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Drying of pendant drops of blood

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Abstract

The analysis of patterns in dried blood droplets has made it possible to generate strategies to detect health problems in patients and to address problems in forensic sciences. Therefore, studying various forms of droplet drying could enhance the efficiency of pathology diagnosis and the comprehension of crime scenes. In this paper, we report the study of the pattern formation generated by drying pendant blood droplets with different initial volumes (V = 3–24 \({\mu L}\)). We find two distinct groups of deposits: dried drops with radial symmetry (Group I) and dried drops with lateral deposition of blood serum (Group II). Lateral deposition arises from drop collapse induced by hematocrit agglomeration at the drop apex. Our findings reveal that the collapse process consistently takes place at an angle 11 degrees below the initial contact angle, irrespective of the initial droplet volume. Finally, we provide evidence that the mass contained in a droplet promotes the occurrence of the unstable drying mode.

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Acknowledgements

R.H.S. and Y.J.P.C. wish to acknowledge financial support by the CONACyT fellowship. R.H.S. wishes to acknowledge technical support by ECOn BG. We are sincerely grateful to CONACyT for their generous support under grant CF-2023-G-454.

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Authors and Affiliations

  1. Facultad de Ciencias en Física y Matemáticas, Universidad Autónoma de Chiapas, Calz. Emiliano Zapata Km. 8, Tuxtla Gutieérrez, Chiapas, 29050, México

    Ricardo Herrera-Sandoval, Yojana J. P. Carreón, Orlando Díaz-Hernández & Jorge González-Gutiérrez

  2. CONACyT, 03940, México City, México

    Yojana J. P. Carreón

Authors
  1. Ricardo Herrera-Sandoval
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  2. Yojana J. P. Carreón
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  3. Orlando Díaz-Hernández
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  4. Jorge González-Gutiérrez
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Contributions

Investigation: Y.J.P.C., methodology: R.H.S. and Y.J.P.C., formal analysis: R.H.S. and O.D.H., conceptualization, supervision, writing original draft: J.G.G. Review and editing, R.H.S., Y.J.P.C., and O.D.H. All authors approved the manuscript.

Corresponding author

Correspondence to Jorge González-Gutiérrez.

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Ethical approval

All subjects gave their informed consent for inclusion before they participated in the study. The study was conducted in accordance with the Declaration of Helsinki, and the protocol was approved by the Internal Ethics Committee of Collegiate Research Group Dynamical Systems and Complexity and the Autonomous University of Chiapas (01/FYM/RPR/016/23).

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The authors declare no competing interests.

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Herrera-Sandoval, R., Carreón, Y.J.P., Díaz-Hernández, O. et al. Drying of pendant drops of blood. Colloid Polym Sci 301, 1325–1336 (2023). https://doi.org/10.1007/s00396-023-05155-5

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  • DOI: https://doi.org/10.1007/s00396-023-05155-5

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