Abstract
Background
Dumping syndrome is one of ten most common complications in morbidly obese patients operated. Recent studies in relation to type 2 diabetes mellitus (DM2) in patients submitted to gastric bypass led us to examine the different outcomes in this group of patients. Our objective was to determine the difference in the prevalence of dumping syndrome in patients with DM2 submitted to gastric bypass.
Methods
In this retrospective study, 49 diabetic and 54 non-diabetic morbidly obese patients were submitted to gastric bypass and followed up at 3, 6, and 12 months after surgery. The occurrence of dumping was determined by the patient’s medical chart, where it was considered positive if recorded in at least one of three evaluations.
Results
The 103 patients evaluated had a mean BMI of 49.5 ± 9.3 kg/m2 and mean age of 38 ± 9.7 years, with 75.7% being women. The prevalence of dumping syndrome in this population was 24.3%. The prevalence of dumping was greater in patients with DM2 (44.9%) when compared to the control group (5.6%; p < 0.001). Multivariate logistic regression analysis indicated the diagnosis of DM2 as the only variable associated with dumping syndrome.
Conclusions
Dumping syndrome is a common postoperative complication in gastric bypass. Patients with DM2 show a greater postoperative prevalence of dumping.
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References
Rubino F, Forgione A, Cummings DE, et al. The mechanism of diabetes control after gastrointestinal bypass surgery reveals a role of the proximal small intestine in the pathophysiology of type 2 diabetes. Ann Surg. 2006;244:741–9.
Ballantyne GH. Peptide YY(1–36) and peptide YY(3–36): part I. Distribution, release and actions. Obes Surg. 2006;16:651–8.
Ballantyne GH. Peptide YY(1–36) and peptide YY(3–36): part II. Changes after gastrointestinal surgery and bariatric surgery. Obes Surg. 2006;16:795–803.
Mason EE. The mechanisms of surgical treatment of type 2 diabetes. Obes Surg. 2005;15:459–61.
Lima J, Helena L, Oliveira S, et al. Rapid resolution of diabetes after gastric bypass. Obes Surg. 2005;15:448–9.
Rubino F, Marescaux J. Effect of duodenal-jejunal exclusion in a non-obese animal model of type 2 diabetes: a new perspective for an old disease. Ann Surg. 2004;239:1–11.
Rubino F, Gagner M, Gentileschi P, et al. The early effect of the Roux-en-Y gastric bypass on hormones involved in body weight regulation and glucose metabolism. Ann Surg. 2004;240:236–42.
Cummings DE, Overduin J, Foster-Schubert KE. Gastric bypass for obesity: mechanisms of weight loss and diabetes resolution. J Clin Endocrinol Metab. 2004;89:2608–15.
Acknowledgments
The authors would like to thank Ceres Oliveira for her assistance in the statistical analysis. We also thank Dr. A. Leyva for his help with translation and English editing of the final draft of the manuscript.
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Padoin, A.V., Neto, M.G., Moretto, M. et al. Obese Patients with Type 2 Diabetes Submitted to Banded Gastric Bypass: Greater Incidence of Dumping Syndrome. OBES SURG 19, 1481–1484 (2009). https://doi.org/10.1007/s11695-009-9943-2
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DOI: https://doi.org/10.1007/s11695-009-9943-2