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The stuff dreams are made of: anatomical substrates of REM sleep

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Exactly how animals switch between different sleep states remains unknown. A new study in Nature provides a glimpse into the mechanisms and anatomy of the brain regions that trigger rapid eye movement sleep.

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Figure 1: Location of the “REM sleep-on” (in red) regions in the rat and cat, and speculation on the likely location of the same region in humans.

References

  1. Lu, J., Sherman, D., Devor, M. & Saper, C.B. Nature (2006) published online 10 May 2006 (doi:10.1038/nature04767).

  2. Siegel, J.M. Nature 437, 1264–1271 (2005).

    Article  CAS  Google Scholar 

  3. Siegel, J.M. in Principles and Practice of Sleep Medicine (eds. Kryger, M.H., Roth, T. & Dement, W.C.) 120–135 (Elsevier Saunders, Philadelphia, 2005).

    Book  Google Scholar 

  4. Sakai, K., Crochet, S. & Onoe, H. Arch. Ital. Biol. 139, 93–107 (2001).

    CAS  Google Scholar 

  5. Boissard, R. et al. Eur. J. Neurosci. 16, 1959–1973 (2002).

    Article  Google Scholar 

  6. Karczmar, A.G., Longo, V.G. & Scotti, D.C. Physiol. Behav. 5, 175–182 (1970).

    Article  CAS  Google Scholar 

  7. Kodama, T., Lai, Y.Y. & Siegel, J.M. Brain Res. 580, 348–350 (1992).

    Article  CAS  PubMed  Google Scholar 

  8. Benington, J.H., Kodali, S.K. & Heller, H.C. Sleep 17, 28–36 (1994).

    Article  CAS  PubMed  Google Scholar 

  9. McGinty, D.J. & Siegel, J.M. Prog. Psychobiol. Physiol. Psychol. 15, 85–140 (1992).

    Google Scholar 

  10. Gvilia, I., Turner, A., McGinty, D. & Szymusiak, R. J. Neurosci. 26, 3037–3044 (2006).

    Article  CAS  PubMed  Google Scholar 

  11. Mileykovskiy, B.Y., Kiyashchenko, L.I. & Siegel, J.M. Neuron 46, 787–798 (2005).

    Article  CAS  Google Scholar 

  12. Thannickal, T.C. et al. Neuron 27, 469–474 (2000).

    Article  CAS  PubMed  Google Scholar 

  13. John, J., Wu, M.-F., Boehmer, L.N. & Siegel, J.M. Neuron 42, 619–634 (2004).

    Article  CAS  PubMed  Google Scholar 

  14. Siegel, J.M. et al. Science 252, 1315–1318 (1991).

    Article  CAS  PubMed  Google Scholar 

  15. Lai, Y.Y. et al. J. Comp. Neurol. 408, 419–436 (1999).

    Article  CAS  PubMed  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Psychiatry and Brain Research Institute, Center for Sleep Research 151A3, Veterans' Affairs Greater Los Angeles Healthcare System (VA GLAHS), UCLA School of Medicine, 16111 Plummer Street, North Hills, 91343, California, USA

    Jerome M Siegel

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  1. Jerome M Siegel
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Siegel, J. The stuff dreams are made of: anatomical substrates of REM sleep. Nat Neurosci 9, 721–722 (2006). https://doi.org/10.1038/nn0606-721

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