Abstract
We report a unique case involving a pure invasive micropapillary carcinoma (IMPC) of the nipple. At the same time, no cancer cells were found in other glands of the breast. There is no documented literature in the world on the micropapillary carcinoma of the nipple. A 43-year-old female detected a lump growing on her nipple since December 2015; however, she did not seek treatment before the lump enlarged. The patient presented at our hospital and underwent resection of the lump on 14 December 2016. Pathologic examination of the surgical specimen revealed IMPC involving the nipple. The patient underwent unilateral radical surgery. The pathologic examination of the specimen revealed normal breast tissue without cancer cells. Herein, we discuss the characteristics, diagnosis, and treatment of IMPC, hoping to provide further insight for clinicians and pathologists.
![](https://cdn.statically.io/img/media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs12262-021-03232-z/MediaObjects/12262_2021_3232_Fig1_HTML.png)
![](https://cdn.statically.io/img/media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs12262-021-03232-z/MediaObjects/12262_2021_3232_Fig2_HTML.png)
![](https://cdn.statically.io/img/media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs12262-021-03232-z/MediaObjects/12262_2021_3232_Fig3_HTML.png)
![](https://cdn.statically.io/img/media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs12262-021-03232-z/MediaObjects/12262_2021_3232_Fig4_HTML.png)
Similar content being viewed by others
References
Tavassoli FA, Devilee P (2003) Pathology and genetics of tumours of the breast and female genital organs. IARC Press, Lyon, pp 35–36
Fisher ER, Palekar AS, Redmond C et al (1980) Pathologic find-ings from the National Surgical Adjuvant Breast Project ( pro-tocol no. 4). VI. Invasive papillary cancer. Am J Clin Pathol 73:313–322
Siriaunkgul S, Tavassoli FA (1993) Invasive micropapillary carcino-ma of the breast. Mod Pathol 6:35–36
Taketani K, Tokunaga E, Yamashita N et al (2014) A case of invasive micropapillary carcinoma of the breast involving extensive lymph node metastasis. World J Surg Oncol 12(1):84–84
Li L, Zhang H, Zhang XB et al (2016) Consensus and conflict in invasive micropapillary carcinoma: a case report and review of the literature. J Gastrointest Oncol 7(Suppl 1):S55–61
Kaygusuzh EI, Cetiner H, Yavuz H (2014) Clinico-pathological significance of extra-nodal spread in special types of breast cancer. Cancer Biol Med 11(2):116–122
Yun SU, Choi BB, Shu KS et al (2012) Imaging findings of invasive micropapillary carcinoma of the breast. J Breast Cancer 15(1):57–64
Hong-Liang C, Ang D (2015) Comparison of invasive micropapillary and triple negative invasive ductal carcinoma of the breast. Breast 24(6):723–731
Li G, Yang S, Jia Y et al (2016) Invasive micropapillary carcinoma of the breast had poor clinical characteristics but showed no difference in prognosis compared with invasive ductal carcinoma. World J Surg Oncol 14(1):207
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of Interest
The authors declare no competing interests.
Additional information
Publisher’s Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Liu, J., Yu, H. & He, G. Pure Invasive Micropapillary Carcinoma of the Nipple: a Case Report. Indian J Surg 84 (Suppl 3), 825–828 (2022). https://doi.org/10.1007/s12262-021-03232-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12262-021-03232-z