Abstract
Purpose
Access to intervention is a barrier for children with autism. As parent-mediated interventions have emerged to address this need, understanding implementation components contributing to child gains is critically important. Existing literature documents relationships between parent treatment adherence and child progress; however, less is understood about components, such as frequency of learning opportunities, which could also affect child outcomes.
Methods
This study is a secondary analysis of data from a randomized controlled trial evaluating Pivotal Response Treatment group parent training (PRTG) compared to psychoeducation. Linear regression and mediational models were employed to identify potential predictors and mediators of outcome.
Results
PRTG produced large increases in adherence and learning opportunities. In general, greater frequency of learning opportunities and adherence predicted better child outcomes. The best-fitting cross-sectional mediational models indicated at least partial mediational effects, whereby increased learning opportunities mediated the relationship between greater adherence and improved child outcomes.
Conclusions
This study provides preliminary evidence of how early gains in adherence may support parents to provide more frequent learning opportunities, which, in turn, yield positive effects on child social communication. Future large-scale research, with greater granularity of measurement, is needed to further understand the temporal relationships between these variables.
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References
Bentler, P. M. (1990). Comparative fit indexes in structural models. Psychological Bulletin, 107, 238–246. https://doi.org/10.1037/0033-2909.107.2.238.
Bryk, A. S., & Raudenbush, S. W. (1992). Hierarchical linear models: Applications and data analysis methods (pp. xvi, 265). Sage Publications, Inc.
Burrell, T. L., & Borrego, J. (2012). Parents’ involvement in ASD Treatment: What is their role? Cognitive and Behavioral Practice, 19(3), 423–432. https://doi.org/10.1016/j.cbpra.2011.04.003.
Carroll, C., Patterson, M., Wood, S., Booth, A., Rick, J., & Balain, S. (2007). A conceptual framework for implementation fidelity. Implementation Science, 2(1), 40. https://doi.org/10.1186/1748-5908-2-40.
Centers for Disease Control (2023, January 11). Data and Statistics on Autism Spectrum Disorder | CDC. Centers for Disease Control and Prevention. https://www.cdc.gov/ncbddd/autism/data.html.
Cheng, W. M., Smith, T. B., Butler, M., Taylor, T. M., & Clayton, D. (2022). Effects of parent-implemented interventions on outcomes of children with autism: A Meta-analysis. Journal of Autism and Developmental Disorders. https://doi.org/10.1007/s10803-022-05688-8.
Cohen, J. (1960). A Coefficient of Agreement for Nominal Scales—Jacob Cohen, 1960. https://journals.sagepub.com/doi/10.1177/001316446002000104.
Feldman, M. A., & Werner, S. E. (2002). Collateral effects of behavioral parent training on families of children with developmental disabilities and behavior disorders. Behavioral Interventions, 17(2), 75–83. https://doi.org/10.1002/bin.111.
Frost, K. M., Brian, J., Gengoux, G. W., Hardan, A., Rieth, S. R., Stahmer, A., & Ingersoll, B. (2020). Identifying and measuring the common elements of naturalistic developmental behavioral interventions for autism spectrum disorder: Development of the NDBI-Fi. Autism: The International Journal of Research and Practice, 24(8), 2285–2297. https://doi.org/10.1177/1362361320944011.
Fuller, E. A., & Kaiser, A. P. (2020). The effects of Early Intervention on Social Communication Outcomes for Children with Autism Spectrum disorder: A Meta-analysis. Journal of Autism and Developmental Disorders, 50(5), 1683–1700. https://doi.org/10.1007/s10803-019-03927-z.
Gengoux, G. W., Berquist, K. L., Salzman, E., Schapp, S., Phillips, J. M., Frazier, T. W., Minjarez, M. B., & Hardan, A. Y. (2015). Pivotal response treatment parent training for Autism: Findings from a 3-Month Follow-Up evaluation. Journal of Autism and Developmental Disorders, 45(9), 2889–2898. https://doi.org/10.1007/s10803-015-2452-3.
Gengoux, G. W., Abrams, D. A., Schuck, R., Millan, M. E., Libove, R., Ardel, C. M., Phillips, J. M., Fox, M., Frazier, T. W., & Hardan, A. Y. (2019). A Pivotal Response Treatment Package for Children with Autism Spectrum Disorder: An RCT. Pediatrics, 144(3), e20190178. https://doi.org/10.1542/peds.2019-0178.
Guy, W. (1976). ECDEU assessment manual for psychopharmacology. U.S. Department of Health, Education, and Welfare.
Hampton, L. H., & Kaiser, A. P. (2016). Intervention effects on spoken-language outcomes for children with autism: A systematic review and meta-analysis. Journal of Intellectual Disability Research, 60(5), 444–463. https://doi.org/10.1111/jir.12283.
Hardan, A. Y., Gengoux, G. W., Berquist, K. L., Libove, R. A., Ardel, C. M., Phillips, J., Frazier, T. W., & Minjarez, M. B. (2015). A randomized controlled trial of Pivotal Response Treatment Group for parents of children with autism. Journal of Child Psychology and Psychiatry, 56(8), 884–892. https://doi.org/10.1111/jcpp.12354.
IBM, C. (2019). IBM SPSS statistics for Windows, Version 26.0. IBM Corp.
Ingersoll, B., Wainer, A. L., Berger, N. I., Pickard, K. E., & Bonter, N. (2016). Comparison of a Self-Directed and Therapist-assisted Telehealth parent-mediated intervention for children with ASD: A pilot RCT. Journal of Autism and Developmental Disorders, 46(7), 2275–2284. https://doi.org/10.1007/s10803-016-2755-z.
Jones, T. L., & Prinz, R. J. (2005). Potential roles of parental self-efficacy in parent and child adjustment: A review. Clinical Psychology Review, 25(3), 341–363. https://doi.org/10.1016/j.cpr.2004.12.004.
Kasari, C., Lawton, K., Shih, W., Barker, T. V., Landa, R., Lord, C., Orlich, F., King, B., Wetherby, A., & Senturk, D. (2014). Caregiver-mediated intervention for low-resourced preschoolers with autism: An RCT. Pediatrics, 134(1), e72–e79. https://doi.org/10.1542/peds.2013-3229.
Koegel, R. L., Camarata, S., Koegel, L. K., Ben-Tall, A., & Smith, A. E. (1998). Increasing Speech Intelligibility in Children with Autism. Journal of Autism and Developmental Disorders, 28(3), 241–251. https://doi.org/10.1023/A:1026073522897.
Koegel, L. K., Carter, C. M., & Koegel, R. L. (2003). Teaching children with autism self-initiations as a pivotal response. Topics in Language Disorders, 23, 134–145. https://doi.org/10.1097/00011363-200304000-00006.
Lang, R., Hancock, T. B., & Singh, N. N. (2016). Overview of Early Intensive Behavioral Intervention for Children with Autism. In R. Lang, T. B. Hancock, & N. N. Singh (Eds.), Early Intervention for Young Children with Autism Spectrum Disorder (pp. 1–14). Springer International Publishing. https://doi.org/10.1007/978-3-319-30925-5_1.
Maenner, M. J. (2023). Prevalence and Characteristics of Autism Spectrum Disorder Among Children Aged 8 Years—Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2020. MMWR. Surveillance Summaries, 72. https://doi.org/10.15585/mmwr.ss7202a1.
Magiati, I., Tay, X. W., & Howlin, P. (2014). Cognitive, language, social and behavioural outcomes in adults with autism spectrum disorders: A systematic review of longitudinal follow-up studies in adulthood. Clinical Psychology Review, 34(1), 73–86. https://doi.org/10.1016/j.cpr.2013.11.002.
Marsh, H. W., Hau, K. T., & Wen, Z. (2004). In search of Golden rules: Comment on hypothesis-testing approaches to setting cutoff values for fit indexes and dangers in overgeneralizing Hu and Bentler’s (1999) findings. Structural Equation Modeling: A Multidisciplinary Journal, 11(3), 320–341. https://doi.org/10.1207/s15328007sem1103_2.
McConachie, H., & Fletcher-Watson, S. & Working Group 4, C. A. ‘Enhancing the S. S. of E. A. (2015). Building capacity for rigorous controlled trials in autism: The importance of measuring treatment adherence. Child: Care Health and Development, 41(2), 169–177. https://doi.org/10.1111/cch.12185.
Minjarez, M. B., Williams, S. E., Mercier, E. M., & Hardan, A. Y. (2011). Pivotal Response Group Treatment Program for Parents of Children with autism. Journal of Autism and Developmental Disorders, 41(1), 92–101. https://doi.org/10.1007/s10803-010-1027-6.
Minjarez, M. B., Mercier, E. M., Williams, S. E., & Hardan, A. Y. (2013). Impact of Pivotal Response Training Group Therapy on Stress and Empowerment in parents of children with autism. Journal of Positive Behavior Interventions, 15(2), 71–78. https://doi.org/10.1177/1098300712449055.
Mouton, B., Loop, L., Stiévenart, M., & Roskam, I. (2018). Confident parents for easier children: A parental self-efficacy program to improve Young Children’s behavior. Education Sciences, 8(3). https://doi.org/10.3390/educsci8030134.
Mullen, E. (1995). Mullen scales of early learning: AGS Edition. Circle Pines, MN: American Guidance Service Inc
Muthén, L. K., & Muthén, B. O. (1998). Mplus user’s guide (7th ed.).). Muthén & Muthén.
National Autism Center (2015). Findings and conclusions: National standards project, phase 2
National Research Council. (2001). Educating children with autism. National Academies. https://doi.org/10.17226/10017.
Nevill, R. E., Lecavalier, L., & Stratis, E. A. (2018). Meta-analysis of parent-mediated interventions for young children with autism spectrum disorder. Autism: The International Journal of Research and Practice, 22(2), 84–98. https://doi.org/10.1177/1362361316677838.
Penney, A., & Schwartz, I. (2019). Effects of coaching on the fidelity of parent implementation of reciprocal imitation training. Autism, 23(6), 1497–1507. https://doi.org/10.1177/1362361318816688.
Peugh, J. L., & Enders, C. K. (2005). Using the SPSS mixed Procedure to Fit cross-sectional and longitudinal Multilevel models. Educational and Psychological Measurement, 65, 717–741. https://doi.org/10.1177/0013164405278558.
Pickard, K., Mellman, H., Frost, K., Reaven, J., & Ingersoll, B. (2023). Balancing Fidelity and Flexibility: Usual Care for Young Children with an increased likelihood of having Autism Spectrum Disorder within an early intervention system. Journal of Autism and Developmental Disorders, 53(2), 656–668. https://doi.org/10.1007/s10803-021-04882-4.
Pierce, K., & Schreibman, L. (1997). Multiple peer use of pivotal response training to increase social behaviors of classmates with autism: Results from trained and untrained peers. Journal of Applied Behavior Analysis, 30(1), 157–160. https://doi.org/10.1901/jaba.1997.30-157.
Reichow, B., & Wolery, M. (2009). Comprehensive synthesis of early intensive behavioral interventions for Young Children with Autism based on the UCLA Young Autism Project Model. Journal of Autism and Developmental Disorders, 39(1), 23–41. https://doi.org/10.1007/s10803-008-0596-0.
Roberts, M. Y., Curtis, P. R., Sone, B. J., & Hampton, L. H. (2019). Association of Parent Training with Child Language Development: A systematic review and Meta-analysis. JAMA Pediatrics, 173(7), 671–680. https://doi.org/10.1001/jamapediatrics.2019.1197.
Russell, K. M., & Ingersoll, B. (2021). Factors related to parental therapeutic self-efficacy in a parent-mediated intervention for children with autism spectrum disorder: A mixed methods study. Autism, 25(4), 971–981. https://doi.org/10.1177/1362361320974233.
Schreibman, L., Dawson, G., Stahmer, A. C., Landa, R., Rogers, S. J., McGee, G. G., Kasari, C., Ingersoll, B., Kaiser, A. P., Bruinsma, Y., McNerney, E., Wetherby, A., & Halladay, A. (2015). Naturalistic developmental behavioral interventions: Empirically validated treatments for Autism Spectrum Disorder. Journal of Autism and Developmental Disorders, 45(8), 2411–2428. https://doi.org/10.1007/s10803-015-2407-8.
Shire, S. Y., Shih, W., Barriault, T., & Kasari, C. (2022). Exploring coaching and follow-up supports in community-implemented caregiver-mediated JASPER intervention. Autism, 26(3), 654–665. https://doi.org/10.1177/13623613211066132.
Sone, B. J., Kaat, A. J., & Roberts, M. Y. (2021). Measuring parent strategy use in early intervention: Reliability and validity of the naturalistic developmental behavioral intervention Fidelity Rating Scale across strategy types. Autism, 25(7), 2101–2111. https://doi.org/10.1177/13623613211015003.
Steinbrenner, J. R., Hume, K., Odom, S. L., Morin, K. L., Nowell, S. W., Tomaszewski, B., Szendrey, S., McIntyre, N. S., Yücesoy-Özkan, Ş., & Savage, M. N. (2020). Evidence-based practices for children, youth, and young adults with autism. The University of North Carolina at Chapel Hill, Frank Porter Graham Child Development Institute, National Clearinghouse on Autism Evidence and Practice Review Team.
Stiévenart, M., & Martinez Perez, T. (2021). How can parental self-efficacy support children’s early language development? Review of preliminary research and future perspectives. European Journal of Developmental Psychology, 18(2), 199–213. https://doi.org/10.1080/17405629.2020.1776102.
Strain, P. S., & Hoyson, M. (2000). The Need for Longitudinal, Intensive Social Skill Intervention: LEAP Follow-Up Outcomes for Children with Autism—Phillip S. Strain, Marilyn Hoyson, 2000. https://journals.sagepub.com/doi/10.1177/027112140002000207.
Symon, J. B. (2005). Expanding interventions for children with autism: Parents as trainers. Journal of Positive Behavior Interventions, 7(3), 159–173. https://doi.org/10.1177/10983007050070030501.
Tiede, G., & Walton, K. M. (2019). Meta-analysis of naturalistic developmental behavioral interventions for young children with autism spectrum disorder—Gabrielle Tiede, Katherine M. Walton, 2019. https://journals.sagepub.com/doi/10.1177/1362361319836371?url_ver=Z39.88-2003&_id=ori:rid:crossref.org&_dat=cr_pub%20%200pubmed.
Vibert, B. A., Dufek, S., Klein, C., Choi, Y. B., Winter, J., Lord, C., & Kim, S. H. (2020). Quantifying caregiver change across early autism interventions using the measure of NDBI Strategy implementation – caregiver change (MONSI-CC). Journal of Autism and Developmental Disorders, 50(4), 1364–1379. https://doi.org/10.1007/s10803-019-04342-0.
Virués-Ortega, J. (2010). Applied behavior analytic intervention for autism in early childhood: Meta-analysis, meta-regression and dose–response meta-analysis of multiple outcomes. Clinical Psychology Review, 30(4), 387–399. https://doi.org/10.1016/j.cpr.2010.01.008.
Waddington, H., van der Meer, L., Sigafoos, J., & Whitehouse, A. (2020). Examining parent use of specific intervention techniques during a 12-week training program based on the early start Denver Model. Autism, 24(2), 484–498. https://doi.org/10.1177/1362361319876495.
Weber, L., Kamp-Becker, I., Christiansen, H., & Mingebach, T. (2019). Treatment of child externalizing behavior problems: A comprehensive review and meta-meta-analysis on effects of parent-based interventions on parental characteristics. European Child & Adolescent Psychiatry, 28(8), 1025–1036. https://doi.org/10.1007/s00787-018-1175-3.
Wetherby, A. M., Guthrie, W., Woods, J., Schatschneider, C., Holland, R. D., Morgan, L., & Lord, C. (2014). Parent-implemented social intervention for toddlers with autism: An RCT. Pediatrics, 134(6), 1084–1093. https://doi.org/10.1542/peds.2014-0757.
Zeidan, J., Fombonne, E., Scorah, J., Ibrahim, A., Durkin, M. S., Saxena, S., Yusuf, A., Shih, A., & Elsabbagh, M. (2022). Global prevalence of autism: A systematic review update. Autism Research, 15(5), 778–790. https://doi.org/10.1002/aur.2696.
Zitter, A., Rinn, H., Szapuova, Z., Avila-Pons, V. M., Coulter, K. L., Stahmer, A. C., Robins, D. L., & Vivanti, G. (2021). Does Treatment Fidelity of the Early Start Denver Model Impact Skill Acquisition in Young Children with Autism? Journal of Autism & Developmental Disorders, 1–11. https://doi.org/10.1007/s10803-021-05371-4.
Funding
Dr. Frazier has received funding or research support from, acted as a consultant to, received travel support from, and/or received a speaker’s honorarium from the PTEN Research Foundation, SYNGAP Research Fund, Malan Syndrome Foundation, ADNP Kids Research Foundation, Quadrant Biosciences, Autism Speaks, Impel NeuroPharma, F. Hoffmann-La Roche AG Pharmaceuticals, the Cole Family Research Fund, Simons Foundation, Ingalls Foundation, Forest Laboratories, Ecoeos, IntegraGen, Kugona LLC, Shire Development, Bristol-Myers Squibb, Roche Pharma, MaraBio, Scioto Biosciences, National Institutes of Health, and the Brain and Behavior Research Foundation, has equity options in Quadrant Biosciences/Autism Analytica, MaraBio, and Springtide, and has an investor stake in Autism EYES LLC and iSCAN-R. Dr. Minjarez has received funding or research support from, acted as a consultant to, received travel support from, received royalties from, and/or received a speaker’s honorarium from EarliTec Diagnostics Inc., Marcus Autism Center, Thompson Autism and Neurodevelopmental Center, Actualmente Autism Argentina, Brookes Publishing, Washington State University, National Institutes of Health, Hoffman-LaRoche AG Pharmaceuticals, and Seoul National University. The remaining authors have declared that they have no competing or potential conflicts of interest.
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Minjarez, M.B., Gengoux, G.W., Paszek, K. et al. Adherence and Opportunity Frequency as Predictors of Communication Outcomes from Pivotal Response Parent Training. J Autism Dev Disord (2024). https://doi.org/10.1007/s10803-024-06447-7
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DOI: https://doi.org/10.1007/s10803-024-06447-7