouche, J. Plumbridge, EMBO J 19, 5353 (2000)

    Article  CAS  Google Scholar 

  262. J. Plumbridge, Mol Microbiol 29, 1053 (1998)

    Article  CAS  Google Scholar 

  263. J. Plumbridge, Mol Microbiol 27, 369 (1998)

    Article  CAS  Google Scholar 

  264. J. Plumbridge, Curr Opin Microbiol 5, 187 (2002)

    Article  CAS  Google Scholar 

  265. S. Seitz, S.J. Lee, C. Pennetier, W. Boos, J. Plumbridge, J Biol Chem 278, 10744 (2003)

    Article  CAS  Google Scholar 

  266. Y. Tanaka, K. Kimata, H. Aiba, EMBO J 19, 5344 (2000)

    Article  CAS  Google Scholar 

  267. Y. Tanaka, F. Itoh, K. Kimata, H. Aiba, Mol Microbiol 53, 941 (2004)

    Article  CAS  Google Scholar 

  268. T.W. Nam, S.H. Cho, D. Shin, J.H. Kim, J.Y. Jeong, J.H. Lee, J.H. Roe, A. Peterkofsky, S.O. Kang, S. Ryu, Y.J. Seok, EMBO J 20, 491 (2001)

    Article  CAS  Google Scholar 

  269. S.Y. Kim, T.W. Nam, D. Shin, B.M. Koo, Y.J. Seok, S. Ryu, J Biol Chem 274, 25398 (1999)

    Article  CAS  Google Scholar 

  270. T. Zeppenfeld, C. Larisch, J.W. Lengeler, K. Jahreis, J Bacteriol 182, 4443 (2000)

    Article  CAS  Google Scholar 

  271. A.K. Becker, T. Zeppenfeld, A. Staab, S. Seitz, W. Boos, T. Morita, H. Aiba, K. Mahr, F. Titgemeyer, K. Jahreis, J Bacteriol 188, 5439 (2006)

    Article  CAS  Google Scholar 

  272. M.S. Conejo, S.M. Thompson, B.G. Miller, J Mol Evol 70, 545 (2010)

    Article  CAS  Google Scholar 

  273. J. Oberto, BMC Bioinformatics 11, 554 (2010)

    Article  CAS  Google Scholar 

  274. T. Miyashiro, W. Klein, D. Oehlert, X. Cao, J. Schwartzman, E.G. Ruby, Mol Microbiol 82, 894 (2011)

    Google Scholar 

  275. C. Pennetier, L. Dominguez-Ramirez, J. Plumbridge, Mol Microbiol 67, 364 (2008)

    Article  CAS  Google Scholar 

  276. H. Aiba, Curr Opin Microbiol 10, 134 (2007)

    Article  CAS  Google Scholar 

  277. C.K. Vanderpool, Curr Opin Microbiol 10, 146 (2007)

    Article  CAS  Google Scholar 

  278. K. Kimata, Y. Tanaka, T. Inada, H. Aiba, EMBO J 20, 3587 (2001)

    Article  CAS  Google Scholar 

  279. J.B. Rice, C.K. Vanderpool, Nucleic Acids Res 39, 3806 (2011)

    Article  CAS  Google Scholar 

  280. H. Kawamoto, Y. Koide, T. Morita, H. Aiba, Mol Microbiol 61, 1013 (2006)

    Article  CAS  Google Scholar 

  281. T. Morita, Y. Mochizuki, H. Aiba, Proc Natl Acad Sci USA 103, 4858 (2006)

    Article  CAS  Google Scholar 

  282. K. Maki, K. Uno, T. Morita, H. Aiba, Proc Natl Acad Sci USA 105, 10332 (2008)

    Article  CAS  Google Scholar 

  283. H. Kawamoto, T. Morita, A. Shimizu, T. Inada, H. Aiba, Genes Dev 19, 328 (2005)

    Article  CAS  Google Scholar 

  284. C.K. Vanderpool, S. Gottesman, Nat Struct Mol Biol 12, 285 (2005)

    Article  CAS  Google Scholar 

  285. C.S. Wadler, C.K. Vanderpool, Proc Natl Acad Sci USA 104, 20454 (2007)

    Article  CAS  Google Scholar 

  286. C.K. Vanderpool, S. Gottesman, Mol Microbiol 54, 1076 (2004)

    Article  CAS  Google Scholar 

  287. C.K. Vanderpool, S. Gottesman, J Bacteriol 189, 2238 (2007)

    Article  CAS  Google Scholar 

  288. T. Morita, K. Maki, H. Aiba, Genes Dev 19, 2176 (2005)

    Article  CAS  Google Scholar 

  289. H. Van Tilbeurgh, N. Declerck, Curr Opin Struct Biol 11, 685 (2001)

    Article  Google Scholar 

  290. O. Amster-Choder, Curr Opin Microbiol 8, 127 (2005)

    Article  CAS  Google Scholar 

  291. B. Gorke, J Biol Chem 278, 46219 (2003)

    Article  CAS  Google Scholar 

  292. B. Görke, B. Rak, EMBO J 18, 3370 (1999)

    Article  Google Scholar 

  293. N. Declerck, N.L. Minh, Y. Yang, V. Bloch, M. Kochoyan, S. Aymerich, J Mol Biol 319, 1035 (2002)

    Article  CAS  Google Scholar 

  294. M. Graille, C.Z. Zhou, V. Receveur-Brechot, B. Collinet, N. Declerck, H. Van Tilbeurgh, J Biol Chem 280, 14780 (2005)

    Article  CAS  Google Scholar 

  295. H. Van Tilbeurgh, D. Le Coq, N. Declerck, EMBO J 20, 3789 (2001)

    Article  Google Scholar 

  296. Y. Yang, N. Declerck, X. Manival, S. Aymerich, M. Kochoyan, EMBO J 21, 1987 (2002)

    Article  CAS  Google Scholar 

  297. H. Demene, T. Ducat, K. De Guillen, C. Birck, S. Aymerich, M. Kochoyan, N. Declerck, J Biol Chem 283, 30838 (2008)

    Article  CAS  Google Scholar 

  298. S. Dole, V. Nagarajavel, K. Schnetz, Mol Microbiol 52, 589 (2004)

    Article  CAS  Google Scholar 

  299. T.S. Sankar, G. Neelakanta, V. Sangal, G. Plum, M. Achtman, K. Schnetz, PLoS Genet 5, e1000405 (2009)

    Article  CAS  Google Scholar 

  300. K. Schnetz, EMBO J 14, 2545 (1995)

    CAS  Google Scholar 

  301. M. Giel, M. Desnoyer, J. Lopilato, Genetics 143, 627 (1996)

    CAS  Google Scholar 

  302. G.R. Venkatesh, F.C. Kembou Koungni, A. Paukner, T. Stratmann, B. Blissenbach, K. Schnetz, J Bacteriol 192, 6456 (2010)

    Article  CAS  Google Scholar 

  303. C.J. Dorman, Nat Rev Microbiol 5, 157 (2007)

    Article  CAS  Google Scholar 

  304. O. Amster-Choder, F. Houman, A. Wright, Cell 58, 847 (1989)

    Article  CAS  Google Scholar 

  305. O. Amster-Choder, A. Wright, Science 249, 540 (1990)

    Article  CAS  Google Scholar 

  306. K. Schnetz, B. Rak, Proc Natl Acad Sci USA 87, 5074 (1990)

    Article  CAS  Google Scholar 

  307. K. Schnetz, B. Rak, EMBO J 7, 3271 (1988)

    CAS  Google Scholar 

  308. F.M. Rothe, T. Bahr, J. Stulke, B. Rak, B. Gorke, Proc Natl Acad Sci USA 109, 15906 (2012)

    Article  CAS  Google Scholar 

  309. B. Gorke, J. Stulke, Nat Rev Microbiol 6, 613 (2008)

    Article  CAS  Google Scholar 

  310. M.H. Schmalisch, S. Bachem, J. Stulke, J Biol Chem 278, 51108 (2003)

    Article  CAS  Google Scholar 

  311. E. Ben Zeev, L. Fux, O. Amster-Choder, M. Eisenstein, J Mol Biol 347, 693 (2005)

    Article  CAS  Google Scholar 

  312. Q. Chen, H. Engelberg-Kulka, O. Amster-Choder, J Biol Chem 272, 17263 (1997)

    Article  CAS  Google Scholar 

  313. B. Gorke, B. Rak, J Mol Biol 308, 131 (2001)

    Article  CAS  Google Scholar 

  314. H. Raveh, L. Lopian, A. Nussbaum-Shochat, A. Wright, O. Amster-Choder, Proc Natl Acad Sci USA 106, 13523 (2009)

    Article  CAS  Google Scholar 

  315. P. Tortosa, N. Declerck, H. Dutartre, C. Lindner, J. Deutscher, D. Le Coq, Mol Microbiol 41, 1381 (2001)

    Article  CAS  Google Scholar 

  316. S.A. Henstra, R.H. Duurkens, G.T. Robillard, J Biol Chem 275, 7037 (2000)

    Article  CAS  Google Scholar 

  317. I. Martin-Verstraete, V. Charrier, J. Stülke, A. Galinier, B. Erni, G. Rapoport, J. Deutscher, Mol Microbiol 28, 293 (1998)

    Article  CAS  Google Scholar 

  318. D.B. Greenberg, J. Stulke, M.H. Saier Jr, Res Microbiol 153, 519 (2002)

    Article  CAS  Google Scholar 

  319. P. Joyet, M. Derkaoui, S. Poncet, J. Deutscher, Mol Microbiol 76, 1279 (2010)

    Article  CAS  Google Scholar 

  320. M.J. Merrick, J.R. Coppard, Mol Microbiol 3, 1765 (1989)

    Article  CAS  Google Scholar 

  321. K. Pfluger-Grau, B. Gorke, Trends Microbiol 18, 205 (2010)

    Article  CAS  Google Scholar 

  322. B.S. Powell, D.L. Court, T. Inada, Y. Nakamura, V. Michotey, X. Cui, A. Reizer, M.H. Saier, J. Reizer, J Biol Chem 270, 4822 (1995)

    Article  CAS  Google Scholar 

  323. C.R. Lee, B.M. Koo, S.H. Cho, Y.J. Kim, M.J. Yoon, A. Peterkofsky, Y.J. Seok, Mol Microbiol 58, 334 (2005)

    Article  CAS  Google Scholar 

  324. C.R. Lee, S.H. Cho, M.J. Yoon, A. Peterkofsky, Y.J. Seok, Proc Natl Acad Sci USA 104, 4124 (2007)

    Article  CAS  Google Scholar 

  325. K. Pfluger-Grau, M. Chavarria, V. de Lorenzo, Biochim Biophys Acta 1810, 995 (2011)

    Article  CAS  Google Scholar 

  326. N.D. King, M.R. O’Brian, J Biol Chem 276, 21311 (2001)

    Article  CAS  Google Scholar 

  327. A. Kouzuma, T. Endoh, T. Omori, H. Nojiri, H. Yamane, H. Habe, FEMS Microbiol Lett 275, 175 (2007)

    Article  CAS  Google Scholar 

  328. O.V. Mavrodi, D.V. Mavrodi, D.M. Weller, L.S. Thomashow, Appl Environ Microbiol 72, 7111 (2006)

    Article  CAS  Google Scholar 

  329. R. Noguez, D. Segura, S. Moreno, A. Hernandez, K. Juarez, G. Espin, J Mol Microbiol Biotechnol 15, 244 (2008)

    Article  CAS  Google Scholar 

  330. F. Velazquez, K. Pfluger, I. Cases, L.I. De Eugenio, V. de Lorenzo, J Bacteriol 189, 4529 (2007)

    Article  CAS  Google Scholar 

  331. F. Higa, P.H. Edelstein, Infect Immun 69, 4782 (2001)

    Article  CAS  Google Scholar 

  332. H.L. Kornberg, C.M. Elvin, J Gen Microbiol 133, 341 (1987)

    CAS  Google Scholar 

  333. Saier MH, Ramseier TM, Reizer J (1996) In: Neidhardt FC et al (ed) Escherichia coli and Salmonella: cellular and molecular biology, 2nd ed. ASM Press, Washington, DC, p 1325

  334. R.M. Gutierrez-Rios, J.A. Freyre-Gonzalez, O. Resendis, J. Collado-Vides, M. Saier, G. Gosset, BMC Microbiol 7, 53 (2007)

    Article  CAS  Google Scholar 

  335. D. Sarkar, K.A. Siddiquee, M.J. Arauzo-Bravo, T. Oba, K. Shimizu, Arch Microbiol 190, 559 (2008)

    Article  CAS  Google Scholar 

  336. T.M. Ramseier, J. Reizer, E. Küster, W. Hillen, M.H. Saier, FEMS Microbiol Lett 129, 207 (1995)

    CAS  Google Scholar 

  337. T.M. Ramseier, D. Negre, J.C. Cortay, M. Scarabel, A.J. Cozzone, M.H. Saier, J Mol Biol 234, 28 (1993)

    Article  CAS  Google Scholar 

  338. S. Ryu, T.M. Ramseier, V. Michotey, M.H. Saier Jr, S. Garges, J Biol Chem 270, 2489 (1995)

    Article  CAS  Google Scholar 

  339. J.S. Parkinson, P. Ames, C.A. Studdert, Curr Opin Microbiol 8, 116 (2005)

    Article  CAS  Google Scholar 

  340. V. Sourjik, N.S. Wingreen, Curr Opin Cell Biol 24, 262 (2012)

    Article  CAS  Google Scholar 

  341. J. Adler, G.L. Hazelbauer, M.M. Dahl, J Bacteriol 115, 824 (1973)

    CAS  Google Scholar 

  342. J. Adler, W. Epstein, Proc Natl Acad Sci USA 71, 2895 (1974)

    Article  CAS  Google Scholar 

  343. M. Niwano, B.L. Taylor, Proc Natl Acad Sci USA 79, 11 (1982)

    Article  CAS  Google Scholar 

  344. R. Lux, K. Jahreis, K. Bettenbrock, J.S. Parkinson, J.W. Lengeler, Proc Natl Acad Sci USA 92, 11583 (1995)

    Article  CAS  Google Scholar 

  345. R. Lux, V.R. Munasinghe, F. Castellano, J.W. Lengeler, J.E. Corrie, S. Khan, Mol Biol Cell 10, 1133 (1999)

    CAS  Google Scholar 

  346. S. Neumann, K. Grosse, V. Sourjik, Proc Natl Acad Sci USA 109, 12159 (2012)

    Article  CAS  Google Scholar 

  347. C. Le Bouguenec, C. Schouler, Int J Med Microbiol 301, 1 (2011)

    Article  CAS  Google Scholar 

  348. M.J. Mahan, D.M. Heithoff, R.L. Sinsheimer, D.A. Low, Annu Rev Genet 34, 139 (2000)

    Article  CAS  Google Scholar 

  349. A. Gotz, W. Goebel, Microbiology 156, 1176 (2010)

    Article  CAS  Google Scholar 

  350. S.D. Bowden, G. Rowley, J.C. Hinton, A. Thompson, Infect Immun 77, 3117 (2009)

    Article  CAS  Google Scholar 

  351. M. Kok, G. Bron, B. Erni, S. Mukhija, Microbiology 149, 2645 (2003)

    Article  CAS  Google Scholar 

  352. C. Chiang, C. Bongiorni, M. Perego, J Bacteriol 193, 52 (2011)

    Article  CAS  Google Scholar 

  353. B. Tsvetanova, A.C. Wilson, C. Bongiorni, C. Chiang, J.A. Hoch, M. Perego, Mol Microbiol 63, 644 (2007)

    Article  CAS  Google Scholar 

  354. T.G. Hammerstrom, J.H. Roh, E.P. Nikonowicz, T.M. Koehler, Mol Microbiol 82, 634 (2011)

    Article  CAS  Google Scholar 

  355. J. Deutscher, R. Herro, A. Bourand, I. Mijakovic, S. Poncet, Biochim Biophys Acta 1754, 118 (2005)

    Article  CAS  Google Scholar 

  356. A.K. Marr, B. Joseph, S. Mertins, R. Ecke, S. Muller-Altrock, W. Goebel, J Bacteriol 188, 3887 (2006)

    Article  CAS  Google Scholar 

  357. R.J. Ellis, Curr Opin Struct Biol 11, 114 (2001)

    Article  CAS  Google Scholar 

  358. Q.K. Beg, A. Vazquez, J. Ernst, M.A. de Menezes, Z. Bar-Joseph, A.L. Barabasi, Z.N. Oltvai, Proc Natl Acad Sci USA 104, 12663 (2007)

    Article  CAS  Google Scholar 

  359. J.M. Rohwer, P.W. Postma, B.N. Kholodenko, H.V. Westerhoff, Proc Natl Acad Sci USA 95, 10547 (1998)

    Article  CAS  Google Scholar 

  360. A. Kremling, K. Jahreis, J.W. Lengeler, E.D. Gilles, Metab Eng 2, 190 (2000)

    Article  CAS  Google Scholar 

  361. A. Kremling, Adv Exp Med Biol 736, 579 (2012)

    Article  Google Scholar 

  362. A. Kremling, D. Flockerzi, J Theor Biol 303, 62 (2012)

    Article  CAS  Google Scholar 

  363. A. Kremling, K. Bettenbrock, B. Laube, K. Jahreis, J.W. Lengeler, E.D. Gilles, Metab Eng 3, 362 (2001)

    Article  CAS  Google Scholar 

  364. T. Sauter, E.D. Gilles, J Biotechnol 110, 181 (2004)

    Article  CAS  Google Scholar 

  365. K. Bettenbrock, S. Fischer, A. Kremling, K. Jahreis, T. Sauter, E.D. Gilles, J Biol Chem 281, 2578 (2006)

    Article  CAS  Google Scholar 

  366. K.C. Kao, L.M. Tran, J.C. Liao, J Biol Chem 280, 36079 (2005)

    Article  CAS  Google Scholar 

  367. J.T. Noel, A. Narang, Bull Math Biol 71, 453 (2009)

    Article  CAS  Google Scholar 

  368. A. Veliz-Cuba, B. Stigler, J Comput Biol 18, 783 (2011)

    Article  CAS  Google Scholar 

  369. H. Ishizuka, A. Hanamura, T. Kunimura, H. Aiba, Mol Microbiol 10, 341 (1993)

    Article  CAS  Google Scholar 

  370. M. Thattai, B.I. Shraiman, Biophys J 85, 744 (2003)

    Article  CAS  Google Scholar 

  371. L. Lopian, Y. Elisha, A. Nussbaum-Shochat, O. Amster-Choder, EMBO J 29, 3630 (2010)

    Article  CAS  Google Scholar 

  372. H.V. Patel, K.A. Vyas, X. Li, R. Savtchenko, S. Roseman, Proc Natl Acad Sci USA 101, 17486 (2004)

    Article  CAS  Google Scholar 

  373. C. Francke, P.W. Postma, H.V. Westerhoff, J.G. Blom, M.A. Peletier, Biophys J 85, 612 (2003)

    Article  CAS  Google Scholar 

  374. A. Kremling, S. Kremling, K. Bettenbrock, FEBS J 276, 594 (2009)

    Article  CAS  Google Scholar 

  375. E.V. Nikolaev, Metab Eng 12, 26 (2010)

    Article  CAS  Google Scholar 

  376. G. Gosset, Microb Cell Fact 4, 14 (2005)

    Article  CAS  Google Scholar 

  377. A. Escalante, C.A. Salinas, G. Gosset, F. Bolivar, Appl Microbiol Biotechnol 94, 1483 (2012)

    Article  CAS  Google Scholar 

  378. A.R. Lara, L. Caspeta, G. Gosset, F. Bolivar, O.T. Ramirez, Biotechnol Bioeng 99, 893 (2008)

    Article  CAS  Google Scholar 

  379. K. Martinez, R. De Anda, G. Hernandez, A. Escalante, G. Gosset, O.T. Ramirez, F.G. Bolivar, Microb Cell Fact 7, 1 (2008)

    Article  CAS  Google Scholar 

  380. A. Escalante, R. Calderon, A. Valdivia, R. De Anda, G. Hernandez, O.T. Ramirez, G. Gosset, F. Bolivar, Microb Cell Fact 9, 21 (2010)

    Article  CAS  Google Scholar 

  381. R. De Anda, A.R. Lara, V. Hernandez, V. Hernandez-Montalvo, G. Gosset, F. Bolivar, O.T. Ramirez, Metab Eng 8, 281 (2006)

    Article  CAS  Google Scholar 

  382. S. Siedler, S. Bringer, L.M. Blank, M. Bott, Appl Microbiol Biotechnol 93, 1459 (2012)

    Article  CAS  Google Scholar 

  383. Y.S. Jung, M. Cai, G.M. Clore, J Biol Chem 287, 23819 (2012)

    Article  CAS  Google Scholar 

  384. P. Csermely, V. Agoston, S. Pongor, Trends Pharmacol Sci 26, 178 (2005)

    Article  CAS  Google Scholar 

  385. B. Erni, J Bacteriol 188, 7036 (2006)

    Article  CAS  Google Scholar 

  386. P. Naves, G. del Prado, L. Huelves, M. Gracia, V. Ruiz, J. Blanco, G. Dahbi, M. Blanco, M.C. Ponte, F. Soriano, Microb Pathog 45, 86 (2008)

    Article  CAS  Google Scholar 

  387. J.R. Johnson, O. Clermont, M. Menard, M.A. Kuskowski, B. Picard, E. Denamur, J Infect Dis 194, 1141 (2006)

    Article  CAS  Google Scholar 

  388. G. Li, C. Laturnus, C. Ewers, L.H. Wieler, Infect Immun 73, 2818 (2005)

    Article  CAS  Google Scholar 

  389. K. Ejrnaes, Dan Med Bull 58, B4187 (2011)

    Google Scholar 

  390. A. Ostblom, I. Adlerberth, A.E. Wold, F.L. Nowrouzian, Appl Environ Microbiol 77, 2303 (2011)

    Article  CAS  Google Scholar 

  391. J.R. Johnson, K. Owens, A. Gajewski, M.A. Kuskowski, J Clin Microbiol 43, 6064 (2005)

    Article  CAS  Google Scholar 

  392. A.L. Lloyd, T.A. Henderson, P.D. Vigil, H.L. Mobley, J Bacteriol 191, 3469 (2009)

    Article  CAS  Google Scholar 

  393. M.A. Khan, R.E. Isaacson, Infect Immun 70, 3404 (2002)

    Article  CAS  Google Scholar 

  394. M.A. Khan, R.E. Isaacson, J Bacteriol 180, 4746 (1998)

    CAS  Google Scholar 

  395. S.L. Chen, C.S. Hung, J. Xu, C.S. Reigstad, V. Magrini, A. Sabo, D. Blasiar, T. Bieri, R.R. Meyer, P. Ozersky, J.R. Armstrong, R.S. Fulton, J.P. Latreille, J. Spieth, T.M. Hooton, E.R. Mardis, S.J. Hultgren, J.I. Gordon, Proc Natl Acad Sci USA 103, 5977 (2006)

    Article  CAS  Google Scholar 

  396. V. Martinez-Jehanne, C. Pichon, L. du Merle, O. Poupel, N. Cayet, C. Bouchier, C. Le Bouguenec, Infect Immun 80, 2655 (2012)

    Google Scholar 

  397. D. Becker, M. Selbach, C. Rollenhagen, M. Ballmaier, T.F. Meyer, M. Mann, D. Bumann, Nature 440, 303 (2006)

    Article  CAS  Google Scholar 

  398. A.K. Turner, M.A. Lovell, S.D. Hulme, L. Zhang-Barber, P.A. Barrow, Infect Immun 66, 2099 (1998)

    CAS  Google Scholar 

  399. A.L. Richard, J.H. Withey, S. Beyhan, F. Yildiz, V.J. DiRita, Mol Microbiol 78, 1171 (2010)

    Article  CAS  Google Scholar 

  400. A. de las Heras, R.J. Cain, M.K. Bielecka, J.A. Vazquez-Boland, Curr Opin Microbiol 14, 118 (2011)

    Article  CAS  Google Scholar 

  401. F.M. Ake, P. Joyet, J. Deutscher, E. Milohanic, Mol Microbiol 81, 274 (2011)

    Article  CAS  Google Scholar 

  402. J.H. Allen, M. Utley, B.H. van Den, P. Nuijten, M. Witvliet, B.A. McCormick, K.A. Krogfelt, T.R. Licht, D. Brown, M. Mauel, M.P. Leatham, D.C. Laux, P.S. Cohen, Infect Immun 68, 3772 (2000)

    Article  CAS  Google Scholar 

  403. A. Antunes, I. Martin-Verstraete, B. Dupuy, Mol Microbiol 79, 882 (2011)

    Article  CAS  Google Scholar 

  404. C.E. Hill, D.S. Metcalf, J.I. MacInnes, Vet Microbiol 96, 189 (2003)

    Article  CAS  Google Scholar 

  405. Y.H. Sun, S. Bakshi, R. Chalmers, C.M. Tang, Nat Med 6, 1269 (2000)

    Article  CAS  Google Scholar 

  406. J. Choi, D. Shin, H. Yoon, J. Kim, C.R. Lee, M. Kim, Y.J. Seok, S. Ryu, Proc Natl Acad Sci USA 107, 20506 (2010)

    Article  CAS  Google Scholar 

  407. L.C. Ma, C.T. Fang, C.Z. Lee, C.T. Shun, J.T. Wang, J Infect Dis 192, 117 (2005)

    Article  CAS  Google Scholar 

  408. T. Barbier, C. Nicolas, J.J. Letesson, FEBS Lett 585, 2929 (2011)

    Article  CAS  Google Scholar 

  409. M. Dozot, S. Poncet, C. Nicolas, R. Copin, H. Bouraoui, A. Maze, J. Deutscher, X. De Bolle, J.J. Letesson, PLoS ONE 5, e12679 (2010)

    Article  CAS  Google Scholar 

  410. L. Houot, S. Chang, B.S. Pickering, C. Absalon, P.I. Watnick, J Bacteriol 192, 3055 (2010)

    Article  CAS  Google Scholar 

  411. L. Houot, S. Chang, C. Absalon, P.I. Watnick, Infect Immun 78, 1482 (2010)

    Article  CAS  Google Scholar 

  412. B.S. Pickering, D.R. Smith, P.I. Watnick, MBio 3, in press (2012)

  413. L. Zhan, Y. Han, L. Yang, J. Geng, Y. Li, H. Gao, Z. Guo, W. Fan, G. Li, L. Zhang, C. Qin, D. Zhou, R. Yang, Infect Immun 76, 5028 (2008)

    Article  CAS  Google Scholar 

  414. M.W. Tan, L.G. Rahme, J.A. Sternberg, R.G. Tompkins, F.M. Ausubel, Proc Natl Acad Sci USA 96, 2408 (1999)

    Article  CAS  Google Scholar 

  415. B.N. Kholodenko, J.M. Rohwer, M. Cascante, H.V. Westerhoff, Mol Cell Biochem 184, 311 (1998)

    Article  CAS  Google Scholar 

  416. K. Van Dam, J. Van der Vlag, B.N. Kholodenko, H.V. Westerhoff, Eur J Biochem 212, 791 (1993)

    Article  Google Scholar 

  417. E.M. Ozbudak, M. Thattai, H.N. Lim, B.I. Shraiman, A. van Oudenaarden, Nature 427, 737 (2004)

    Article  CAS  Google Scholar 

  418. M. Santillan, M.C. Mackey, Biophys J 86, 1282 (2004)

    Article  CAS  Google Scholar 

  419. M. Santillan, M.C. Mackey, E.S. Zeron, Biophys J 92, 3830 (2007)

    Article  CAS  Google Scholar 

  420. J.V. Rodriguez, J.A. Kaandorp, M. Dobrzynski, J.G. Blom, Bioinformatics 22, 1895 (2006)

    Article  CAS  Google Scholar 

  421. H.M. Hardin, A. Zagaris, K. Krab, H.V. Westerhoff, FEBS J 276, 5491 (2009)

    Article  CAS  Google Scholar 

  422. R. Shi, L. McDonald, Q. Cui, A. Matte, M. Cygler, I. Ekiel, Proc Natl Acad Sci USA 108, 1302 (2011)

    Google Scholar 

Download references

Acknowledgments

I would like to thank the late Pieter Postma who introduced me to the PTS in 1981, all the technicians, graduate students, and postdoctoral fellows who substantially contributed to the research progress of my group, and the friends from other groups who helped us with collaborations. I am also grateful to the universities of Basel, Marburg and Bern, and to all the public and private science foundations for their constant and always generous support.

Author information

Authors and Affiliations

  1. Department of Chemistry and Biochemistry, University of Bern, Bern, Switzerland

    Bernhard Erni

Authors
  1. Bernhard Erni
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Bernhard Erni.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Erni, B. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS): an interface between energy and signal transduction. J IRAN CHEM SOC 10, 593–630 (2013). https://doi.org/10.1007/s13738-012-0185-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13738-012-0185-1

Keywords

Search

Navigation