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The diagnostic assessment of fibromyalgia and the role of small fiber pathology

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References

  1. Wolfe F, Clauw DJ, Fitzcharles MA, Goldenberg DL, Häuser W, Katz RL, Mease PJ, Russell AS, Russell IJ, Walitt B (2016) 2016 Revisions to the 2010/2011 fibromyalgia diagnostic criteria. Semin Arthritis Rheum 46(3):319–329

    Article  PubMed  Google Scholar 

  2. de Tommaso M, Vecchio E, Nolano M (2022) The puzzle of fibromyalgia between central sensitization syndrome and small fiber neuropathy: a narrative review on neurophysiological and morphological evidence. Neurol Sci 43:1667–1684

    Article  PubMed  Google Scholar 

  3. Devigili G, Di Stefano G, Donadio V, Frattale I, Mantovani E, Nolano M, Occhipinti G, Provitera V, Quitadamo S, Tamburin S, Toscano A, Tozza S, Truini A, Valeriani M, de Tommaso M (2023) Clinical criteria and diagnostic assessment of fibromyalgia: position statement of the Italian Society of Neurology-Neuropathic Pain Study Group. Neurol Sci 44:2561–2574

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Üçeyler N (2016) Small fiber pathology—a culprit for many painful disorders? Pain 157:S60–S66

    Article  PubMed  Google Scholar 

  5. Kosek E, Clauw D, Nijs J, Baron R, Gilron I, Harris RE, Mico JA, Rice ASC, Sterling M (2021) Chronic nociplastic pain affecting the musculoskeletal system: clinical criteria and grading system. Pain 162:2629–2634

    Article  PubMed  Google Scholar 

  6. Oaklander AL, Herzog ZD, Downs HM, Klein MM (2013) Objective evidence that small-fiber polyneuropathy underlies some illnesses currently labeled as fibromyalgia. Pain 154(11):2310–2316

    Article  PubMed  Google Scholar 

  7. Lodahl M, Treister R, Oaklander AL (2017) Specific symptoms may discriminate between fibromyalgia patients with vs without objective test evidence of small- fiber polyneuropathy. Pain Rep 3(1):e633

    Article  PubMed  PubMed Central  Google Scholar 

  8. Evdokimov D, Frank J, Klitsch A, Unterecker S, Warrings B, Serra J, Papagianni A, Saffer N, Altenschildesche MZ, Kampik CD, Malik RA, Sommer C, Üçeyler N (2019) Reduction of skin innervation is associated with a severe fibromyalgia phenotype. Ann Neurol 86(4):504–516

    Article  CAS  PubMed  Google Scholar 

  9. Truini A, Aleksovska K, Anderson CC et al (2023) Joint European Academy of Neurology–European Pain Federation–Neuropathic Pain Special Interest Group of the International Association for the Study of Pain guidelines on neuropathic pain assessment. Eur J Neurol 30:2177–2196

    Article  PubMed  Google Scholar 

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Correspondence to Franco Gemignani.

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Gemignani, F. The diagnostic assessment of fibromyalgia and the role of small fiber pathology. Neurol Sci 45, 1789–1790 (2024). https://doi.org/10.1007/s10072-023-07207-8

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